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Mantle cell lymphoma
3 associated genes
139 connected diseases
7 signs/symptoms
Disease Type of connection
B-cell chronic lymphocytic leukemia
Precursor B-cell acute lymphoblastic leukemia
Ataxia-telangiectasia
Ataxia-telangiectasia variant
Combined cervical dystonia
Follicular lymphoma
MALT lymphoma
Multiple myeloma
Hereditary breast and ovarian cancer syndrome
Familial pancreatic carcinoma
Familial prostate cancer
Precursor T-cell acute lymphoblastic leukemia
Multiple endocrine neoplasia type 1
Hereditary breast cancer
Hereditary site-specific ovarian cancer syndrome
Fanconi anemia
Seckel syndrome
Familial melanoma
Primary peritoneal carcinoma
Dedifferentiated liposarcoma
Well-differentiated liposarcoma
Constitutional mismatch repair deficiency syndrome
Hereditary nonpolyposis colon cancer
Li-Fraumeni syndrome
Muir-Torre syndrome
Non-polyposis Turcot syndrome
Cornelia de Lange syndrome
Peripheral resistance to thyroid hormones
Autosomal recessive primary microcephaly
Chronic myeloid leukemia
Omenn syndrome
Ear-patella-short stature syndrome
Multiple endocrine neoplasia type 4
Adrenocortical carcinoma
Complete androgen insensitivity syndrome
Essential thrombocythemia
Estrogen resistance syndrome
Familial hypospadias
Familial retinoblastoma
Giant cell glioblastoma
Gliosarcoma
Kennedy disease
Monosomy 13q14
Papilloma of choroid plexus
Partial androgen insensitivity syndrome
Unilateral retinoblastoma
X-linked dystonia-parkinsonism
Bloom syndrome
Nijmegen breakage syndrome
Ataxia-telangiectasia-like disorder
Severe combined immunodeficiency due to DNA-PKcs deficiency
Anhidrotic ectodermal dysplasia - immunodeficiency - osteopetrosis - lymphedema
Autosomal dominant hyper-IgE syndrome
Hypohidrotic ectodermal dysplasia with immunodeficiency
Incontinentia pigmenti
X-linked mendelian susceptibility to mycobacterial diseases due to IKBKG deficiency
Melanoma and neural system tumor syndrome
Melanoma-pancreatic cancer syndrome
Melanoma of soft part
Spinocerebellar ataxia type 1 with axonal neuropathy
Chuvash erythrocytosis
Intellectual deficit, X-linked, Turner type
Von Hippel-Lindau disease
Generalized resistance to thyroid hormone
Selective pituitary resistance to thyroid hormone
Jawad syndrome
Xeroderma pigmentosum complementation group C
Werner syndrome
Beckwith-Wiedemann syndrome due to CDKN1C mutation
Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome
IMAGe syndrome
Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations
Osteosarcoma
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency
Familial congenital mirror movements
Autosomal dominant polycystic kidney disease type 1 with tuberous sclerosis
Lymphangioleiomyomatosis
Tuberous sclerosis
Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy
Atypical teratoid tumor
Autosomal dominant progressive external ophthalmoplegia
Chorioretinopathy, Birdshot type
Coffin-Siris syndrome
Congenital analbuminemia
Familial multiple meningioma
Familial rhabdoid tumor
Kearns-Sayre syndrome
MODY syndrome
Mitochondrial DNA depletion syndrome, encephalomyopathic form with renal tubulopathy
Mitochondrial neurogastrointestinal encephalomyopathy
Neurofibromatosis type 3
Alpha-crystallinopathy
Familial isolated dilated cardiomyopathy
Fatal infantile hypertonic myofibrillar myopathy
Posterior polar cataract
Zonular cataract
Severe combined immunodeficiency due to DCLRE1C deficiency
Split hand-split foot malformation
Infantile Refsum disease
Neonatal adrenoleukodystrophy
Peutz-Jeghers syndrome
Zellweger syndrome
3M syndrome
6-pyruvoyl-tetrahydropterin synthase deficiency
Atelosteogenesis type I
Atelosteogenesis type III
Autosomal dominant Larsen syndrome
Boomerang dysplasia
Burkitt lymphoma
Distal 22q11.2 microdeletion syndrome
Familial lipoprotein lipase deficiency
Hyperlipoproteinemia type 5
LIG4 syndrome
Persistent polyclonal B-cell lymphocytosis
Severe combined immunodeficiency due to CARD11 deficiency
Severe intellectual disability-short stature-behavioral troubles-facial dysmorphism syndrome
Spondylocarpotarsal synostosis
X-linked dominant chondrodysplasia, Chassaing-Lacombe type
Autosomal dominant nonsyndromic intellectual deficit
Craniopharyngioma
Desmoid tumor
Hepatocellular carcinoma, childhood-onset
Pilomatrixoma
Autosomal dominant hypohidrotic ectodermal dysplasia
Nijmegen breakage syndrome-like disorder
Xeroderma pigmentosum complementation group A
Acute myeloid leukemia with t(8;21)(q22;q22) translocation
Aicardi-Goutières syndrome
Anaplastic ependymoma
Catecholaminergic polymorphic ventricular tachycardia
Cerebroretinal vasculopathy
Chilblain lupus
Familial advanced sleep-phase syndrome
Familial platelet syndrome with predisposition to acute myelogenous leukemia
HERNS syndrome
Hereditary vascular retinopathy
Isolated delta-storage pool disease
Premature chromosome condensation with microcephaly and intellectual deficit
Pseudohypoaldosteronism type 2E
Synonym(s):
- LCM
- MCL
- Mantle zone lymphoma
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease
Classification (ICD10):
- Neoplasms -
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: adult
Type of inheritance: multigenic/multifactorial
External references:
No OMIM references
1 MeSH reference: D020522
Gene symbol UniProt reference OMIM reference
ATM Q13315607585
CCND1 P24385168461
IGH Q6P089
Very frequent
- Hematologic / blood / lymphatic cancer
- Lymphadenopathy / polyadenopathies

Frequent
- Anorexia
- Asthenia / fatigue / weakness
- Bone marrow / medullar infiltration
- Splenomegaly
- Weight loss / loss of appetite / break in weight curve / general health alteration