Cytoscape Web
Click node...

Familial platelet syndrome with predisposition to acute myelogenous leukemia
1 OMIM reference -
1 associated gene
54 connected diseases
No signs/symptoms info
Disease Type of connection
Acute myeloid leukemia with t(8;21)(q22;q22) translocation
Precursor B-cell acute lymphoblastic leukemia
Chronic myeloid leukemia
Isolated delta-storage pool disease
Acute myeloid leukemia with t(8;16)(p11;p13) translocation
Precursor T-cell acute lymphoblastic leukemia
Acute promyelocytic leukemia
Familial isolated dilated cardiomyopathy
Autosomal agammaglobulinemia
Coffin-Siris syndrome
Familial rhabdoid tumor
Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)
Short stature due to isolated growth hormone deficiency with X-linked hypogammaglobulinemia
Berardinelli-Seip congenital lipodystrophy
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency
Uveal coloboma - cleft lip and palate - intellectual deficit
Aneurysm - osteoarthritis syndrome
Familial thoracic aortic aneurysm and aortic dissection
Rubinstein-Taybi syndrome due to 16p13.3 microdeletion
Rubinstein-Taybi syndrome due to CREBBP mutations
Hypocalcemic vitamin D-resistant rickets
Acute megakaryoblastic leukemia without Down syndrome
Autosomal recessive primary microcephaly
Cerebellar ataxia-deafness-narcolepsy syndrome
Autosomal dominant hypohidrotic ectodermal dysplasia
Burkitt lymphoma
Papillary or follicular thyroid carcinoma
Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome
Cerebellar ataxia - hypogonadism
Acute myeloid leukemia with CEBPA somatic mutations
Inherited acute myeloid leukemia
Anophthalmia / microphthalmia - esophageal atresia
Atypical teratoid tumor
Blepharophimosis-intellectual deficit syndrome, SBBYS type
Colobomatous microphthalmia
Extraskeletal myxoid chondrosarcoma
Familial multiple meningioma
Genitopatellar syndrome
Isolated anophthalmia - microphthalmia
Isolated brachycephaly
Isolated plagiocephaly
Neurofibromatosis type 3
Noonan syndrome
Septo-optic dysplasia
Young adult-onset Parkinsonism
Barth syndrome
Left ventricular noncompaction
B-cell chronic lymphocytic leukemia
Complete androgen insensitivity syndrome
Familial hypospadias
Kennedy disease
Mantle cell lymphoma
Multiple myeloma
Partial androgen insensitivity syndrome
Synonym(s):
- FPD/AML syndrome
- FPS/AML syndrome
- Familial platelet disorder with associated myeloid malignancy
- Familial platelet syndrome
Classification (Orphanet):
- Rare genetic disease
- Rare hematologic disease
- Rare oncologic disease
Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: no data available
Average age of death: no data available
Type of inheritance: autosomal dominant
External references:
1 OMIM reference -
No MeSH references
Gene symbol UniProt reference OMIM reference
RUNX1 Q01196151385
No signs/symptoms info available.