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Semantic dementia

6 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
14 signs/symptoms

Semantic dementia

Perry syndrome

C9ORF72	(UniProt - OMIM)		DCTN1	(UniProt - OMIM)
CHMP2B	(UniProt - OMIM)
GRN	(UniProt - OMIM)
MAPT	(UniProt - OMIM)
PSEN1	(UniProt - OMIM)
VCP	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MAPT	(0.75)	DCTN1

Citations in the biomedical literature:

Semantic dementia		Perry syndrome
	Synonym(s): - Semantic primary progressive aphasia - Semantic variant PPA		Synonym(s): - Parkinsonism with alveolar hypoventilation and mental depression

	Classification (Orphanet): - Rare genetic disease - Rare neurologic disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Diseases of the nervous system -		Classification (ICD10): (no data available)

	Epidemiological data: Class of prevalence: - Average age onset: adulthood Average age of death: - Type of inheritance: multigenic/multifactorial		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adulthood Average age of death: - Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - No MeSH references

Perry syndrome
	Very frequent - Autosomal dominant inheritance - Execution movement disorder / dysmetria / bradykinesia / akinesia / apraxia - Extrapyramidal syndrome - Humour troubles / anxiety / depression / apathy / euphoria / irritability - Respiratory distress / dyspnea / respiratory failure / lung volume reduction - Sleep and vigilance disorders - Tremor - Weight loss / loss of appetite / break in weight curve / general health alteration Occasional - Delirium / hallucination - Early death / lethality - Hypotension - Psychic / behavioural troubles - Psychic / psychomotor regression / dementia / intellectual decline - Psychosis / schizophrenia / maniac disorder
Semantic dementia
(no data available)