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1 OMIM reference -
6 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
1 associated gene
No signs/symptoms info
Progressive non-fluent aphasia
Limited systemic sclerosis

C9ORF72 HLA-DRB1
CHMP2B
GRN
MAPT
PSEN1
VCP


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
VCP
(0.63)
HLA-DRB1



Citations in the biomedical literature:


Progressive non-fluent aphasia
C9ORF72 CHMP2B GRN MAPT PSEN1 VCP

Limited systemic sclerosis
HLA-DRB1



Progressive non-fluent aphasia
Limited systemic sclerosis

Synonym(s):
- Agramatic variant of PPA
- Agramatic variant of primary progressive aphasia
- Non-fluent variant PPA

Synonym(s):
- Systemic sclerosis sine scleroderma

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare cardiac disease
- Rare renal disease
- Rare respiratory disease
- Rare skin disease
- Rare systemic or rheumatologic disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -

Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: -
Type of inheritance: sporadic

External references:
1 OMIM reference -
1 MeSH reference: D057178
External references:
No OMIM references
No MeSH references

No signs/symptoms info available.