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Primary peritoneal carcinoma

1 associated gene
9 signs/symptoms

PROTEIN INTERACTIONS: 2

Split hand-split foot malformation

6 OMIM references -
5 associated genes
9 signs/symptoms

Primary peritoneal carcinoma

Split hand-split foot malformation

BRCA1	(UniProt - OMIM)		BTRC	(UniProt - OMIM)
			FBXW4	(UniProt - OMIM)
			SHFM1	(UniProt - OMIM)
			TP63	(UniProt - OMIM)
			WNT10B	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	BRCA1 BRCA1	(0.63) (0.63)	SHFM1 TP63

Citations in the biomedical literature:

Primary peritoneal carcinoma		Split hand-split foot malformation
	Synonym(s): - EOPPC - Extra-ovarian primary peritoneal carcinoma - PPC - Primary peritoneal serous carcinoma - Serous surface papillary carcinoma		Synonym(s): - Ectrodactyly - Lobster-claw deformity - SHFM - Split hand foot malformation

	Classification (Orphanet): - Rare abdominal surgical disease - Rare oncologic disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: normal Type of inheritance: unknown		Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 6 OMIM references - No MeSH references

Primary peritoneal carcinoma		Split hand-split foot malformation
	Very frequent - Acute abdominal pain / colic - Anomalies of the abdominal wall - Constipation - Nausea / vomiting / regurgitation / merycism / hyperemesis - Neoplasms / tumors - Ovary / Fallopian tube neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma) - Peritoneal diseases - Weight loss / loss of appetite / break in weight curve / general health alteration Occasional - Early death / lethality		Very frequent - Autosomal dominant inheritance - Oligodactyly / ectrodactyly of fingers Frequent - Syndactyly of fingers / interdigital palm Occasional - Aniridia / iris hypoplasia - Autosomal recessive inheritance - Hand agenesis / absence - Sensorineural deafness / hearing loss - Trident hand / split hand / abnormal median ray - X-linked recessive inheritance