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Primary biliary cirrhosis
5 OMIM references -
8 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
Pyogenic bacterial infections due to MyD88 deficiency
1 OMIM reference -
1 associated gene
5 signs/symptoms
Primary biliary cirrhosis
Pyogenic bacterial infections due to MyD88 deficiency

IL12A
(UniProt - OMIM)
 MYD88
(UniProt - OMIM)
IL12RB1
(UniProt - OMIM)
IRF5
(UniProt - OMIM)
MMEL1
(UniProt)
POU2AF1
(UniProt - OMIM)
SPIB
(UniProt - OMIM)
TNFSF15
(UniProt - OMIM)
TNPO3
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
IRF5
(0.81)
MYD88


Citations in the biomedical literature:


Primary biliary cirrhosis
IL12A IL12RB1 IRF5 MMEL1 POU2AF1 SPIB
TNFSF15 TNPO3
Pyogenic bacterial infections due to MyD88 deficiency
MYD88



Primary biliary cirrhosis
Pyogenic bacterial infections due to MyD88 deficiency

Synonym(s):
- Hanot syndrome
Synonym(s):
- MyD88 deficiency
Classification (Orphanet):
- Rare hepatic disease
Classification (Orphanet):
- Rare genetic disease
- Rare immune disease
Classification (ICD10):
- Diseases of the digestive system -
Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: unknown
Average age onset: childhood
Average age of death: child / adolescent
Type of inheritance: autosomal recessive
External references:
5 OMIM references -
No MeSH references
External references:
1 OMIM reference -
No MeSH references
Pyogenic bacterial infections due to MyD88 deficiency

Very frequent
- Autosomal recessive inheritance
- Immunodeficiency / increased susceptibility to infections / recurrent infections

Frequent
- Chronic skin infection / ulcerations / ulcers / cancrum
- Nasal congestion / sinusitis / rhinitis / rhinorrhea

Occasional
- Fever / chilling


Primary biliary cirrhosis

(no data available)