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Primary biliary cirrhosis
5 OMIM references -
8 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
Beta-thalassemia - X-linked thrombocytopenia
1 OMIM reference -
1 associated gene
7 signs/symptoms
Primary biliary cirrhosis
Beta-thalassemia - X-linked thrombocytopenia

IL12A
(UniProt - OMIM)
 GATA1
(UniProt - OMIM)
IL12RB1
(UniProt - OMIM)
IRF5
(UniProt - OMIM)
MMEL1
(UniProt)
POU2AF1
(UniProt - OMIM)
SPIB
(UniProt - OMIM)
TNFSF15
(UniProt - OMIM)
TNPO3
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
SPIB
(0.56)
GATA1


Citations in the biomedical literature:


Primary biliary cirrhosis
IL12A IL12RB1 IRF5 MMEL1 POU2AF1 SPIB
TNFSF15 TNPO3
Beta-thalassemia - X-linked thrombocytopenia
GATA1



Primary biliary cirrhosis
Beta-thalassemia - X-linked thrombocytopenia

Synonym(s):
- Hanot syndrome
Synonym(s):
- XLTT
Classification (Orphanet):
- Rare hepatic disease
Classification (Orphanet):
- Rare genetic disease
- Rare hematologic disease
Classification (ICD10):
- Diseases of the digestive system -
Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: unknown
Average age onset: -
Average age of death: -
Type of inheritance: x-linked recessive
External references:
5 OMIM references -
No MeSH references
External references:
1 OMIM reference -
No MeSH references
Beta-thalassemia - X-linked thrombocytopenia

Very frequent
- Anaemia
- Hemoglobinosis / hemoglobinopathy
- Hemorrhage / hemorrhagic syndrome / excessive / long-lasting bleeding
- Platelets function anomaly
- Splenomegaly
- Thrombocytopenia / thrombopenia
- X-linked recessive inheritance



Primary biliary cirrhosis

(no data available)