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Muir-Torre syndrome

1 OMIM reference -
3 associated genes
14 signs/symptoms

PROTEIN INTERACTIONS: 2

Proximal spinal muscular atrophy type 4

1 OMIM reference -
2 associated genes
No signs/symptoms info

Muir-Torre syndrome

Proximal spinal muscular atrophy type 4

MLH1	(UniProt - OMIM)		SMN1	(UniProt - OMIM)
MSH2	(UniProt - OMIM)		SMN2	(UniProt - OMIM)
MSH6	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MSH2 MSH2	(0.63) (0.63)	SMN1 SMN2

Citations in the biomedical literature:

Muir-Torre syndrome		Proximal spinal muscular atrophy type 4
	Synonym(s): - Multiple keratoacanthoma, Muir-Torre type		Synonym(s): - SMA-IV - SMA4 - Spinal muscular atrophy, adult form

	Classification (Orphanet): - Rare eye disease - Rare gastroenterologic disease - Rare genetic disease - Rare oncologic disease - Rare skin disease		Classification (Orphanet): - Rare genetic disease - Rare neurologic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Diseases of the nervous system -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: - Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: 1-9 / 1 000 000 Average age onset: adulthood Average age of death: normal Type of inheritance: autosomal recessive

	External references: 1 OMIM reference - 1 MeSH reference: D055653		External references: 1 OMIM reference - No MeSH references

Muir-Torre syndrome
	Very frequent - Adenoma sebaceum - Autosomal dominant inheritance - Skin tumors / lumps / epidermal cysts Frequent - Colon neoplasm / tumor / carcinoma / cancer - Estomach / gastric neoplasm / tumor / carcinoma / cancer Occasional - Breast neoplasm / tumor / carcinoma / cancer - Hematologic / blood / lymphatic cancer - Hepatic / liver neoplasm / tumor / carcinoma / cancer - Kidney / renal neoplasm / tumor / carcinoma / cancer - Laryngeal neoplasm / tumor / carcinoma / cancer - Ovary / Fallopian tube neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma) - Salivary gland neoplasm / tumor / carcinoma / cancer - Ureteral / urethral / vesical / bladder neoplasm / tumor / carcinoma / cancer - Uterus / uterine / cervix / endometrium neoplasm / tumor / carcinoma / cancer
Proximal spinal muscular atrophy type 4
(no data available)