ODCs

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1 associated gene
No signs/symptoms info

PROTEIN INTERACTIONS: 1

6 OMIM references -
6 associated genes
3 signs/symptoms

Mendelian susceptibility to mycobacterial diseases due to complete ISG15 deficiency

Neuroblastoma


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	ISG15	(0.63)	TOP2A

Citations in the biomedical literature:

Mendelian susceptibility to mycobacterial diseases due to complete ISG15 deficiency		Neuroblastoma
	Synonym(s): - MSMD due to complete ISG15 deficiency		Synonym(s): - Neural crest tumor - Sympathoblastoma

	Classification (Orphanet): - Rare genetic disease - Rare immune disease		Classification (Orphanet): - Rare neurologic disease - Rare oncologic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Neoplasms -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: normal Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: 1-5 / 10 000 Average age onset: childhood Average age of death: child / adolescent Type of inheritance: sporadic

	External references: No OMIM references No MeSH references		External references: 6 OMIM references - 2 MeSH references: C536408 / D009447

Neuroblastoma
	Very frequent - Central nervous system / peripheral nerves neoplasm / tumor / carcinoma / cancer - Organic acid metabolism anomalies Frequent - Autosomal dominant inheritance
Mendelian susceptibility to mycobacterial diseases due to complete ISG15 deficiency
(no data available)