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Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations
1 OMIM reference -
1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 1
Aneurysm - osteoarthritis syndrome
1 OMIM reference -
1 associated gene
No signs/symptoms info
Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations
Aneurysm - osteoarthritis syndrome

BRCA2
(UniProt - OMIM)
 SMAD3
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
BRCA2
(0.79)
SMAD3


Citations in the biomedical literature:


Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations
BRCA2
Aneurysm - osteoarthritis syndrome
SMAD3



Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutations
Aneurysm - osteoarthritis syndrome

Synonym(s):
(no synonyms)

Synonym(s):
- AOS
- Loeys-Dietz syndrome with osteoarthritis
Classification (Orphanet):
- Rare genetic disease
- Rare oncologic disease
- Rare renal disease
Classification (Orphanet):
- Rare circulatory system disease
- Rare genetic disease
- Rare surgical thoracic disease
- Rare systemic or rheumatologic disease
Classification (ICD10):
(no data available)
Classification (ICD10):
(no data available)
Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: variable
Average age of death: -
Type of inheritance: autosomal dominant
External references:
1 OMIM reference -
No MeSH references
External references:
1 OMIM reference -
No MeSH references
No signs/symptoms info available.