ODCs

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1 OMIM reference -
2 associated genes
6 signs/symptoms

PROTEIN INTERACTIONS: 1

2 OMIM references -
2 associated genes
No signs/symptoms info

Dermatofibrosarcoma protuberans

Nodulosis-arthropathy-osteolysis syndrome

COL1A1	(UniProt - OMIM)		MMP14	(UniProt - OMIM)
PDGFB	(UniProt - OMIM)		MMP2	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	COL1A1	(0.85)	MMP2

Citations in the biomedical literature:

Dermatofibrosarcoma protuberans		Nodulosis-arthropathy-osteolysis syndrome
	Synonym(s): - DFSP		Synonym(s): - Multicentric osteolysis - nodulosis - arthropathy - NAO syndrome

	Classification (Orphanet): - Rare genetic disease - Rare oncologic disease - Rare skin disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease

	Classification (ICD10): (no data available)		Classification (ICD10): - Diseases of the musculoskeletal system and connective tissue -

	Epidemiological data: Class of prevalence: 1-5 / 10 000 Average age onset: variable Average age of death: adult Type of inheritance: sporadic		Epidemiological data: (no data available)

	External references: 1 OMIM reference - 1 MeSH reference: C538219		External references: 2 OMIM references - No MeSH references

Dermatofibrosarcoma protuberans
	Very frequent - Erythema / erythematous lesions / erythroderma / polymorphous erythema - Skin / cutaneous neoplasm / tumor / carcinoma / cancer (excluding melanoma) - Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma - Subcutaneous nodules / lipomas / tumefaction / swelling - Thick skin / pachydermia / orange skin Frequent - Chronic skin infection / ulcerations / ulcers / cancrum
Nodulosis-arthropathy-osteolysis syndrome
(no data available)