ODCs

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1 OMIM reference -
2 associated genes
6 signs/symptoms

PROTEIN INTERACTIONS: 1

1 associated gene
3 signs/symptoms

Dermatofibrosarcoma protuberans

Centripetalis recessive dystrophic epidermolysis bullosa

COL1A1	(UniProt - OMIM)		COL7A1	(UniProt - OMIM)
PDGFB	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	COL1A1	(0.75)	COL7A1

Citations in the biomedical literature:

Dermatofibrosarcoma protuberans		Centripetalis recessive dystrophic epidermolysis bullosa
	Synonym(s): - DFSP		Synonym(s): - Centripetal dystrophic epidermolysis bullosa - Centripetal recessive dystrophic epidermolysis bullosa - RDEB, centripetalis - RDEB-Ce

	Classification (Orphanet): - Rare genetic disease - Rare oncologic disease - Rare skin disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare genetic disease - Rare skin disease

	Classification (ICD10): (no data available)		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: 1-5 / 10 000 Average age onset: variable Average age of death: adult Type of inheritance: sporadic		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal recessive

	External references: 1 OMIM reference - 1 MeSH reference: C538219		External references: No OMIM references No MeSH references

Dermatofibrosarcoma protuberans		Centripetalis recessive dystrophic epidermolysis bullosa
	Very frequent - Erythema / erythematous lesions / erythroderma / polymorphous erythema - Skin / cutaneous neoplasm / tumor / carcinoma / cancer (excluding melanoma) - Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma - Subcutaneous nodules / lipomas / tumefaction / swelling - Thick skin / pachydermia / orange skin Frequent - Chronic skin infection / ulcerations / ulcers / cancrum		Very frequent - Autosomal recessive inheritance - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment Frequent - Follicular / erythematous / edematous papules / milium