Day 1: The protein structure universe, resources and visualization

Slides

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Exercises

This sequence corresponds to an inactive mutant of an enzyme found during your research work.

1. Find all solved structures for that enzime. Choose one of them to continue your analysis taking into account quality parameters (check a pair of structures with validation software or databases)

2. Generate a high-quality image for a publication highlighting the structural explanation for that loss of function.
You might have a look at Creating an eye-catching figure with Pymol.

Resources

Protein structure resources

Other PDB portal sites

Validation software

Visualization software