Untitled Project

Created: May 8, 2024, 11:09 a.m. at 11:09

Models Name Description GMQE QSQE Seq Id Coverage Range Method Resolution Oligo-state Ligands Found by Seq Similarity
P46969.1.A
Ribulose-phosphate 3-epimerase
AlphaFold DB model of RPE_YEAST (gene: RPE1, organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast))
 0.98 100.00 1.00 1-238 AlphaFold v2 -1.00 monomer AFDB search 0.62
✓
 3ovp.1.A
Ribulose-phosphate 3-epimerase
Crystal Structure of hRPE
 0.86 0.78 55.75 0.95 1-237 X-ray 1.70 homo-dimer 2 x FE2, 6 x XPE HHblits 0.46
✓
 3ovq.1.B
Ribulose-phosphate 3-epimerase
Crystal Structure of hRPE and D-Ribulose-5-Phospate Complex
 0.85 0.78 55.75 0.95 1-237 X-ray 2.00 homo-dimer 2 x FE2, 2 x 5RP, 7 x XPE HHblits 0.46
✓
 3ovp.1.A
Ribulose-phosphate 3-epimerase
Crystal Structure of hRPE
 0.84 0.77 57.27 0.92 6-236 X-ray 1.70 homo-dimer 2 x FE2, 6 x XPE BLAST 0.47
3ovq.1.B
Ribulose-phosphate 3-epimerase
Crystal Structure of hRPE and D-Ribulose-5-Phospate Complex
 0.84 0.76 57.27 0.92 6-236 X-ray 2.00 homo-dimer 2 x FE2, 2 x 5RP, 7 x XPE BLAST 0.47
3qc3.1.A
D-ribulose-5-phosphate-3-epimerase
Crystal structure of a D-ribulose-5-phosphate-3-epimerase (NP_954699) from HOMO SAPIENS at 2.20 A resolution
 0.85 0.75 56.11 0.93 1-232 X-ray 2.20 homo-dimer 2 x ZN, 2 x NI, 2 x FE HHblits 0.46
3qc3.1.A
D-ribulose-5-phosphate-3-epimerase
Crystal structure of a D-ribulose-5-phosphate-3-epimerase (NP_954699) from HOMO SAPIENS at 2.20 A resolution
 0.84 0.74 57.34 0.92 6-234 X-ray 2.20 homo-dimer 2 x ZN, 2 x NI, 2 x FE BLAST 0.47
4nu7.1.A
Ribulose-phosphate 3-epimerase
2.05 Angstrom Crystal Structure of Ribulose-phosphate 3-epimerase from Toxoplasma gondii.
 0.81 0.68 54.13 0.92 2-231 X-ray 2.05 homo-dimer 2 x ZN HHblits 0.46
1h1z.1.A
D-RIBULOSE-5-PHOSPHATE 3-EPIMERASE
THE STRUCTURE OF THE CYTOSOLIC D-RIBULOSE-5-PHOSPHATE 3-EPIMERASE FROM RICE COMPLEXED WITH SULFATE AND ZINC
 0.82 0.71 53.00 0.91 2-231 X-ray 3.40 homo-dimer 2 x ZN HHblits 0.46
4nu7.1.A
Ribulose-phosphate 3-epimerase
2.05 Angstrom Crystal Structure of Ribulose-phosphate 3-epimerase from Toxoplasma gondii.
 0.80 0.66 55.35 0.90 2-228 X-ray 2.05 homo-dimer 2 x ZN BLAST 0.46
1h1z.1.A
D-RIBULOSE-5-PHOSPHATE 3-EPIMERASE
THE STRUCTURE OF THE CYTOSOLIC D-RIBULOSE-5-PHOSPHATE 3-EPIMERASE FROM RICE COMPLEXED WITH SULFATE AND ZINC
 0.79 0.68 55.50 0.88 6-227 X-ray 3.40 homo-dimer 2 x ZN BLAST 0.47
1tqx.1.A
D-ribulose-5-phosphate 3-epimerase, putative
Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum
 0.77 0.00 51.16 0.90 2-233 X-ray 2.00 monomer 1 x ZN BLAST 0.44
1tqx.1.A
D-ribulose-5-phosphate 3-epimerase, putative
Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum
 0.79 0.00 48.85 0.91 1-231 X-ray 2.00 monomer 1 x ZN HHblits 0.43
7sbj.1.A
Ribulose-phosphate 3-epimerase
Crystal Structure of Ribulose-phosphate 3-epimerase from Stenotrophomonas maltophilia K279a
 0.74 0.30 40.83 0.92 1-230 X-ray 1.85 homo-trimer 3 x ZN, 1 x MG HHblits 0.40
1tqj.1.A
Ribulose-phosphate 3-epimerase
Crystal structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 angstrom resolution
 0.68 0.37 45.28 0.89 5-230 X-ray 1.60 homo-hexamer BLAST 0.42
1tqj.1.A
Ribulose-phosphate 3-epimerase
Crystal structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 angstrom resolution
 0.73 0.35 41.74 0.92 1-231 X-ray 1.60 homo-hexamer HHblits 0.40
5umf.1.A
Ribulose-phosphate 3-epimerase
Crystal Structure of a Ribulose-phosphate 3-epimerase from Neisseria gonorrhoeae with bound phosphate
 0.73 0.38 41.94 0.91 1-230 X-ray 1.40 homo-hexamer 6 x ZN HHblits 0.40
7b1w.1.A
Ribulose-phosphate 3-epimerase
Crystal structure of plastidial ribulose epimerase RPE1 from the model alga Chlamydomonas reinhardtii
 0.73 0.38 41.20 0.91 2-230 X-ray 1.94 homo-hexamer 6 x ZN HHblits 0.40
2fli.1.A
ribulose-phosphate 3-epimerase
The crystal structure of D-ribulose 5-phosphate 3-epimerase from Streptococus pyogenes complexed with D-xylitol 5-phosphate
 0.75 0.44 41.86 0.90 1-228 X-ray 1.80 homo-hexamer 6 x ZN, 6 x DX5 HHblits 0.40
7u5y.1.A
Ribulose-phosphate 3-epimerase
Crystal structure of ribulose-phosphate 3-epimerase from Pseudomonas aeruginosa
 0.73 0.37 40.74 0.91 3-230 X-ray 2.55 homo-hexamer 6 x ZN HHblits 0.40
7sbj.1.A
Ribulose-phosphate 3-epimerase
Crystal Structure of Ribulose-phosphate 3-epimerase from Stenotrophomonas maltophilia K279a
 0.71 0.28 41.98 0.89 5-228 X-ray 1.85 homo-trimer 3 x ZN, 1 x MG BLAST 0.41
1rpx.1.A
PROTEIN (RIBULOSE-PHOSPHATE 3-EPIMERASE)
D-RIBULOSE-5-PHOSPHATE 3-EPIMERASE FROM SOLANUM TUBEROSUM CHLOROPLASTS
 0.72 0.38 40.00 0.90 2-229 X-ray 2.30 homo-hexamer HHblits 0.40
3inp.1.A
D-ribulose-phosphate 3-epimerase
2.05 Angstrom Resolution Crystal Structure of D-ribulose-phosphate 3-epimerase from Francisella tularensis.
 0.71 0.08 38.43 0.91 1-228 X-ray 2.05 homo-12-mer HHblits 0.39
7u5y.1.A
Ribulose-phosphate 3-epimerase
Crystal structure of ribulose-phosphate 3-epimerase from Pseudomonas aeruginosa
 0.72 0.34 41.51 0.89 6-229 X-ray 2.55 homo-hexamer 6 x ZN BLAST 0.40
7b1w.1.A
Ribulose-phosphate 3-epimerase
Crystal structure of plastidial ribulose epimerase RPE1 from the model alga Chlamydomonas reinhardtii
 0.69 0.40 45.63 0.87 5-224 X-ray 1.94 homo-hexamer 6 x ZN BLAST 0.42
5umf.1.A
Ribulose-phosphate 3-epimerase
Crystal Structure of a Ribulose-phosphate 3-epimerase from Neisseria gonorrhoeae with bound phosphate
 0.72 0.36 43.13 0.89 6-229 X-ray 1.40 homo-hexamer 6 x ZN BLAST 0.41
3inp.1.A
D-ribulose-phosphate 3-epimerase
2.05 Angstrom Resolution Crystal Structure of D-ribulose-phosphate 3-epimerase from Francisella tularensis.
 0.71 0.05 39.15 0.89 6-229 X-ray 2.05 homo-12-mer BLAST 0.40
1rpx.1.A
PROTEIN (RIBULOSE-PHOSPHATE 3-EPIMERASE)
D-RIBULOSE-5-PHOSPHATE 3-EPIMERASE FROM SOLANUM TUBEROSUM CHLOROPLASTS
 0.70 0.40 44.17 0.87 5-224 X-ray 2.30 homo-hexamer BLAST 0.42
3ct7.1.A
D-allulose-6-phosphate 3-epimerase
Crystal structure of D-allulose 6-phosphate 3-epimerase from Escherichia Coli K-12
 0.68 32.56 0.90 4-232 X-ray 2.50 homo-hexamer 6 x MG HHblits 0.37
2fli.1.A
ribulose-phosphate 3-epimerase
The crystal structure of D-ribulose 5-phosphate 3-epimerase from Streptococus pyogenes complexed with D-xylitol 5-phosphate
 0.69 0.41 46.19 0.83 6-215 X-ray 1.80 homo-hexamer 6 x ZN, 6 x DX5 BLAST 0.42
3ct7.1.A
D-allulose-6-phosphate 3-epimerase
Crystal structure of D-allulose 6-phosphate 3-epimerase from Escherichia Coli K-12
 0.62 0.33 36.84 0.80 6-209 X-ray 2.50 homo-hexamer 6 x MG BLAST 0.39
1wxj.1.A
tryptophan synthase alpha chain
Crystal Structure Of Tryptophan Synthase A-Subunit with Indole-3-propanol phosphate From Thermus Thermophilus Hb8
 0.46 18.40 0.89 3-233 X-ray 1.70 monomer 1 x IPL HHblits 0.30
3cu2.1.A
Ribulose-5-phosphate 3-epimerase
Crystal structure of ribulose-5-phosphate 3-epimerase (YP_718263.1) from Haemophilus somnus 129PT at 1.91 A resolution
 0.56 19.05 0.88 2-227 X-ray 1.91 homo-dimer 2 x CA, 2 x NI HHblits 0.30
3nq6.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant P180A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor 6-azaUMP
 0.41 18.40 0.89 2-231 X-ray 1.49 homo-dimer 2 x UP6 HHblits 0.28
3sj3.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant R160A.Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.41 18.87 0.89 2-231 X-ray 1.26 homo-dimer 2 x BMP HHblits 0.28
5kin.1.A
Tryptophan synthase alpha chain
Crystal structure of tryptophan synthase alpha beta complex from Streptococcus pneumoniae
 0.40 15.64 0.89 3-229 X-ray 2.45 hetero-2-2-mer HHblits 0.29
4fx6.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.41 18.40 0.89 2-231 X-ray 1.53 homo-dimer 2 x BMP HHblits 0.28
6qky.1.A
Tryptophan synthase alpha chain
Tryptophan synthase subunit alpha from Streptococcus pneumoniae with 3D domain swap in the core of TIM barrel
 0.40 15.64 0.89 3-229 X-ray 2.54 homo-dimer HHblits 0.29
6qky.1.B
Tryptophan synthase alpha chain
Tryptophan synthase subunit alpha from Streptococcus pneumoniae with 3D domain swap in the core of TIM barrel
 0.40 15.64 0.89 3-229 X-ray 2.54 homo-dimer HHblits 0.29
6qky.3.A
Tryptophan synthase alpha chain
Tryptophan synthase subunit alpha from Streptococcus pneumoniae with 3D domain swap in the core of TIM barrel
 0.39 15.64 0.89 3-229 X-ray 2.54 homo-dimer HHblits 0.29
6qky.3.B
Tryptophan synthase alpha chain
Tryptophan synthase subunit alpha from Streptococcus pneumoniae with 3D domain swap in the core of TIM barrel
 0.41 15.64 0.89 3-229 X-ray 2.54 homo-dimer HHblits 0.29
6qky.5.A
Tryptophan synthase alpha chain
Tryptophan synthase subunit alpha from Streptococcus pneumoniae with 3D domain swap in the core of TIM barrel
 0.40 15.64 0.89 3-229 X-ray 2.54 homo-dimer HHblits 0.29
3qmt.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.41 18.96 0.89 2-231 X-ray 1.32 homo-dimer 2 x BMP HHblits 0.28
3lts.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A,I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.41 18.01 0.89 2-231 X-ray 1.43 homo-dimer 2 x BMP HHblits 0.28
3m5x.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A,I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.40 18.01 0.89 2-231 X-ray 1.40 homo-dimer HHblits 0.28
1klz.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Crystal structure of orotidine monophosphate decarboxylase mutant D70A complexed with UMP
 0.38 0.04 19.05 0.88 2-233 X-ray 1.50 homo-dimer 2 x U HHblits 0.29
3qf0.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant T159V,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.39 0.20 20.57 0.88 1-231 X-ray 1.34 homo-dimer 2 x BMP HHblits 0.29
3qez.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant T159V,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.41 0.19 18.48 0.89 2-231 X-ray 1.54 homo-dimer 2 x BMP HHblits 0.28
3qms.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant T159V,V182A,Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.41 0.21 18.96 0.89 2-231 X-ray 1.32 homo-dimer 2 x BMP HHblits 0.28
3sec.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate
 0.38 0.18 19.52 0.88 2-233 X-ray 1.70 homo-dimer 2 x PFU HHblits 0.28
3pbu.1.A
Orotidine 5'-monophosphate decarboxylase
Crystal structure of the mutant I96S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate
 0.39 0.20 19.62 0.88 1-231 X-ray 1.30 homo-dimer 2 x UP6 HHblits 0.29
1kly.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Orotidine monophosphate decarboxylase D70G mutant complexed with 6-azaUMP
 0.37 0.02 19.05 0.88 2-233 X-ray 1.50 homo-dimer 2 x UP6 HHblits 0.28
3m1z.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A.V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.41 0.20 19.05 0.88 2-231 X-ray 1.42 homo-dimer 2 x BMP HHblits 0.28
3m5y.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A,V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.40 0.20 19.05 0.88 2-231 X-ray 1.45 homo-dimer HHblits 0.28
1km0.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Crystal structure of orotidine monophosphate decarboxylase mutant D70N complexed with 6-azaUMP
 0.38 0.17 19.05 0.88 2-233 X-ray 1.70 homo-dimer 2 x UP6 HHblits 0.28
1km0.1.B
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Crystal structure of orotidine monophosphate decarboxylase mutant D70N complexed with 6-azaUMP
 0.37 0.16 19.05 0.88 2-233 X-ray 1.70 homo-dimer 2 x UP6 HHblits 0.28
3nqf.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant L123S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.39 19.14 0.88 2-231 X-ray 1.31 homo-dimer 2 x BMP HHblits 0.29
3p60.1.A
Orotidine 5'-monophosphate decarboxylase
Crystal structure of the mutant T159V of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.39 0.18 19.62 0.88 2-232 X-ray 1.40 homo-dimer 2 x BMP HHblits 0.29
3p61.1.A
Orotidine 5'-monophosphate decarboxylase
Crystal structure of the mutant R160A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.41 18.57 0.88 2-231 X-ray 1.40 homo-dimer 2 x BMP HHblits 0.28
3li1.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.39 19.62 0.88 2-232 X-ray 1.35 homo-dimer 2 x BMQ HHblits 0.29
3m47.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.39 19.62 0.88 2-232 X-ray 1.20 homo-dimer HHblits 0.29
3nqe.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant L123N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.40 19.14 0.88 2-231 X-ray 1.42 homo-dimer 2 x BMP HHblits 0.29
4lw7.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.39 19.14 0.88 2-232 X-ray 1.42 homo-dimer 2 x BMP HHblits 0.29
3rlv.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant Y206F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.38 20.19 0.87 2-231 X-ray 1.42 homo-dimer 2 x BMP HHblits 0.29
4lc8.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant H128N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.39 19.23 0.87 2-231 X-ray 1.32 homo-dimer 2 x BMP, 1 x MG HHblits 0.29
3lv6.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant I218F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 20.19 0.87 2-231 X-ray 1.45 homo-dimer 2 x BMP HHblits 0.29
2zz3.1.A
Orotidine 5'-phosphate decarboxylase
Covalent complex of orotidine monophosphate decarboxylase D70A mutant from M. thermoautotrophicus with 6-cyano-UMP
 0.38 18.57 0.88 2-233 X-ray 1.80 homo-dimer 2 x 6CN HHblits 0.28
3g1h.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate
 0.39 19.71 0.87 2-231 X-ray 2.30 homo-dimer 2 x H2U HHblits 0.29
3g18.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.39 19.71 0.87 2-231 X-ray 1.60 homo-dimer HHblits 0.29
3g1h.6.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate
 0.39 19.71 0.87 2-231 X-ray 2.30 homo-dimer 2 x H2U HHblits 0.29
3g1f.5.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5,6-dihydroorotidine 5'-monophosphate
 0.39 19.71 0.87 2-231 X-ray 2.50 homo-dimer 2 x 2OM HHblits 0.29
3nqg.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V155D of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.39 19.71 0.87 2-231 X-ray 1.42 homo-dimer 2 x BMP HHblits 0.29
3lty.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A,I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.40 18.10 0.88 3-232 X-ray 1.50 homo-dimer 2 x BMP HHblits 0.28
3m5z.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A,I218A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.39 18.10 0.88 3-232 X-ray 1.35 homo-dimer HHblits 0.28
3qmr.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant R160A,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.42 0.22 18.66 0.88 2-231 X-ray 1.32 homo-dimer 2 x BMP HHblits 0.28
1km3.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
crystal structure of ODCase mutant K42A complexed with 6-azaUMP
 0.38 19.62 0.88 1-233 X-ray 1.50 homo-dimer 2 x UP6 HHblits 0.28
3lhz.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 20.19 0.87 2-231 X-ray 1.40 homo-dimer 2 x BMQ HHblits 0.29
3m44.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.38 20.19 0.87 2-231 X-ray 1.40 homo-dimer HHblits 0.29
1km1.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Orotidine monophosphate decarboxylase mutant S127A crystal structure
 0.38 19.23 0.87 2-231 X-ray 1.60 homo-dimer 2 x UP6 HHblits 0.29
4gc4.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant R160A.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.40 18.18 0.88 3-231 X-ray 1.42 homo-dimer 2 x BMP HHblits 0.28
1km5.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Crystal structure of ODCase mutant D75N complexed with 6-azaUMP
 0.37 19.71 0.87 2-231 X-ray 1.50 homo-dimer 2 x UP6 HHblits 0.29
3p5z.1.A
Orotidine 5'-monophosphate decarboxylase
Crystal structure of the mutant T159S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 20.29 0.87 2-232 X-ray 1.30 homo-dimer 2 x BMP, 2 x POL HHblits 0.29
2zz4.1.A
Orotidine 5'-phosphate decarboxylase
Covalent complex of orotidine monophosphate decarboxylase D75N mutant from M. thermoautotrophicum with 6-cyano-UMP
 0.39 19.14 0.88 2-232 X-ray 1.67 homo-dimer 2 x 6CN HHblits 0.28
3v1p.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant Q185A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.38 19.71 0.87 2-231 X-ray 1.37 homo-dimer 2 x BMP HHblits 0.29
3siz.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.38 19.23 0.87 2-231 X-ray 1.32 homo-dimer 2 x BMP HHblits 0.29
1km4.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
crystal structure of ODCase mutant K72A complexed with UMP
 0.37 19.71 0.87 2-233 X-ray 1.50 homo-dimer 2 x U HHblits 0.29
1dvj.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
CRYSTAL STRUCTURE OF OROTIDINE MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 6-AZAUMP
 0.39 19.23 0.87 3-232 X-ray 1.50 homo-dimer 2 x UP6 HHblits 0.28
1km2.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
crystal structure of orotidine monophosphate mutant Q185A with 6-azaUMP
 0.37 19.71 0.87 2-231 X-ray 1.50 homo-dimer 2 x UP6 HHblits 0.28
3lht.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V201F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 19.71 0.87 2-231 X-ray 1.35 homo-dimer 2 x BMQ HHblits 0.28
3g1s.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant D70G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.37 19.23 0.87 2-231 X-ray 1.40 homo-dimer HHblits 0.28
3g1v.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant D70G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 5-fluorouridine 5'-monophosphate
 0.37 19.23 0.87 2-231 X-ray 1.30 homo-dimer 2 x 5FU HHblits 0.28
2e6y.1.A
Orotidine 5'-phosphate decarboxylase
Covalent complex of orotidine 5'-monophosphate decarboxylase (ODCase) with 6-Iodo-UMP
 0.38 19.23 0.87 2-231 X-ray 1.60 homo-dimer 2 x U5P HHblits 0.28
3exr.1.A
RmpD (Hexulose-6-phosphate synthase)
Crystal structure of KGPDC from Streptococcus mutans
 0.42 18.27 0.87 2-230 X-ray 1.70 homo-dimer HHblits 0.28
3exs.1.A
RmpD (Hexulose-6-phosphate synthase)
Crystal structure of KGPDC from Streptococcus mutans in complex with D-R5P
 0.42 18.27 0.87 2-230 X-ray 2.50 homo-dimer 1 x 5RP HHblits 0.28
3exs.2.B
RmpD (Hexulose-6-phosphate synthase)
Crystal structure of KGPDC from Streptococcus mutans in complex with D-R5P
 0.43 18.27 0.87 2-230 X-ray 2.50 homo-dimer 1 x 5RP HHblits 0.28
3m43.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.38 19.23 0.87 2-231 X-ray 1.30 homo-dimer HHblits 0.28
3lhy.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant I199A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 19.23 0.87 2-231 X-ray 1.40 homo-dimer 2 x BMQ HHblits 0.28
1km6.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Crystal structure of ODCase mutant D70AK72A complexed with OMP
 0.37 19.14 0.88 2-233 X-ray 1.50 homo-dimer 2 x OMP HHblits 0.28
3lld.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant S127G of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate
 0.38 18.75 0.87 3-232 X-ray 1.45 homo-dimer 2 x UP6 HHblits 0.28
4lc6.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant H128Q of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.38 19.81 0.87 2-232 X-ray 1.32 homo-dimer 2 x BMP HHblits 0.29
3rlu.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant K82A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP
 0.38 19.23 0.87 2-231 X-ray 1.49 homo-dimer 2 x BMP HHblits 0.28
2zz2.1.B
Orotidine 5'-phosphate decarboxylase
Orotidine Monophosphate Decarboxylase K72A mutant from M. thermoautotrophicum complexed with 6-cyano-UMP
 0.38 19.23 0.87 2-233 X-ray 1.53 homo-dimer 2 x 6CN HHblits 0.28
1dv7.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
CRYSTAL STRUCTURE OF OROTIDINE MONOPHOSPHATE DECARBOXYLASE
 0.38 19.32 0.87 3-231 X-ray 1.80 homo-dimer HHblits 0.29
3lhu.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant I199F of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 19.32 0.87 2-232 X-ray 1.60 homo-dimer 2 x BMQ HHblits 0.29
3lv5.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant I199E of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 18.84 0.87 3-231 X-ray 1.44 homo-dimer 2 x BMP HHblits 0.29
3p5y.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant T159A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.36 19.90 0.87 2-231 X-ray 1.60 homo-dimer 2 x BMP HHblits 0.29
3pc0.1.A
Orotidine 5'-monophosphate decarboxylase
Crystal structure of the mutant V155S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate
 0.38 19.32 0.87 3-231 X-ray 1.30 homo-dimer 2 x UP6 HHblits 0.29
3lhw.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.40 0.20 18.27 0.87 2-231 X-ray 1.35 homo-dimer 2 x BMQ HHblits 0.28
3m41.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum
 0.39 0.18 18.27 0.87 2-231 X-ray 1.40 homo-dimer HHblits 0.28
3llf.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant S127P of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate
 0.38 18.84 0.87 3-231 X-ray 1.30 homo-dimer 2 x UP6 HHblits 0.28
3nq7.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant F71A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 19.90 0.87 2-231 X-ray 1.44 homo-dimer 2 x BMP HHblits 0.29
3pbv.1.A
Orotidine 5'-monophosphate decarboxylase
Crystal structure of the mutant I96T of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate
 0.39 20.39 0.87 2-231 X-ray 1.30 homo-dimer 2 x UP6 HHblits 0.29
3tha.1.A
Tryptophan synthase alpha chain
Tryptophan synthase subunit alpha from Campylobacter jejuni.
 0.41 15.87 0.87 3-226 X-ray 2.37 homo-dimer HHblits 0.28
3tha.1.B
Tryptophan synthase alpha chain
Tryptophan synthase subunit alpha from Campylobacter jejuni.
 0.42 15.87 0.87 3-226 X-ray 2.37 homo-dimer HHblits 0.28
1so6.1.A
3-keto-L-gulonate 6-phosphate decarboxylase
Crystal structure of E112Q/H136A double mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
 0.48 0.23 14.69 0.89 1-230 X-ray 1.90 homo-dimer 2 x MG, 2 x TX4 HHblits 0.27
3nqa.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant F100A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.39 19.90 0.87 2-231 X-ray 1.39 homo-dimer 2 x BMP HHblits 0.29
4fx8.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant Q185A.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 19.90 0.87 2-231 X-ray 1.94 homo-dimer 2 x BMP HHblits 0.29
4fx8.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant Q185A.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.37 19.90 0.87 2-231 X-ray 1.94 homo-dimer 2 x BMP HHblits 0.29
3g22.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant D70N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with uridine 5'-monophosphate
 0.38 18.84 0.87 3-231 X-ray 1.50 homo-dimer 2 x U HHblits 0.28
3g1y.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant D70N of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with sulfate
 0.37 18.84 0.87 3-231 X-ray 1.40 homo-dimer HHblits 0.28
3lhv.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant V182A.I199A.V201A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.39 17.79 0.87 3-231 X-ray 1.35 homo-dimer 2 x BMQ HHblits 0.28
2zz5.1.A
Orotidine 5'-phosphate decarboxylase
Orotidine Monophosphate Deacarboxylase D70A/K72A double mutant from M. thermoautotrophicum complexed with 6- cyano-UMP
 0.36 18.27 0.87 3-231 X-ray 1.56 homo-dimer 2 x 6CN HHblits 0.28
4fxr.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant T159V.R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 19.90 0.87 2-231 X-ray 1.71 homo-dimer 2 x BMP HHblits 0.29
1lol.1.A
orotidine 5'-monophosphate decarboxylase
Crystal structure of orotidine monophosphate decarboxylase complex with XMP
 0.37 19.42 0.87 3-232 X-ray 1.90 homo-dimer 2 x BU2, 2 x XMP HHblits 0.29
1lol.1.B
orotidine 5'-monophosphate decarboxylase
Crystal structure of orotidine monophosphate decarboxylase complex with XMP
 0.39 19.42 0.87 3-232 X-ray 1.90 homo-dimer 2 x BU2, 2 x XMP HHblits 0.29
1so3.1.A
3-keto-L-gulonate 6-phosphate decarboxylase
Crystal structure of H136A mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
 0.49 0.18 14.22 0.89 1-230 X-ray 1.90 homo-dimer 2 x MG, 2 x TX4 HHblits 0.27
5ey5.1.A
LBCATS-a
LBCATS
 0.43 20.00 0.84 3-217 X-ray 1.97 hetero-2-2-mer 2 x G3P, 2 x PLP HHblits 0.31
5ey5.1.C
LBCATS-a
LBCATS
 0.43 20.00 0.84 3-217 X-ray 1.97 hetero-2-2-mer 2 x G3P, 2 x PLP HHblits 0.31
1los.1.A
orotidine monophosphate decarboxylase
crystal structure of orotidine monophosphate decarboxylase mutant deltaR203A complexed with 6-azaUMP
 0.38 18.36 0.87 3-231 X-ray 1.90 homo-dimer 2 x UP6 HHblits 0.28
1los.2.A
orotidine monophosphate decarboxylase
crystal structure of orotidine monophosphate decarboxylase mutant deltaR203A complexed with 6-azaUMP
 0.34 18.36 0.87 3-231 X-ray 1.90 homo-dimer 2 x UP6 HHblits 0.28
1so4.1.A
3-keto-L-gulonate 6-phosphate decarboxylase
Crystal structure of K64A mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
 0.49 0.18 14.22 0.89 1-230 X-ray 1.70 homo-dimer 2 x MG, 2 x TX4 HHblits 0.27
1so5.1.A
3-keto-L-gulonate 6-phosphate decarboxylase
Crystal structure of E112Q mutant of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate
 0.48 0.16 15.24 0.88 1-230 X-ray 1.80 homo-dimer 2 x MG, 2 x TX4 HHblits 0.27
1xby.1.A
3-keto-L-gulonate 6-phosphate decarboxylase
Structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/T169A mutant with bound D-ribulose 5-phosphate
 0.48 0.21 15.24 0.88 1-230 X-ray 1.58 homo-dimer 2 x 5RP, 2 x MG HHblits 0.27
3li0.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
 0.38 20.00 0.86 3-231 X-ray 1.50 homo-dimer 2 x BMQ HHblits 0.29
1xbx.1.A
3-keto-L-gulonate 6-phosphate decarboxylase
Structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/R139V/T169A mutant with bound D-ribulose 5-phosphate
 0.48 14.76 0.88 1-229 X-ray 1.81 homo-dimer 1 x HMS, 2 x MG, 1 x 5RP HHblits 0.27
3f4w.1.A
Putative hexulose 6 phosphate synthase
The 1.65A Crystal Structure of 3-hexulose-6-phosphate synthase from Salmonella typhimurium
 0.49 16.99 0.87 4-229 X-ray 1.65 homo-dimer HHblits 0.28
3ieb.1.A
Hexulose-6-phosphate synthase SgbH
Crystal structure of 3-keto-L-gulonate-6-phosphate decarboxylase from Vibrio cholerae O1 biovar El Tor str. N16961
 0.46 15.46 0.87 4-230 X-ray 2.10 homo-dimer HHblits 0.28
1jjk.5.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Selenomethionine Substitution of Orotidine-5'-monophosphate Decarboxylase from E. coli Causes a Change in Crystal Contacts and Space Group
 0.38 16.91 0.87 4-229 X-ray 3.00 homo-dimer 2 x BMP HHblits 0.28
1l2u.1.A
Orotidine 5'-phosphate decarboxylase
Orotidine 5'-monophosphate decarboxylase from E. coli
 0.39 16.91 0.87 4-229 X-ray 2.50 homo-dimer HHblits 0.28
2yyt.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of uncharacterized conserved protein from Geobacillus kaustophilus
 0.37 19.42 0.87 7-234 X-ray 2.30 homo-dimer HHblits 0.28
2yyu.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of uncharacterized conserved protein from Geobacillus kaustophilus
 0.38 19.42 0.87 7-234 X-ray 2.20 homo-dimer 2 x C5P HHblits 0.28
2yyu.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of uncharacterized conserved protein from Geobacillus kaustophilus
 0.38 19.42 0.87 7-234 X-ray 2.20 homo-dimer 2 x C5P HHblits 0.28
1q6r.1.B
3-keto-L-gulonate 6-phosphate decarboxylase
Structure of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-xylulose 5-phosphate
 0.48 13.81 0.88 2-230 X-ray 1.76 homo-dimer 2 x MG, 2 x LX1 HHblits 0.26
1loq.1.A
orotidine 5'-monophosphate decarboxylase
Crystal structure of orotidine monophosphate decarboxylase complexed with product UMP
 0.37 19.61 0.86 4-231 X-ray 1.50 homo-dimer 2 x U HHblits 0.29
3tr2.1.A
Orotidine 5'-phosphate decarboxylase
Structure of a orotidine 5'-phosphate decarboxylase (pyrF) from Coxiella burnetii
 0.37 16.59 0.86 2-229 X-ray 2.00 homo-dimer HHblits 0.28
3tr2.1.B
Orotidine 5'-phosphate decarboxylase
Structure of a orotidine 5'-phosphate decarboxylase (pyrF) from Coxiella burnetii
 0.39 16.59 0.86 2-229 X-ray 2.00 homo-dimer HHblits 0.28
3ru6.1.A
Orotidine 5'-phosphate decarboxylase
1.8 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase (pyrF) from Campylobacter jejuni subsp. jejuni NCTC 11168
 0.38 15.20 0.86 10-233 X-ray 1.80 homo-dimer HHblits 0.28
8dop.1.A
2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase
Crystal structure of 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase from Klebsiella aerogenes (P1 Form)
 0.38 18.05 0.86 2-227 X-ray 2.00 homo-dimer HHblits 0.28
3ajx.1.A
3-hexulose-6-phosphate synthase
Crystal Structure of 3-Hexulose-6-Phosphate Synthase
 0.43 22.22 0.83 4-227 X-ray 1.60 homo-dimer 2 x MG HHblits 0.30
1dbt.1.A
OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
CRYSTAL STRUCTURE OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE FROM BACILLUS SUBTILIS COMPLEXED WITH UMP
 0.38 18.14 0.86 8-230 X-ray 2.40 homo-dimer 2 x U5P HHblits 0.28
8vdw.1.A
Biotin synthase
X-Ray Crystal Structure of the biotin synthase from V. parvula
 0.42 19.00 0.84 13-224 X-ray 1.81 homo-dimer 2 x Q46, 2 x SAM, 2 x SF4, 2 x DTB HHblits 0.29
3ldv.1.A
Orotidine 5'-phosphate decarboxylase
1.77 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961
 0.37 17.24 0.85 4-227 X-ray 1.77 homo-dimer 1 x MG HHblits 0.28
3uwq.1.A
Orotidine 5'-phosphate decarboxylase
1.80 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961 in complex with uridine-5'-monophosphate (UMP)
 0.37 17.24 0.85 4-227 X-ray 1.80 homo-dimer 2 x U5P, 1 x XPE HHblits 0.28
3tfx.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of Orotidine 5'-phosphate decarboxylase from Lactobacillus acidophilus
 0.38 18.63 0.86 5-228 X-ray 2.19 homo-dimer HHblits 0.27
3tfx.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of Orotidine 5'-phosphate decarboxylase from Lactobacillus acidophilus
 0.39 18.63 0.86 5-228 X-ray 2.19 homo-dimer HHblits 0.27
5tql.1.A
Imidazole glycerol phosphate synthase subunit HisF
Crystal structure of TIM-Barrel protein HisF-C9S
 0.45 16.83 0.85 2-222 X-ray 1.90 monomer HHblits 0.27
4lui.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of Orotidine 5'-monophosphate decarboxylase from methanocaldococcus jannaschii
 0.39 16.00 0.84 8-228 X-ray 1.60 homo-dimer HHblits 0.28
4luj.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of Orotidine 5'-monophosphate decarboxylase from methanocaldococcus jannaschii complexed with inhibitor BMP
 0.39 16.00 0.84 8-228 X-ray 1.60 homo-dimer 2 x BMP HHblits 0.28
4z08.1.A
de novo designed kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 1 KE07 design
 0.45 15.84 0.85 2-222 X-ray 1.80 monomer HHblits 0.27
3vnd.1.A
Tryptophan synthase alpha chain
Crystal structure of tryptophan synthase alpha-subunit from the psychrophile Shewanella frigidimarina K14-2
 0.43 17.68 0.83 3-215 X-ray 2.60 monomer HHblits 0.29
3nav.1.A
Tryptophan synthase alpha chain
Crystal structure of an alpha subunit of tryptophan synthase from Vibrio cholerae O1 biovar El Tor str. N16961
 0.42 16.67 0.83 3-215 X-ray 2.10 homo-dimer HHblits 0.29
3nav.1.B
Tryptophan synthase alpha chain
Crystal structure of an alpha subunit of tryptophan synthase from Vibrio cholerae O1 biovar El Tor str. N16961
 0.42 16.67 0.83 3-215 X-ray 2.10 homo-dimer HHblits 0.29
6nke.1.A
Geranylgeranylglyceryl phosphate synthase
Wild-type GGGPS from Thermoplasma volcanium
 0.36 15.00 0.84 11-234 X-ray 1.72 homo-dimer 4 x IMD HHblits 0.28
1ka9.1.B
imidazole glycerol phosphate synthase
Imidazole Glycerol Phosphate Synthase
 0.46 15.20 0.86 1-223 X-ray 2.30 hetero-1-1-mer HHblits 0.26
1kfc.1.A
TRYPTOPHAN SYNTHASE ALPHA CHAIN
CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM With Indole Propanol Phosphate
 0.42 15.15 0.83 3-215 X-ray 1.50 hetero-2-2-mer 2 x IPL, 2 x PLP HHblits 0.28
5kzm.1.A
Tryptophan synthase alpha chain
Crystal structure of Tryptophan synthase alpha-beta chain complex from Francisella tularensis
 0.41 16.75 0.83 3-214 X-ray 2.80 hetero-2-2-mer 4 x CA HHblits 0.28
1xc4.1.A
Tryptophan synthase alpha chain
Crystal structure of wild-type tryptophan synthase alpha-subunits from Escherichia coli
 0.43 15.66 0.83 3-215 X-ray 2.80 homo-tetramer HHblits 0.28
3o63.1.A
Probable thiamine-phosphate pyrophosphorylase
Crystal Structure of Thiamin Phosphate Synthase from Mycobacterium tuberculosis
 0.42 14.36 0.85 5-229 X-ray 2.35 homo-dimer HHblits 0.26
2j9x.1.A
TRYPTOPHAN SYNTHASE ALPHA CHAIN
TRYPTOPHAN SYNTHASE IN COMPLEX WITH GP, ALPHA-D,L-GLYCEROL-PHOSPHATE, CS, PH6.5 - ALPHA AMINOACRYLATE FORM - (GP)E(A-A)
 0.44 15.15 0.83 3-215 X-ray 1.90 hetero-oligomer 2 x G3P, 2 x P1T, 6 x CS HHblits 0.28
2j9y.1.A
TRYPTOPHAN SYNTHASE ALPHA CHAIN
TRYPTOPHAN SYNTHASE Q114N MUTANT IN COMPLEX WITH COMPOUND II
 0.42 15.15 0.83 3-215 X-ray 1.80 hetero-oligomer 2 x FOO HHblits 0.28
1ttp.1.A
TRYPTOPHAN SYNTHASE
TRYPTOPHAN SYNTHASE (E.C.4.2.1.20) IN THE PRESENCE OF CESIUM, ROOM TEMPERATURE
 0.42 15.15 0.83 3-215 X-ray 2.30 hetero-oligomer 4 x CS, 2 x PLP HHblits 0.28
4hn4.1.C
Tryptophan synthase alpha chain
Tryptophan synthase in complex with alpha aminoacrylate E(A-A) form and the F9 inhibitor in the alpha site
 0.44 15.15 0.83 3-215 X-ray 1.64 hetero-2-2-mer 2 x F9F, 2 x 0JO, 6 x BCN, 4 x CS HHblits 0.28
7k0b.1.A
Tryptophan synthase alpha chain
The internal aldimine form of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with cesium ion at the metal coordination site. A random beta-P270L mutation was inserted during PCR step
 0.43 15.15 0.83 3-215 X-ray 1.57 hetero-1-1-mer 1 x SER, 1 x PLP, 1 x BCN, 2 x CS HHblits 0.28
2wsy.1.C
TRYPTOPHAN SYNTHASE
CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE
 0.42 15.15 0.83 3-215 X-ray 3.05 hetero-2-2-mer 2 x PLP HHblits 0.28
6ouy.1.A
Tryptophan synthase alpha chain
The crystal structure of the isolate tryptophan synthase alpha-chain from Salmonella enterica serovar typhimurium at 1.60 Angstrom resolution
 0.42 15.15 0.83 3-215 X-ray 1.60 monomer HHblits 0.28
6vnt.1.C
Tryptophan synthase alpha chain
Tryptophan synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and sodium ion at the metal coordination site at 1.25 Angstrom resolution
 0.44 15.15 0.83 3-215 X-ray 1.25 hetero-2-2-mer 2 x F9F, 2 x 0JO HHblits 0.28
6x0c.1.A
Tryptophan synthase alpha chain
Tryptophan Synthase mutant beta-Q114A in complex with Cesium ion at the metal coordination site and aminoacrylate and benzimidazole at the enzyme beta site
 0.42 15.15 0.83 3-215 X-ray 1.45 hetero-1-1-mer 3 x BZI, 1 x 0JO, 2 x CS HHblits 0.28
2tys.1.C
TRYPTOPHAN SYNTHASE
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
 0.42 15.15 0.83 3-215 X-ray 1.90 hetero-2-2-mer 2 x PLT HHblits 0.28
2tsy.1.C
TRYPTOPHAN SYNTHASE
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
 0.43 15.15 0.83 3-215 X-ray 2.50 hetero-2-2-mer 2 x G3P, 2 x PLS HHblits 0.28
2trs.1.C
TRYPTOPHAN SYNTHASE
CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
 0.43 15.15 0.83 3-215 X-ray 2.04 hetero-2-2-mer 2 x IPL, 2 x PLS HHblits 0.28
1xcf.1.A
Tryptophan synthase alpha chain
Crystal structure of P28L/Y173F tryptophan synthase alpha-subunits from Escherichia coli
 0.41 15.15 0.83 3-215 X-ray 1.80 homo-tetramer HHblits 0.28
2cz5.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3
 0.40 18.75 0.81 10-229 X-ray 1.85 homo-dimer HHblits 0.30
2cz5.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3
 0.39 18.75 0.81 10-229 X-ray 1.85 homo-dimer HHblits 0.30
2czf.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 complexed with XMP
 0.39 18.75 0.81 10-229 X-ray 1.85 homo-dimer 2 x XMP HHblits 0.30
2czf.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 complexed with XMP
 0.39 18.75 0.81 10-229 X-ray 1.85 homo-dimer 2 x XMP HHblits 0.30
2czd.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 at 1.6 A resolution
 0.39 18.75 0.81 10-229 X-ray 1.60 homo-dimer 1 x DTT HHblits 0.30
2czd.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 at 1.6 A resolution
 0.39 18.75 0.81 10-229 X-ray 1.60 homo-dimer 1 x DTT HHblits 0.30
2cze.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 complexed with UMP
 0.39 18.75 0.81 10-229 X-ray 1.85 homo-dimer 2 x U5P HHblits 0.30
2cze.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-phosphate decarboxylase from Pyrococcus horikoshii OT3 complexed with UMP
 0.39 18.75 0.81 10-229 X-ray 1.85 homo-dimer 2 x U5P HHblits 0.30
3nl2.1.A
Thiamine biosynthetic bifunctional enzyme
The Crystal Structure of Candida glabrata THI6, a Bifunctional Enzyme involved in Thiamin Biosyhthesis of Eukaryotes
 0.38 11.82 0.85 6-231 X-ray 3.08 homo-hexamer HHblits 0.26
1a5a.1.A
TRYPTOPHAN SYNTHASE (ALPHA CHAIN)
CRYO-CRYSTALLOGRAPHY OF A TRUE SUBSTRATE, INDOLE-3-GLYCEROL PHOSPHATE, BOUND TO A MUTANT (ALPHAD60N) TRYPTOPHAN SYNTHASE ALPHA2BETA2 COMPLEX REVEALS THE CORRECT ORIENTATION OF ACTIVE SITE ALPHA GLU 49
 0.43 14.65 0.83 3-215 X-ray 1.90 hetero-2-2-mer 2 x K, 2 x PLP HHblits 0.28
1v7y.3.A
Tryptophan synthase alpha chain
Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli at room temperature
 0.42 14.65 0.83 3-215 X-ray 2.50 homo-dimer HHblits 0.28
1v7y.2.A
Tryptophan synthase alpha chain
Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli at room temperature
 0.42 14.65 0.83 3-215 X-ray 2.50 monomer HHblits 0.28
1wq5.3.B
Tryptophan synthase alpha chain
Crystal structure of tryptophan synthase alpha-subunit from Escherichia coli
 0.42 14.65 0.83 3-215 X-ray 2.30 homo-tetramer HHblits 0.28
1kfk.1.A
TRYPTOPHAN SYNTHASE ALPHA CHAIN
Crystal structure of Tryptophan Synthase From Salmonella Typhimurium
 0.42 15.74 0.83 4-215 X-ray 2.40 hetero-oligomer 2 x PLP HHblits 0.28
3iio.1.A
KE07
Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series
 0.44 14.85 0.85 3-223 X-ray 2.25 monomer HHblits 0.26
3pr2.1.A
Tryptophan synthase alpha chain
Tryptophan synthase indoline quinonoid structure with F9 inhibitor in alpha site
 0.43 15.74 0.83 4-215 X-ray 1.85 hetero-2-2-mer 2 x F9F, 2 x 7MN, 6 x CS HHblits 0.28
6c7h.1.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 18 Design Trp50Ala mutant
 0.44 15.50 0.84 2-220 X-ray 2.43 monomer HHblits 0.27
2j9z.1.A
TRYPTOPHAN SYNTHASE ALPHA CHAIN
TRYPTOPHAN SYNTHASE T110 MUTANT COMPLEX
 0.42 15.74 0.83 4-215 X-ray 1.80 hetero-oligomer 2 x PLP HHblits 0.28
2vep.1.A
PHOSPHORIBOSYL ISOMERASE A
Crystal Structure Of The Full Length Bifunctional Enzyme Pria
 0.42 15.82 0.82 1-216 X-ray 1.80 monomer HHblits 0.29
1vzw.1.A
PHOSPHORIBOSYL ISOMERASE A
Crystal structure of the bifunctional protein Pria
 0.42 15.82 0.82 1-216 X-ray 1.80 monomer HHblits 0.29
2x30.1.A
PHOSPHORIBOSYL ISOMERASE A
Crystal structure of the r139n mutant of a bifunctional enzyme pria
 0.42 15.82 0.82 1-216 X-ray 1.95 monomer HHblits 0.29
5dn1.1.A
Phosphoribosyl isomerase A
Crystal structure of Phosphoribosyl isomerase A from Streptomyces coelicolor
 0.42 15.82 0.82 1-216 X-ray 1.95 monomer 1 x AMZ HHblits 0.29
2wjz.1.A
IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISF
Crystal structure of (HisH) K181A Y138A mutant of imidazoleglycerolphosphate synthase (HisH HisF) which displays constitutive glutaminase activity
 0.44 16.58 0.84 1-218 X-ray 2.60 hetero-1-1-mer HHblits 0.27
3zr4.2.A
IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF
STRUCTURAL EVIDENCE FOR AMMONIA TUNNELING ACROSS THE (BETA-ALPHA)8 BARREL OF THE IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE BIENZYME COMPLEX
 0.45 16.58 0.84 1-218 X-ray 2.41 hetero-1-1-mer 1 x GLN HHblits 0.27
3zr4.3.A
IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF
STRUCTURAL EVIDENCE FOR AMMONIA TUNNELING ACROSS THE (BETA-ALPHA)8 BARREL OF THE IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE BIENZYME COMPLEX
 0.44 16.58 0.84 1-218 X-ray 2.41 hetero-1-1-mer HHblits 0.27
6ymu.1.A
Imidazole glycerol phosphate synthase subunit HisF
Imidazole Glycerol Phosphate Synthase
 0.45 16.58 0.84 1-218 X-ray 2.11 monomer HHblits 0.27
6ymu.3.A
Imidazole glycerol phosphate synthase subunit HisF
Imidazole Glycerol Phosphate Synthase
 0.45 16.58 0.84 1-218 X-ray 2.11 monomer HHblits 0.27
6rtz.1.A
Imidazole glycerol phosphate synthase subunit HisF
Light-Regulation of Imidazole Glycerol Phosphate Synthase by Interference with its Allosteric Machinery through Photo-Sensitive Unnatural Amino Acids
 0.44 16.58 0.84 1-218 X-ray 2.87 hetero-1-1-mer HHblits 0.27
7ac8.3.A
Imidazole glycerol phosphate synthase subunit HisF
Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
 0.44 16.58 0.84 1-218 X-ray 2.06 hetero-1-1-mer 1 x GUO, 1 x GLN HHblits 0.27
1gpw.1.A
HISF PROTEIN
Structural evidence for ammonia tunneling across the (beta/alpha)8 barrel of the imidazole glycerol phosphate synthase bienzyme complex.
 0.44 17.09 0.84 1-218 X-ray 2.40 hetero-1-1-mer HHblits 0.27
1gpw.3.A
HISF PROTEIN
Structural evidence for ammonia tunneling across the (beta/alpha)8 barrel of the imidazole glycerol phosphate synthase bienzyme complex.
 0.44 17.09 0.84 1-218 X-ray 2.40 hetero-1-1-mer HHblits 0.27
1tjr.1.A
BX1
Crystal structure of wild-type BX1 complexed with a sulfate ion
 0.43 13.71 0.83 3-215 X-ray 2.30 monomer HHblits 0.28
8b03.1.A
Tryptophan synthase alpha chain
TRYPTOPHAN SYNTHASE - Cryo-trapping by the spitrobot crystal plunger after 0 sec
 0.42 15.23 0.83 4-215 X-ray 2.22 hetero-2-2-mer 2 x PLP, 2 x CS HHblits 0.28
8b08.1.A
Tryptophan synthase alpha chain
TRYPTOPHAN SYNTHASE - Cryo-trapping by the spitrobot crystal plunger after 30 sec
 0.43 15.23 0.83 4-215 X-ray 2.50 hetero-1-1-mer 1 x G3P, 1 x CS, 1 x PLS HHblits 0.28
4evz.1.A
HisF-LUCA
Structure of HisF-LUCA
 0.44 13.43 0.84 1-220 X-ray 1.46 monomer 2 x PI HHblits 0.26
4u28.1.A
Phosphoribosyl isomerase A
Crystal structure of apo Phosphoribosyl isomerase A from Streptomyces sviceus ATCC 29083
 0.43 14.80 0.82 1-216 X-ray 1.33 monomer HHblits 0.28
2rkx.1.A
Cyclase subunit of imidazoleglycerol_evolvedcerolphosphate synthase
The 3D structure of chain D, cyclase subunit of imidazoleglycerol_evolvedcerolphosphate synthase
 0.44 16.08 0.84 1-218 X-ray 2.25 monomer HHblits 0.27
7qc7.1.A
Imidazole glycerol phosphate synthase subunit HisF
HisF-C9A-D11E-V33A_L50H_I52H mutant (apo) from T. maritima
 0.44 16.67 0.83 2-218 X-ray 1.60 monomer 1 x MES HHblits 0.27
4axk.1.A
1-(5-PHOSPHORIBOSYL)-5-((5'-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO)IMIDAZOLE-4-CARBOXAMIDE ISOMERASE
CRYSTAL STRUCTURE OF subHisA from the thermophile Corynebacterium efficiens
 0.43 16.84 0.82 2-217 X-ray 2.25 monomer HHblits 0.28
4axk.2.A
1-(5-PHOSPHORIBOSYL)-5-((5'-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO)IMIDAZOLE-4-CARBOXAMIDE ISOMERASE
CRYSTAL STRUCTURE OF subHisA from the thermophile Corynebacterium efficiens
 0.43 16.84 0.82 2-217 X-ray 2.25 monomer HHblits 0.28
2ekc.1.A
Tryptophan synthase alpha chain
Structural study of Project ID aq_1548 from Aquifex aeolicus VF5
 0.41 17.26 0.83 3-215 X-ray 2.00 monomer HHblits 0.28
2ekc.2.A
Tryptophan synthase alpha chain
Structural study of Project ID aq_1548 from Aquifex aeolicus VF5
 0.41 17.26 0.83 3-215 X-ray 2.00 monomer HHblits 0.28
1thf.1.A
HISF PROTEIN
CYCLASE SUBUNIT OF IMIDAZOLEGLYCEROLPHOSPHATE SYNTHASE FROM THERMOTOGA MARITIMA
 0.44 17.26 0.83 1-216 X-ray 1.45 homo-dimer HHblits 0.28
6ru0.1.A
Imidazole glycerol phosphate synthase subunit HisF
Light-Regulation of Imidazole Glycerol Phosphate Synthase by Interference with its Allosteric Machinery through Photo-Sensitive Unnatural Amino Acids
 0.44 16.67 0.83 1-217 X-ray 2.65 hetero-1-1-mer HHblits 0.27
6ru0.3.A
Imidazole glycerol phosphate synthase subunit HisF
Light-Regulation of Imidazole Glycerol Phosphate Synthase by Interference with its Allosteric Machinery through Photo-Sensitive Unnatural Amino Acids
 0.44 16.67 0.83 1-217 X-ray 2.65 hetero-1-1-mer HHblits 0.27
5sc8.1.A
Pyruvate kinase
Structure of liver pyruvate kinase in complex with anthraquinone derivative 17
 0.42 11.82 0.85 21-232 X-ray 1.77 homo-tetramer 4 x FBP, 4 x OXL, 2 x E6K, 4 x MG, 4 x K HHblits 0.25
7qc3.1.A
Imidazole glycerol phosphate synthase subunit HisF
HisF from T. maritima
 0.44 16.67 0.83 2-218 X-ray 1.65 monomer HHblits 0.27
4tx9.1.A
Phosphoribosyl isomerase A
Crystal structure of HisAp from Streptomyces sviceus with degraded ProFAR
 0.42 14.87 0.82 1-215 X-ray 1.60 monomer 1 x AMZ HHblits 0.28
4ewn.1.A
Imidazole glycerol phosphate synthase subunit HisF
Structure of HisF-D130V+D176V with bound rCdRP
 0.45 16.67 0.83 1-217 X-ray 1.90 monomer 1 x 0VR HHblits 0.27
3nm1.1.A
Thiamine biosynthetic bifunctional enzyme
The Crystal Structure of Candida glabrata THI6, a Bifunctional Enzyme involved in Thiamin Biosyhthesis of Eukaryotes
 0.37 11.39 0.85 7-231 X-ray 3.21 homo-hexamer 6 x 3NM, 6 x IFP, 6 x POP, 6 x MG HHblits 0.25
1h5y.1.A
HISF
HisF protein from Pyrobaculum aerophilum
 0.45 16.08 0.84 1-218 X-ray 2.00 monomer HHblits 0.27
4x2r.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Crystal structure of PriA from Actinomyces urogenitalis
 0.42 17.10 0.81 3-215 X-ray 1.05 monomer 1 x CXS HHblits 0.29
6vdg.1.A
Imidazole glycerol phosphate synthase subunit HisF
Crystal Structure of the Y182A HisF Mutant from Thermotoga maritima
 0.44 17.26 0.83 1-216 X-ray 2.79 monomer HHblits 0.27
1rd5.1.A
Tryptophan synthase alpha chain, chloroplast
Crystal structure of Tryptophan synthase alpha chain homolog BX1: a member of the chemical plant defense system
 0.43 13.27 0.82 4-215 X-ray 2.02 monomer 1 x MLA HHblits 0.28
1rd5.2.A
Tryptophan synthase alpha chain, chloroplast
Crystal structure of Tryptophan synthase alpha chain homolog BX1: a member of the chemical plant defense system
 0.42 13.27 0.82 4-215 X-ray 2.02 monomer 1 x MLA HHblits 0.28
3ve7.1.B
Orotidine-5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Metallosphaera sedula complexed with inhibitor BMP
 0.35 16.24 0.83 10-234 X-ray 1.54 homo-dimer 2 x BMP HHblits 0.27
3ve9.1.B
Orotidine-5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Metallosphaera sedula
 0.36 16.24 0.83 10-234 X-ray 1.45 homo-dimer HHblits 0.27
3ve9.1.A
Orotidine-5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Metallosphaera sedula
 0.35 16.24 0.83 10-234 X-ray 1.45 homo-dimer HHblits 0.27
1vh7.1.A
Imidazole glycerol phosphate synthase subunit hisF
Crystal structure of a cyclase subunit of imidazolglycerolphosphate synthase
 0.43 16.75 0.83 2-217 X-ray 1.90 monomer HHblits 0.27
4w9t.1.A
Phosphoribosyl isomerase A
Crystal structure of HisAP from Streptomyces sp. Mg1
 0.42 14.87 0.82 1-215 X-ray 1.57 monomer HHblits 0.28
5d32.1.A
De novo kemp eliminase KE07 round 6
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 11 round 6
 0.43 15.66 0.83 1-217 X-ray 2.10 homo-dimer HHblits 0.27
5kp9.1.A
EPN-01*
Structure of Nanoparticle Released from Enveloped Protein Nanoparticle
 0.46 14.29 0.82 3-233 EM 0.00 homo-60-mer HHblits 0.27
7qc9.1.A
Imidazole glycerol phosphate synthase subunit HisF
HisF-C9A-D11E-V33A_L50H_I52H mutant in complex with Ni(II) from T. maritima
 0.44 15.74 0.83 2-217 X-ray 1.80 monomer 1 x NI HHblits 0.27
4wd0.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Crystal structure of HisAp form Arthrobacter aurescens
 0.41 15.38 0.82 2-216 X-ray 1.50 homo-hexamer HHblits 0.28
4n2y.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Archaeoglobus fulgidus
 0.39 14.21 0.83 10-227 X-ray 1.55 homo-dimer HHblits 0.27
4muz.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Archaeoglobus fulgidus complexed with inhibitor BMP
 0.40 14.21 0.83 10-227 X-ray 1.39 homo-dimer 2 x BMP HHblits 0.27
4n2y.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Archaeoglobus fulgidus
 0.40 14.21 0.83 10-227 X-ray 1.55 homo-dimer HHblits 0.27
5d38.1.B
De novo kemp eliminase KE07 round 7-2
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 17 round 7-2
 0.44 15.74 0.83 3-218 X-ray 1.43 homo-dimer HHblits 0.27
5d38.1.A
De novo kemp eliminase KE07 round 7-2
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 17 round 7-2
 0.44 15.74 0.83 3-218 X-ray 1.43 homo-dimer HHblits 0.27
6ct3.1.A
Kemp eliminase
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 27 round 7-2
 0.44 15.74 0.83 3-218 X-ray 1.90 monomer 1 x 6VP HHblits 0.27
8szz.1.E
O32-ZL4 Component B
CryoEM Structure of Computationally Designed Nanocage O32-ZL4
 0.44 14.36 0.82 3-232 EM 0.00 hetero-24-24-mer HHblits 0.28
2iss.1.A
Pyridoxal biosynthesis lyase pdxS
Structure of the PLP synthase Holoenzyme from Thermotoga maritima
 0.39 14.21 0.83 20-235 X-ray 2.90 hetero-12-12-mer 12 x 5RP HHblits 0.27
5n2p.1.A
Tryptophan synthase alpha chain
Sulfolobus solfataricus Tryptophan Synthase A
 0.41 16.58 0.81 6-215 X-ray 2.06 monomer HHblits 0.28
6hul.1.A
Tryptophan synthase alpha chain
Sulfolobus solfataricus Tryptophan Synthase AB Complex
 0.43 16.58 0.81 6-215 X-ray 2.55 hetero-1-1-mer 1 x G3P, 1 x SER, 1 x PLP HHblits 0.28
5d2y.1.A
De novo designed kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 7 Round 5
 0.44 15.23 0.83 3-218 X-ray 1.98 monomer HHblits 0.27
2v81.1.A
2-DEHYDRO-3-DEOXY-6-PHOSPHOGALACTONATE ALDOLASE
Native KDPGal structure
 0.43 13.92 0.82 1-233 X-ray 2.40 homo-trimer HHblits 0.28
6c7v.1.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 22 round 5
 0.44 15.82 0.82 3-217 X-ray 1.64 monomer HHblits 0.27
3o16.1.A
Thiamine-phosphate pyrophosphorylase
Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase K159A
 0.41 14.29 0.82 14-232 X-ray 2.10 monomer HHblits 0.27
8a8n.1.A
EPN-pX
Structure of self-assembling engineered protein nanocage (EPN) fused with hepatitis A pX protein
 0.46 13.92 0.82 4-232 EM 0.00 monomer HHblits 0.27
3iip.1.A
KE7 R6 3/7F
Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series
 0.43 15.31 0.82 3-217 X-ray 2.30 monomer HHblits 0.27
1g69.1.A
THIAMIN PHOSPHATE SYNTHASE
THIAMIN PHOSPHATE SYNTHASE
 0.41 14.29 0.82 14-232 X-ray 1.50 monomer 1 x MG, 1 x ICP, 1 x POP, 1 x TZP HHblits 0.27
1g4t.2.A
THIAMIN PHOSPHATE SYNTHASE
THIAMIN PHOSPHATE SYNTHASE
 0.41 13.78 0.82 14-232 X-ray 1.55 monomer 1 x MG, 1 x FTP, 1 x POP HHblits 0.26
3o15.1.A
Thiamine-phosphate pyrophosphorylase
Crystal Structure of Bacillus subtilis Thiamin Phosphate Synthase Complexed with a Carboxylated Thiazole Phosphate
 0.41 13.78 0.82 14-232 X-ray 1.95 monomer 1 x 3NM, 1 x IFP, 1 x POP HHblits 0.26
8ed3.1.A
Designed I3-01 icosahedron
Structure of a nanoparticle with icosahedral symmetry
 0.45 15.10 0.81 3-229 EM 0.00 homo-60-mer HHblits 0.28
5ac8.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA with mutations D10G, dup13-15, G102A
 0.41 17.19 0.81 13-225 X-ray 1.70 monomer HHblits 0.28
1g4e.1.A
THIAMIN PHOSPHATE SYNTHASE
THIAMIN PHOSPHATE SYNTHASE
 0.40 13.85 0.82 15-232 X-ray 1.60 monomer HHblits 0.27
8jga.1.A
'Peptidyl-prolyl cis-trans isomerase FKBP1A,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase'
Cryo-EM structure of Mi3 fused with FKBP
 0.44 13.99 0.81 4-231 EM 0.00 monomer HHblits 0.27
7b3y.1.A
'Fibronectin binding protein,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase'
Structure of a nanoparticle for a COVID-19 vaccine candidate
 0.43 13.92 0.82 3-232 EM 0.00 homo-60-mer HHblits 0.27
1g4p.1.A
THIAMIN PHOSPHATE SYNTHASE
THIAMIN PHOSPHATE SYNTHASE
 0.41 13.85 0.82 15-232 X-ray 2.50 monomer 1 x MG, 1 x FQP HHblits 0.26
1g4s.2.A
THIAMIN PHOSPHATE SYNTHASE
THIAMIN PHOSPHATE SYNTHASE
 0.41 13.85 0.82 15-232 X-ray 1.70 monomer 1 x MG, 1 x TPS, 1 x POP HHblits 0.26
8far.1.B
I432-1-CC
Accurate computational design of genetically encoded 3D protein crystals
 0.43 13.54 0.81 2-231 X-ray 3.66 hetero-1-1-mer HHblits 0.28
7nhe.1.A
Pyridoxal 5'-phosphate synthase subunit PDX1.3
Crystal structure of Arabidopsis thaliana Pdx1K166R-I333 complex
 0.38 12.18 0.83 19-235 X-ray 2.23 homo-12-mer 12 x KPR HHblits 0.26
1vlw.1.A
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
Crystal structure of 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (TM0066) from Thermotoga maritima at 2.30 A resolution
 0.43 14.58 0.81 3-230 X-ray 2.30 monomer HHblits 0.28
1eua.1.B
KDPG ALDOLASE
SCHIFF BASE INTERMEDIATE IN KDPG ALDOLASE FROM ESCHERICHIA COLI
 0.42 12.44 0.81 4-231 X-ray 1.95 homo-trimer 3 x PYR HHblits 0.27
1eua.1.C
KDPG ALDOLASE
SCHIFF BASE INTERMEDIATE IN KDPG ALDOLASE FROM ESCHERICHIA COLI
 0.42 12.44 0.81 4-231 X-ray 1.95 homo-trimer 3 x PYR HHblits 0.27
1fq0.1.B
KDPG ALDOLASE
KDPG ALDOLASE FROM ESCHERICHIA COLI
 0.41 12.44 0.81 4-231 X-ray 2.10 homo-trimer HHblits 0.27
4ads.1.A
PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE
Crystal structure of plasmodial PLP synthase complex
 0.38 12.76 0.82 20-235 X-ray 3.61 hetero-12-12-mer HHblits 0.26
1g67.1.A
THIAMIN PHOSPHATE SYNTHASE
THIAMIN PHOSPHATE SYNTHASE
 0.41 13.92 0.82 15-231 X-ray 1.40 monomer 1 x MG, 1 x ICP, 1 x POP, 1 x TZP HHblits 0.27
5ac6.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S.enterica HisA mutant D10G, dup13-15, Q24L, G102A
 0.41 16.75 0.80 13-224 X-ray 1.99 monomer HHblits 0.28
8cwz.1.B
I432-1-X3 Chain B
Accurate computational design of genetically encoded 3D protein crystals
 0.43 12.50 0.81 3-229 X-ray 5.53 hetero-1-1-mer HHblits 0.27
8e01.1.A
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
Structure of engineered nano-cage fusion protein
 0.43 14.06 0.81 3-230 EM 0.00 homo-60-mer HHblits 0.27
5tch.1.A
Tryptophan synthase alpha chain
Crystal structure of tryptophan synthase from M. tuberculosis - ligand-free form, TrpA-G66V mutant
 0.41 13.54 0.81 5-214 X-ray 2.35 hetero-2-2-mer HHblits 0.27
1fwr.1.A
KDPG ALDOLASE
CRYSTAL STRUCTURE OF KDPG ALDOLASE DOUBLE MUTANT K133Q/T161K
 0.40 11.40 0.81 4-231 X-ray 2.70 homo-trimer HHblits 0.27
1wau.1.A
KHG/KDPG ALDOLASE
Structure of KDPG Aldolase E45N mutant
 0.40 11.40 0.81 4-231 X-ray 2.80 homo-trimer HHblits 0.27
2c0a.1.A
KHG/KDPG ALDOLASE
Mechanism of the Class I KDPG aldolase
 0.42 11.40 0.81 4-231 X-ray 1.55 homo-trimer HHblits 0.27
4adt.1.A
PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE
Crystal structure of plasmodial PLP synthase
 0.40 12.82 0.82 20-235 X-ray 2.42 homo-12-mer HHblits 0.26
4adu.1.A
PYRIDOXINE BIOSYNTHETIC ENZYME PDX1 HOMOLOGUE, PUTATIVE
Crystal structure of plasmodial PLP synthase with bound R5P intermediate
 0.40 12.82 0.82 20-235 X-ray 2.44 homo-12-mer 12 x R5P HHblits 0.26
6v82.1.A
Tryptophan synthase alpha chain
Crystal structure of tryptophan synthase from Chlamydia trachomatis D/UW-3/CX
 0.43 11.22 0.82 4-215 X-ray 2.42 hetero-2-2-mer 4 x GLC-FRU HHblits 0.25
1xi3.1.A
Thiamine phosphate pyrophosphorylase
Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001
 0.40 14.21 0.80 14-230 X-ray 1.70 homo-dimer 1 x NI HHblits 0.28
1wa3.1.A
2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE
Mechanism of the Class I KDPG aldolase
 0.43 13.61 0.80 4-230 X-ray 1.90 homo-trimer 3 x PYR HHblits 0.27
4ijb.1.A
Engineered Protein OR288
Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR288
 0.44 15.34 0.79 6-221 X-ray 1.74 monomer HHblits 0.28
8cus.1.B
I432-1(NaCl) Chain B
Accurate computational design of genetically encoded 3D protein crystals
 0.40 15.51 0.79 3-229 X-ray 3.98 hetero-1-1-mer HHblits 0.29
3vcr.1.A
putative Kdpg (2-keto-3-deoxy-6-phosphogluconate) aldolase
Crystal structure of a putative Kdpg (2-keto-3-deoxy-6-phosphogluconate) aldolase from Oleispira antarctica
 0.38 13.23 0.79 4-229 X-ray 1.84 homo-trimer 3 x PYR HHblits 0.28
7a20.1.A
Tryptophan synthase alpha chain,Tryptophan synthase beta chain
Azobenzene-Based Inhibitors for Tryptophan Synthase
 0.42 15.34 0.79 14-215 X-ray 2.50 homo-tetramer 2 x 144 HHblits 0.28
2yw4.1.A
4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase
Crystal Structure Analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase from TTHB1
 0.41 17.55 0.79 4-229 X-ray 2.53 homo-trimer HHblits 0.28
1vhc.1.A
Putative KHG/KDPG aldolase
Crystal structure of a putative KHG/KDPG aldolase
 0.42 14.06 0.81 4-230 X-ray 1.89 homo-trimer HHblits 0.26
3tc6.1.A
Indole-3-glycerol phosphate synthase
Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR63.
 0.44 14.29 0.79 7-221 X-ray 1.60 monomer HHblits 0.28
6xh5.1.A
helical fusion design
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
 0.44 14.29 0.79 5-228 X-ray 3.32 homo-trimer HHblits 0.28
6xh5.1.B
helical fusion design
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
 0.44 14.29 0.79 5-228 X-ray 3.32 homo-trimer HHblits 0.28
6xh5.1.C
helical fusion design
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
 0.45 14.29 0.79 5-228 X-ray 3.32 homo-trimer HHblits 0.28
6xh5.2.A
helical fusion design
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
 0.45 14.29 0.79 5-228 X-ray 3.32 homo-trimer HHblits 0.28
6xh5.2.B
helical fusion design
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
 0.43 14.29 0.79 5-228 X-ray 3.32 homo-trimer HHblits 0.28
6xh5.2.C
helical fusion design
Hierarchical design of multi-scale protein complexes by combinatorial assembly of oligomeric helical bundle and repeat protein building blocks
 0.44 14.29 0.79 5-228 X-ray 3.32 homo-trimer HHblits 0.28
5ahf.1.A
?
Crystal structure of Salmonella enterica HisA D7N with ProFAR
 0.42 17.11 0.79 21-225 X-ray 2.20 monomer 1 x GUO HHblits 0.28
5lnt.1.A
Pyridoxal 5'-phosphate synthase subunit PDX1.1
Crystal structure of Arabidopsis thaliana Pdx1K166R-preI320 complex
 0.36 11.79 0.82 20-234 X-ray 2.32 homo-12-mer 12 x KPR HHblits 0.25
3t55.1.A
Indole-3-glycerol phosphate synthase
Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with Phenoxymethyl Benzoic Acid (PMBA)
 0.46 14.21 0.80 17-231 X-ray 2.06 monomer 1 x 4RG HHblits 0.27
3t40.1.A
Indole-3-glycerol phosphate synthase
Crystal Structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) complex with N-2-Carboxyphenyl Glycine (CPG)
 0.46 14.21 0.80 17-231 X-ray 1.75 monomer 1 x 3RG HHblits 0.27
3qja.1.A
Indole-3-glycerol phosphate synthase
Crystal Structure of the Mycobacterium tuberculosis Indole-3-glycerol phosphate synthase (TrpC) in apo form
 0.47 14.21 0.80 17-231 X-ray 1.29 monomer HHblits 0.27
5g2w.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA mutant D10G, G102A
 0.42 16.58 0.79 21-225 X-ray 2.10 monomer HHblits 0.28
4fb7.1.A
Indole-3-glycerol phosphate synthase
The apo form of idole-3-glycerol phosphate synthase (TrpC) form Mycobacterium tuberculosis
 0.45 14.21 0.80 17-231 X-ray 1.30 monomer 1 x BTB HHblits 0.27
4df1.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus complexed with inhibitor BMP
 0.33 14.66 0.80 4-229 X-ray 1.90 homo-dimer 2 x BMP, 2 x NI HHblits 0.26
4df0.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus
 0.32 14.66 0.80 4-229 X-ray 1.50 homo-dimer 2 x NI HHblits 0.26
4df0.1.B
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Thermoproteus neutrophilus
 0.33 14.66 0.80 4-229 X-ray 1.50 homo-dimer 2 x NI HHblits 0.26
8di1.1.A
KDPG and KHG aldolase
Bfo2294: Tannerella forsythia 2-Keto-3-deoxy-6-phosphogluconate aldolase (KDPG) and 4-Hydroxy-2-oxoglutarate aldolase (KHG)
 0.43 14.29 0.79 4-228 X-ray 2.20 monomer HHblits 0.27
5ahe.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Crystal structure of Salmonella enterica HisA
 0.41 17.20 0.78 21-224 X-ray 1.70 monomer HHblits 0.28
3fem.1.A
Pyridoxine biosynthesis protein SNZ1
Structure of the synthase subunit Pdx1.1 (Snz1) of PLP synthase from Saccharomyces cerevisiae
 0.35 12.11 0.80 21-233 X-ray 3.02 homo-hexamer HHblits 0.27
3ceu.1.A
Thiamine phosphate pyrophosphorylase
Crystal structure of thiamine phosphate pyrophosphorylase (BT_0647) from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR268
 0.33 9.90 0.81 4-232 X-ray 2.30 monomer HHblits 0.26
3ceu.2.A
Thiamine phosphate pyrophosphorylase
Crystal structure of thiamine phosphate pyrophosphorylase (BT_0647) from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium target BtR268
 0.32 9.90 0.81 4-232 X-ray 2.30 monomer HHblits 0.26
5g5i.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA mutant D10G
 0.41 16.67 0.78 21-224 X-ray 2.00 monomer HHblits 0.28
1hg3.1.A
TRIOSEPHOSPHATE ISOMERASE
Crystal structure of tetrameric TIM from Pyrococcus woesei.
 0.34 15.59 0.78 7-226 X-ray 2.70 homo-tetramer 4 x 3PP HHblits 0.28
5a5w.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Crystal structure of Salmonella enterica HisA D7N D176A with ProFAR
 0.41 17.30 0.78 21-223 X-ray 1.60 monomer 1 x GUO HHblits 0.28
5ab3.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S.enterica HisA mutant D7N, D10G, dup13-15, Q24L, G102A
 0.42 17.30 0.78 21-223 X-ray 1.80 monomer 1 x 2ER HHblits 0.28
5g1t.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA mutant dup13-15, D10G
 0.41 16.76 0.78 22-224 X-ray 1.70 monomer HHblits 0.28
8s2w.1.A
Pyridoxal 5'-phosphate synthase subunit PDX1.3
SSX structure of Arabidopsis thaliana Pdx1.3 grown in seeded batch conditions
 0.36 11.46 0.81 19-236 X-ray 2.50 homo-12-mer HHblits 0.25
5ac7.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA with mutations D7N, D10G, dup13-15
 0.41 16.76 0.78 22-224 X-ray 1.90 monomer HHblits 0.28
5g4w.1.A
HISA
S. enterica HisA mutant D7N, D10G, Dup13-15 (VVR) with substrate ProFAR
 0.41 16.76 0.78 22-224 X-ray 2.30 monomer 1 x GUO HHblits 0.28
5l6u.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. ENTERICA HISA MUTANT - D10G, DUP13-15, Q24L, G102A
 0.41 16.76 0.78 21-223 X-ray 1.60 monomer HHblits 0.28
2e09.1.A
Tryptophan synthase alpha chain
Structure of mutant tryptophan synthase alpha-subunit (E74A) from a hyperthermophile, Pyrococcus furiosus
 0.40 15.05 0.78 14-216 X-ray 2.40 monomer HHblits 0.28
4e38.1.A
Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase
Crystal structure of probable keto-hydroxyglutarate-aldolase from Vibrionales bacterium SWAT-3 (Target EFI-502156)
 0.42 13.16 0.80 4-230 X-ray 1.64 homo-trimer HHblits 0.26
4e38.1.C
Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase
Crystal structure of probable keto-hydroxyglutarate-aldolase from Vibrionales bacterium SWAT-3 (Target EFI-502156)
 0.42 13.16 0.80 4-230 X-ray 1.64 homo-trimer HHblits 0.26
5kmy.1.A
Tryptophan synthase alpha chain
Crystal structure of tryptophan synthase subunit alpha from Legionella pneumophila str. Paris
 0.36 15.22 0.77 14-213 X-ray 1.91 monomer HHblits 0.28
6hxg.1.C
Pyridoxal 5'-phosphate synthase subunit PDX1.3
PDX1.2/PDX1.3 complex (intermediate)
 0.36 11.52 0.80 20-236 X-ray 1.90 hetero-12-12-mer HHblits 0.25
5l9f.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA mutant - D10G, G11D, dup13-15, G44E, G102A
 0.41 16.85 0.77 22-223 X-ray 2.59 monomer HHblits 0.28
5k9x.1.A
Tryptophan synthase alpha chain
Crystal structure of Tryptophan synthase alpha chain from Legionella pneumophila subsp. pneumophila
 0.37 14.67 0.77 14-213 X-ray 2.02 monomer HHblits 0.28
2dzt.1.A
Tryptophan synthase alpha chain
Structure of mutant tryptophan synthase alpha-subunit (D110A) from a hyperthermophile, Pyrococcus furiosus
 0.42 13.90 0.79 14-215 X-ray 2.40 monomer HHblits 0.27
2dzv.1.A
Tryptophan synthase alpha chain
Structure of mutant tryptophan synthase alpha-subunit (D146A) from a hyperthermophile, Pyrococcus furiosus
 0.40 15.14 0.78 14-215 X-ray 2.40 monomer HHblits 0.28
5g1y.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA mutant D10G, dup13-15,V14:2M, Q24L, G102
 0.40 16.85 0.77 22-223 X-ray 1.80 monomer HHblits 0.28
2dzx.1.A
Tryptophan synthase alpha chain
Structure of mutant tryptophan synthase alpha-subunit (E131-132A) from a hyperthermophile, Pyrococcus furiosus
 0.40 15.14 0.78 14-215 X-ray 2.40 monomer HHblits 0.28
1vs1.1.A
3-deoxy-7-phosphoheptulonate synthase
Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP
 0.35 19.02 0.77 13-212 X-ray 2.30 homo-tetramer 4 x MN HHblits 0.28
1vs1.1.D
3-deoxy-7-phosphoheptulonate synthase
Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP
 0.35 19.02 0.77 13-212 X-ray 2.30 homo-tetramer 4 x MN HHblits 0.28
6y88.1.A
Indole-3-glycerol phosphate synthase
IGPS (Indole-3-glycerol phosphate synthase) from Pseudomonas aeruginosa in complex with substrate inhibitor rCdRP
 0.42 12.77 0.79 18-231 X-ray 2.10 monomer 1 x 137 HHblits 0.26
6y88.2.A
Indole-3-glycerol phosphate synthase
IGPS (Indole-3-glycerol phosphate synthase) from Pseudomonas aeruginosa in complex with substrate inhibitor rCdRP
 0.41 12.77 0.79 18-231 X-ray 2.10 monomer 1 x 137 HHblits 0.26
2dzu.1.A
Tryptophan synthase alpha chain
Structure of mutant tryptophan synthase alpha-subunit (D110N) from a hyperthermophile, Pyrococcus furiosus
 0.40 14.59 0.78 14-215 X-ray 2.46 monomer HHblits 0.27
4mm1.1.A
Geranylgeranylglyceryl phosphate synthase
GGGPS from Methanothermobacter thermautotrophicus
 0.32 21.23 0.75 19-228 X-ray 2.80 homo-hexamer 6 x 1GP HHblits 0.30
4mm1.1.E
Geranylgeranylglyceryl phosphate synthase
GGGPS from Methanothermobacter thermautotrophicus
 0.31 21.23 0.75 19-228 X-ray 2.80 homo-hexamer 6 x 1GP HHblits 0.30
4mm1.1.F
Geranylgeranylglyceryl phosphate synthase
GGGPS from Methanothermobacter thermautotrophicus
 0.30 21.23 0.75 19-228 X-ray 2.80 homo-hexamer 6 x 1GP HHblits 0.30
6hx3.1.C
Pyridoxal 5'-phosphate synthase subunit PDX1.3
PDX1.2/PDX1.3 complex
 0.36 11.05 0.80 20-235 X-ray 2.00 hetero-12-12-mer HHblits 0.25
5g2i.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA mutant Dup13-15(VVR)
 0.40 16.85 0.77 13-217 X-ray 1.60 monomer HHblits 0.28
5g4e.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA mutant D10G, Dup13-15, Q24L, G102A, V106L
 0.40 16.94 0.77 23-223 X-ray 2.65 monomer HHblits 0.28
5g4e.2.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA mutant D10G, Dup13-15, Q24L, G102A, V106L
 0.40 16.94 0.77 23-223 X-ray 2.65 monomer HHblits 0.28
3tdn.1.A
FLR SYMMETRIC ALPHA-BETA TIM BARREL
Computationally designed two-fold symmetric Tim-barrel protein, FLR
 0.20 17.30 0.78 17-220 X-ray 1.40 homo-dimer HHblits 0.27
6y88.7.A
Indole-3-glycerol phosphate synthase,Indole-3-glycerol phosphate synthase
IGPS (Indole-3-glycerol phosphate synthase) from Pseudomonas aeruginosa in complex with substrate inhibitor rCdRP
 0.40 12.83 0.79 18-230 X-ray 2.10 monomer HHblits 0.26
3tsm.1.A
Indole-3-glycerol phosphate synthase
Crystal structure of Indole-3-glycerol phosphate synthase from Brucella melitensis
 0.44 14.44 0.79 17-228 X-ray 2.15 homo-dimer HHblits 0.26
2dzp.1.A
Tryptophan synthase alpha chain
Structure of mutant tryptophan synthase alpha-subunit (D17N) from a hyperthermophile, Pyrococcus furiosus
 0.40 14.67 0.77 15-215 X-ray 2.40 monomer HHblits 0.27
5g2h.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
S. enterica HisA with mutation L169R
 0.39 16.94 0.77 13-216 X-ray 1.90 homo-dimer HHblits 0.28
1wdw.1.A
Tryptophan synthase alpha chain
Structural basis of mutual activation of the tryptophan synthase a2b2 complex from a hyperthermophile, Pyrococcus furiosus
 0.40 14.67 0.77 15-215 X-ray 3.00 hetero-oligomer 2 x PLP HHblits 0.27
1geq.1.A
TRYPTOPHAN SYNTHASE ALPHA-SUBUNIT
Entropic stabilization of the tryptophan synthase A-subunit from a hyperthermophile, pyrococcus furiosus: X-ray analysis and calorimetry
 0.40 14.67 0.77 15-215 X-ray 2.00 monomer HHblits 0.27
2dzw.1.A
Tryptophan synthase alpha chain
Structure of mutant tryptophan synthase alpha-subunit (E244A) from a hyperthermophile, Pyrococcus furiosus
 0.40 14.67 0.77 15-215 X-ray 2.40 monomer HHblits 0.27
4qcc.1.A
2-dehydro-3-deoxy-6-phosphogalactonate aldolase, peptidyl-prolyl cis-trans isomerase chimera
Structure of a cube-shaped, highly porous protein cage designed by fusing symmetric oligomeric domains
 0.42 14.13 0.77 1-219 X-ray 7.08 homo-24-mer HHblits 0.27
2dzs.1.A
Tryptophan synthase alpha chain
Structure of mutant tryptophan synthase alpha-subunit (E103A) from a hyperthermophile, Pyrococcus furiosus
 0.40 14.67 0.77 15-215 X-ray 2.40 monomer HHblits 0.27
1ep3.1.C
DIHYDROOROTATE DEHYDROGENASE B (PYRD SUBUNIT)
CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B. DATA COLLECTED UNDER CRYOGENIC CONDITIONS.
 0.37 14.84 0.76 4-228 X-ray 2.10 hetero-2-2-mer 2 x FMN, 2 x FAD, 2 x FES HHblits 0.28
1ep2.1.C
DIHYDROOROTATE DEHYDROGENASE B (PYRD SUBUNIT)
CRYSTAL STRUCTURE OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE B COMPLEXED WITH OROTATE
 0.37 14.84 0.76 4-228 X-ray 2.40 hetero-2-2-mer 2 x FMN, 2 x ORO, 2 x FAD, 2 x FES HHblits 0.28
7pji.1.A
Inosine-5'-monophosphate dehydrogenase
Crystal structure of Pseudomonas aeruginosa guaB (IMP dehydrogenase) bound to ATP and GDP at 1.65A resolution
 0.32 14.59 0.78 18-214 X-ray 1.65 homo-octamer 8 x ATP, 8 x GDP, 8 x IMP, 8 x MG, 8 x K HHblits 0.26
5ue9.1.A
Dihydroorotate dehydrogenase
WT DHODB with orotate bound
 0.37 13.74 0.76 4-228 X-ray 2.72 hetero-2-2-mer 2 x FMN, 2 x ORO, 2 x FAD, 2 x FES HHblits 0.27
2y7f.1.A
3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME
Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from C. Cloacamonas acidaminovorans in complex with the substrate 3- keto-5-aminohexanoate
 0.32 19.10 0.75 11-207 X-ray 1.75 homo-tetramer 4 x ZN, 4 x KMH, 1 x MG HHblits 0.29
2y7d.1.D
3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME
Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from Candidatus Cloacamonas acidaminovorans (orthorombic form)
 0.32 19.10 0.75 11-207 X-ray 1.59 homo-tetramer 4 x ZN HHblits 0.29
3og3.1.A
Imidazole glycerol phosphate synthase subunit hisF
Crystal structure of an artificial thermostable (BA)8-barrel protein from identical half barrels
 0.41 17.13 0.76 18-217 X-ray 2.08 monomer HHblits 0.27
7qc6.1.A
Imidazole glycerol phosphate synthase subunit HisF
HisF_C9A_L50H_I52H mutant (apo) from T. maritima
 0.39 16.67 0.76 23-221 X-ray 2.10 monomer 1 x DTT HHblits 0.28
4gj1.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Crystal structure of 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (hisA).
 0.41 16.95 0.74 22-217 X-ray 2.15 monomer HHblits 0.29
3iiv.1.A
KE7 KE7_R7_1/3H
Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series
 0.40 14.84 0.76 22-222 X-ray 1.80 monomer HHblits 0.26
3iiv.2.A
KE7 KE7_R7_1/3H
Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series
 0.40 14.84 0.76 22-222 X-ray 1.80 monomer 1 x MG HHblits 0.26
4lt9.1.A
Engineered Protein OR404
Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR404
 0.39 14.61 0.75 24-223 X-ray 2.15 monomer HHblits 0.28
4fx7.1.A
Imidazole glycerol phosphate synthase subunit HisF
Structure of Sym2 D9V+D55V+D130V+D176V
 0.42 17.88 0.75 17-216 X-ray 2.08 monomer 2 x PI HHblits 0.28
2w79.1.A
1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE
Establishing wild-type levels of catalytic activity on natural and artificial (ba)8-barrel protein scaffolds
 0.38 12.85 0.75 18-217 X-ray 1.85 monomer HHblits 0.27
2w79.2.A
1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE
Establishing wild-type levels of catalytic activity on natural and artificial (ba)8-barrel protein scaffolds
 0.37 12.85 0.75 18-217 X-ray 1.85 monomer HHblits 0.27
2a0n.1.A
Imidazole glycerol phosphate synthase subunit hisF
Crystal structure of Imidazole glycerol phosphate synthase subunit hisF (EC 4.1.3.-) (tm1036) from Thermotoga maritima at 1.64 A resolution
 0.40 17.32 0.75 20-217 X-ray 1.64 monomer HHblits 0.27
7pd1.1.A
Thiazole biosynthesis protein ThiH
Crystal structure of the L-tyrosine-bound radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans
 0.31 12.78 0.76 13-209 X-ray 1.27 monomer 1 x SF4, 1 x 5AD, 1 x MET, 1 x TYR, 1 x K, 6 x BR HHblits 0.27
7pd1.2.A
Thiazole biosynthesis protein ThiH
Crystal structure of the L-tyrosine-bound radical SAM tyrosine lyase ThiH (2-iminoacetate synthase) from Thermosinus carboxydivorans
 0.31 12.78 0.76 13-209 X-ray 1.27 monomer 1 x SF4, 1 x 5AD, 1 x MET, 1 x TYR, 3 x BR HHblits 0.27
5d33.1.A
de novo kemp eliminase KE07 round 7
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 12 round 7
 0.40 14.92 0.76 23-222 X-ray 1.59 homo-dimer HHblits 0.26
5d33.1.B
de novo kemp eliminase KE07 round 7
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 12 round 7
 0.40 14.92 0.76 23-222 X-ray 1.59 homo-dimer HHblits 0.26
5abt.1.A
1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE
S.enterica HisA mutant D7N, G102A, V106M, D176A
 0.39 16.95 0.74 22-216 X-ray 1.65 monomer 1 x GUO HHblits 0.28
6c8b.1.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 23 round 6
 0.41 14.92 0.76 20-219 X-ray 1.61 monomer HHblits 0.26
6c8b.2.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 23 round 6
 0.41 14.92 0.76 20-219 X-ray 1.61 monomer HHblits 0.26
6bma.1.A
Indole-3-glycerol phosphate synthase
The crystal structure of indole-3-glycerol phosphate synthase from Campylobacter jejuni subsp. jejuni NCTC 11168
 0.44 13.81 0.76 18-223 X-ray 1.98 homo-dimer 2 x K HHblits 0.26
5j6f.1.A
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, chorismate mutase-isozyme 3
Crystal structure of DAH7PS-CM complex from Geobacillus sp. with prephenate
 0.34 13.19 0.76 13-210 X-ray 2.75 homo-tetramer 4 x MN, 4 x PRE HHblits 0.26
5j6f.1.B
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, chorismate mutase-isozyme 3
Crystal structure of DAH7PS-CM complex from Geobacillus sp. with prephenate
 0.33 13.19 0.76 13-210 X-ray 2.75 homo-tetramer 4 x MN, 4 x PRE HHblits 0.26
1r30.1.A
Biotin synthase
The Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme
 0.38 14.04 0.75 14-209 X-ray 3.40 homo-dimer 2 x SAM, 2 x SF4, 2 x FES, 2 x DTB HHblits 0.27
1vc4.1.A
Indole-3-Glycerol Phosphate Synthase
Crystal Structure of Indole-3-Glycerol Phosphate Synthase (TrpC) from Thermus Thermophilus At 1.8 A Resolution
 0.43 11.54 0.76 17-224 X-ray 1.80 monomer HHblits 0.26
1vc4.2.A
Indole-3-Glycerol Phosphate Synthase
Crystal Structure of Indole-3-Glycerol Phosphate Synthase (TrpC) from Thermus Thermophilus At 1.8 A Resolution
 0.43 11.54 0.76 17-224 X-ray 1.80 monomer HHblits 0.26
5xse.1.A
KHG/KDPG aldolase
Crystal structure of the 2-keto-3-deoxy-6-phosphogluconate aldolase of Zymomonas mobilis ZM4
 0.34 17.92 0.73 4-214 X-ray 1.80 homo-trimer HHblits 0.29
4bk9.1.A
2-DEHYDRO-3-DEOXYPHOSPHOGLUCONATE ALDOLASE/4-HYDROXY-2-OXO GLUTARATE ALDOLASE
Crystal structure of 2-keto-3-deoxy-6-phospho-gluconate aldolase from Zymomonas mobilis ATCC 29191
 0.35 17.34 0.73 4-214 X-ray 2.77 homo-trimer HHblits 0.29
5xsf.1.A
KHG/KDPG aldolase
Crystal structure of the 2-keto-3-deoxy-6-phosphogluconate aldolase of Zymomonas mobilis ZM4 with 3-phosphoglycerate
 0.34 17.34 0.73 5-215 X-ray 1.96 homo-trimer 3 x 3PG, 3 x 3PY HHblits 0.29
2w6r.1.A
IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISF
Crystal structure of an artificial (ba)8-barrel protein designed from identical half barrels
 0.37 17.98 0.75 20-216 X-ray 2.10 monomer HHblits 0.27
2cff.1.A
1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE
Crystal Structure Of N-((5'-Phosphoribosyl)-Formimino)-5- Aminoimidazol-4-Carboxamid Ribonucleotid Isomerase mutant D127V (Ec 3. 1.3.15, Hisa)
 0.36 13.14 0.74 21-216 X-ray 2.50 monomer HHblits 0.28
2cff.2.A
1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE
Crystal Structure Of N-((5'-Phosphoribosyl)-Formimino)-5- Aminoimidazol-4-Carboxamid Ribonucleotid Isomerase mutant D127V (Ec 3. 1.3.15, Hisa)
 0.37 13.14 0.74 21-216 X-ray 2.50 monomer HHblits 0.28
2y85.1.A
PHOSPHORIBOSYL ISOMERASE A
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE WITH BOUND RCDRP
 0.37 14.20 0.74 21-216 X-ray 2.40 monomer 1 x 137 HHblits 0.27
3zs4.1.A
PHOSPHORIBOSYL ISOMERASE A
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE WITH BOUND PRFAR
 0.36 14.20 0.74 21-216 X-ray 1.90 monomer 1 x 1PR HHblits 0.27
6ovi.1.A
Keto-deoxy-phosphogluconate aldolase
Crystal Structure of KDPG Aldolase from Legionella Pneumophila with pyruvate captured at low pH as a covalent carbinolamine intermediate
 0.36 12.99 0.74 4-217 X-ray 1.60 homo-trimer 3 x PVO HHblits 0.27
6dc1.1.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.38 14.53 0.75 19-216 X-ray 2.68 monomer 1 x 6VP, 1 x B3P HHblits 0.26
6cai.2.A
Kemp Eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 24 round 7
 0.39 14.53 0.75 19-216 X-ray 1.82 monomer HHblits 0.26
6cai.1.A
Kemp Eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 24 round 7
 0.40 14.53 0.75 19-216 X-ray 1.82 monomer HHblits 0.26
6dc1.3.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.39 14.53 0.75 19-216 X-ray 2.68 monomer 1 x B3P HHblits 0.26
6dc1.4.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.39 14.53 0.75 19-216 X-ray 2.68 monomer HHblits 0.26
6dc1.5.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.40 14.53 0.75 19-216 X-ray 2.68 monomer HHblits 0.26
6dc1.6.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.39 14.53 0.75 19-216 X-ray 2.68 monomer HHblits 0.26
6dc1.7.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.39 14.53 0.75 19-216 X-ray 2.68 monomer HHblits 0.26
6dc1.8.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.38 14.53 0.75 19-216 X-ray 2.68 monomer 1 x 6VP HHblits 0.26
6dc1.9.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.37 14.53 0.75 19-216 X-ray 2.68 monomer HHblits 0.26
6dc1.10.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.38 14.53 0.75 19-216 X-ray 2.68 monomer HHblits 0.26
6dc1.11.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.39 14.53 0.75 19-216 X-ray 2.68 monomer 1 x 6VP HHblits 0.26
6dc1.12.A
Kemp eliminase KE07
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7
 0.40 14.53 0.75 19-216 X-ray 2.68 monomer HHblits 0.26
5d37.1.A
De novo kemp eliminase KE07 round 7
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 16 round 7
 0.40 15.17 0.75 21-217 X-ray 2.04 homo-dimer HHblits 0.26
5d37.1.B
De novo kemp eliminase KE07 round 7
Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 16 round 7
 0.40 15.17 0.75 21-217 X-ray 2.04 homo-dimer HHblits 0.26
5im5.1.P
Designed Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase
Crystal structure of designed two-component self-assembling icosahedral cage I53-40
 0.37 13.41 0.75 3-216 X-ray 3.70 hetero-15-15-mer HHblits 0.26
1i4n.1.A
INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
CRYSTAL STRUCTURE OF INDOLEGLYCEROL PHOSPHATE SYNTHASE FROM THERMOTOGA MARITIMA
 0.41 13.07 0.74 23-226 X-ray 2.50 monomer HHblits 0.27
1qo2.1.A
?
Crystal structure of N-((5'-phosphoribosyl)-formimino)-5-aminoimidazol-4-carboxamid ribonucleotid isomerase (EC 3.1.3.15, HisA)
 0.34 13.29 0.73 23-216 X-ray 1.85 monomer HHblits 0.28
1qo2.2.A
?
Crystal structure of N-((5'-phosphoribosyl)-formimino)-5-aminoimidazol-4-carboxamid ribonucleotid isomerase (EC 3.1.3.15, HisA)
 0.34 13.29 0.73 23-216 X-ray 1.85 monomer HHblits 0.28
1j5t.1.A
INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
Crystal structure of indole-3-glycerol phosphate synthase (TM0140) from Thermotoga maritima at 3.0 A resolution
 0.41 13.07 0.74 23-226 X-ray 3.00 monomer HHblits 0.27
4iww.1.A
Unnatural Amino Acid Mediated Metalloprotein
Computational Design of an Unnatural Amino Acid Metalloprotein with Atomic Level Accuracy
 0.41 15.03 0.73 23-221 X-ray 2.30 monomer 1 x CO HHblits 0.28
4ix0.1.A
Unnatural Amino Acid Mediated Metalloprotein
Computational Design of an Unnatural Amino Acid Metalloprotein with Atomic Level Accuracy
 0.41 15.03 0.73 23-221 X-ray 2.50 monomer 1 x NI HHblits 0.28
2y89.1.A
PHOSPHORIBOSYL ISOMERASE A
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE A (VARIANT D11N)
 0.36 14.37 0.73 22-215 X-ray 2.50 monomer HHblits 0.28
2y88.1.A
PHOSPHORIBOSYL ISOMERASE A
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PHOSPHORIBOSYL ISOMERASE (VARIANT D11N) WITH BOUND PRFAR
 0.36 14.37 0.73 22-215 X-ray 1.33 monomer 1 x 2ER HHblits 0.28
6tfa.1.A
F112L RA95.5-8F
Structure of the engineered retro-aldolase RA95.5-8F F112L
 0.36 13.14 0.74 25-224 X-ray 2.16 monomer HHblits 0.27
1mxs.1.A
KDPG Aldolase
Crystal structure of 2-keto-3-deoxy-6-phosphogluconate (KDPG) aldolase from Pseudomonas putida.
 0.38 11.86 0.74 4-216 X-ray 2.20 homo-trimer HHblits 0.26
1jcm.1.A
INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE
TRPC STABILITY MUTANT CONTAINING AN ENGINEERED DISULPHIDE BRIDGE AND IN COMPLEX WITH A CDRP-RELATED SUBSTRATE
 0.42 9.60 0.74 23-226 X-ray 2.10 monomer 1 x 137 HHblits 0.25
5an7.1.A
RA95.5-8F
Structure of the engineered retro-aldolase RA95.5-8F with a bound 1,3-diketone inhibitor
 0.37 13.22 0.73 25-223 X-ray 1.10 monomer 1 x LLK HHblits 0.27
4pa8.1.A
retro-aldolase
Crystal structure of a de novo retro-aldolase catalyzing asymmetric Michael additions, with a covalently bound product analog
 0.38 14.04 0.72 28-223 X-ray 1.20 monomer 1 x 2K6 HHblits 0.28
6ncs.1.A
N-acetylneuraminic acid (Sialic acid) synthetase
Crystal structure of N-acetylneuraminic acid (Sialic acid) synthetase from Leptospira borgpetersenii serovar Hardjo-bovis in complex with citrate
 0.32 12.72 0.73 14-204 X-ray 1.80 homo-dimer 2 x MN, 1 x TAR HHblits 0.27
4ou1.1.A
Retro-aldolase, design RA114
Crystal structure of a computationally designed retro-aldolase covalently bound to folding probe 1 [(6-methoxynaphthalen-2-yl)(oxiran-2-yl)methanol]
 0.38 14.71 0.71 29-223 X-ray 1.25 monomer 1 x 2V7, 1 x BEZ HHblits 0.28
4pek.1.A
Retro-aldolase
Crystal structure of a computationally designed retro-aldolase, RA114.3
 0.39 14.71 0.71 29-223 X-ray 1.60 monomer HHblits 0.28
4lny.1.A
Engineered Protein OR422
Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR422
 0.39 14.04 0.72 28-223 X-ray 1.93 monomer 6 x CD HHblits 0.27
5k7j.1.A
Indole-3-glycerol phosphate synthase
Structure of designed zinc binding protein ZE2 bound to Zn2+
 0.40 14.79 0.71 24-218 X-ray 1.39 monomer 1 x ZN HHblits 0.28
3o6y.1.A
Retro-Aldolase
Robust computational design, optimization, and structural characterization of retroaldol enzymes
 0.37 13.45 0.72 28-223 X-ray 2.09 monomer HHblits 0.27
3uxa.1.A
Kemp eliminase KE59 R1 7/10H
Designed protein KE59 R1 7/10H
 0.41 15.48 0.71 24-217 X-ray 2.50 monomer HHblits 0.28
3qz6.1.A
HpcH/HpaI aldolase
The crystal structure of HpcH/HpaI aldolase from Desulfitobacterium hafniense DCB-2
 0.32 13.45 0.72 22-209 X-ray 2.00 homo-dimer 2 x ZN HHblits 0.27
3tc7.1.A
Indole-3-glycerol phosphate synthase
Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR62.
 0.38 14.88 0.71 29-221 X-ray 1.50 monomer HHblits 0.28
3nxf.1.A
Retro-Aldolase
Robust computational design, optimization, and structural characterization of retroaldol enzymes
 0.37 13.45 0.72 28-223 X-ray 2.40 monomer HHblits 0.27
4utt.1.A
PUTATIVE N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE
Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens
 0.41 14.53 0.72 15-216 X-ray 1.71 hetero-1-1-mer HHblits 0.26
4utt.1.B
PUTATIVE N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE
Structural characterisation of NanE, ManNac6P C2 epimerase, from Clostridium perfingens
 0.41 14.53 0.72 15-216 X-ray 1.71 hetero-1-1-mer HHblits 0.26
1dxe.1.A
2-DEHYDRO-3-DEOXY-GALACTARATE ALDOLASE
2-DEHYDRO-3-DEOXY-GALACTARATE ALDOLASE FROM ESCHERICHIA COLI
 0.32 15.98 0.71 23-209 X-ray 1.80 homo-hexamer 6 x MG HHblits 0.27
3vzx.1.A
Heptaprenylglyceryl phosphate synthase
Crystal structure of PcrB from bacillus subtilis subap. subtilis str. 168
 0.28 21.95 0.69 19-215 X-ray 1.54 homo-dimer 10 x MG HHblits 0.30
3vzx.1.B
Heptaprenylglyceryl phosphate synthase
Crystal structure of PcrB from bacillus subtilis subap. subtilis str. 168
 0.28 21.95 0.69 19-215 X-ray 1.54 homo-dimer 10 x MG HHblits 0.30
4utu.1.A
N-ACETYLMANNOSAMINE-6-PHOSPHATE 2-EPIMERASE
Structural and biochemical characterization of the N- acetylmannosamine-6-phosphate 2-epimerase from Clostridium perfringens
 0.40 15.20 0.72 16-216 X-ray 1.45 homo-dimer 2 x LRY HHblits 0.27
3nyz.1.A
Indole-3-glycerol phosphate synthase
Crystal Structure of Kemp Elimination Catalyst 1A53-2
 0.38 15.48 0.71 24-217 X-ray 1.51 monomer HHblits 0.28
3nyz.2.A
Indole-3-glycerol phosphate synthase
Crystal Structure of Kemp Elimination Catalyst 1A53-2
 0.39 15.48 0.71 24-217 X-ray 1.51 monomer HHblits 0.28
3nz1.1.A
Indole-3-glycerol phosphate synthase
Crystal Structure of Kemp Elimination Catalyst 1A53-2 Complexed with Transition State Analog 5-Nitro Benzotriazole
 0.39 15.48 0.71 24-217 X-ray 1.56 monomer 1 x 3NY, 3 x TLA HHblits 0.28
2v5j.1.A
2,4-DIHYDROXYHEPT-2-ENE-1,7-DIOIC ACID ALDOLASE
Apo Class II aldolase HpcH
 0.31 11.18 0.71 22-209 X-ray 1.60 homo-hexamer HHblits 0.27
2c3z.1.A
INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
Crystal structure of a truncated variant of indole-3-glycerol phosphate synthase from Sulfolobus solfataricus
 0.39 14.88 0.71 24-217 X-ray 2.80 monomer HHblits 0.28
4a29.1.A
ENGINEERED RETRO-ALDOL ENZYME RA95.0
Structure of the engineered retro-aldolase RA95.0
 0.37 14.88 0.71 28-220 X-ray 1.10 monomer 1 x 3NK, 1 x MLT HHblits 0.28
1viz.1.A
PcrB protein homolog
Crystal structure of an hypothetical protein
 0.27 22.09 0.68 20-215 X-ray 1.85 monomer HHblits 0.30
8fmc.1.A
Kemp Eliminase 1A53-core
Crystal Structure of Kemp Eliminase 1A53-core in unbound state
 0.39 14.97 0.70 24-216 X-ray 2.36 monomer 1 x MES HHblits 0.28
1a53.1.A
INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE
COMPLEX OF INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE FROM SULFOLOBUS SOLFATARICUS WITH INDOLE-3-GLYCEROLPHOSPHATE AT 2.0 A RESOLUTION
 0.40 15.06 0.70 28-218 X-ray 2.00 monomer 1 x IGP HHblits 0.28
3uy7.1.A
Kemp eliminase KE59 R1 7/10H
Designed protein KE59 R1 7/10H with G130S mutation
 0.40 15.76 0.69 28-217 X-ray 1.45 monomer HHblits 0.29
6nw4.1.A
Indole-3-glycerol phosphate synthase
Evolution of a computationally designed Kemp eliminase
 0.41 15.66 0.70 28-218 X-ray 3.00 monomer 1 x 6NT HHblits 0.28
4a2s.1.A
INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
Structure of the engineered retro-aldolase RA95.5
 0.37 15.06 0.70 29-219 X-ray 1.40 monomer 2 x 3NK HHblits 0.28
4a2r.1.A
INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
Structure of the engineered retro-aldolase RA95.5-5
 0.37 14.46 0.70 29-219 X-ray 1.30 monomer 1 x 3NK HHblits 0.28
3uy8.1.A
Kemp eliminase KE59 R5_11/5F
Designed protein KE59 R5_11/5F
 0.37 16.36 0.69 28-218 X-ray 2.41 monomer HHblits 0.28
4jdy.1.A
Pyridoxal biosynthesis lyase PdxS
Crystal structure of Rv2606c
 0.29 13.61 0.71 20-233 X-ray 1.80 homo-12-mer HHblits 0.26
1jul.1.A
INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE FROM SULFOLOBUS SOLFATARICUS IN A SECOND ORTHORHOMBIC CRYSTAL FORM
 0.39 15.15 0.69 29-218 X-ray 2.00 monomer 1 x MES HHblits 0.28
1juk.1.A
INDOLE-3-GLYCEROL PHOSPHATE SYNTHASE
INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE FROM SULFOLOBUS SOLFATARICUS IN A TRIGONAL CRYSTAL FORM
 0.39 15.15 0.69 29-218 X-ray 2.50 monomer HHblits 0.28
3uz5.1.A
Kemp eliminase KE59 R13 3/11H
Designed protein KE59 R13 3/11H
 0.38 17.18 0.68 28-215 X-ray 1.90 monomer 1 x 0CU HHblits 0.29
6tf8.2.A
RA95.5-8F_133F
Structure of the engineered artificial aldolase I133F RA95.5-8F with a bound substrate, pentan-2-one
 0.34 13.86 0.70 25-215 X-ray 1.90 monomer HHblits 0.28
6tf8.1.A
RA95.5-8F_133F
Structure of the engineered artificial aldolase I133F RA95.5-8F with a bound substrate, pentan-2-one
 0.35 13.86 0.70 25-215 X-ray 1.90 monomer HHblits 0.28
3hoj.1.A
RETROALDOLASE-22
Crystal Structure of a Novel Engineered Retroaldolase: RA-22
 0.38 14.55 0.69 29-218 X-ray 2.20 monomer HHblits 0.28
3uyc.1.A
Kemp eliminase KE59 R8_2/7A
Designed protein KE59 R8_2/7A
 0.36 16.56 0.68 28-216 X-ray 2.20 monomer HHblits 0.29
4b5x.1.A
4-HYDROXY-2-OXO-HEPTANE-1,7-DIOATE ALDOLASE
Crystal structures of divalent metal dependent pyruvate aldolase (HpaI), mutant D42A
 0.29 11.45 0.70 23-209 X-ray 1.80 homo-hexamer HHblits 0.27
3w01.1.B
Heptaprenylglyceryl phosphate synthase
Crystal structure of PcrB complexed with PEG from Staphylococcus aureus subsp. aureus Mu3
 0.27 15.34 0.68 20-215 X-ray 1.54 homo-dimer HHblits 0.28
3w01.1.A
Heptaprenylglyceryl phosphate synthase
Crystal structure of PcrB complexed with PEG from Staphylococcus aureus subsp. aureus Mu3
 0.28 15.34 0.68 20-215 X-ray 1.54 homo-dimer HHblits 0.28
3w02.1.A
Heptaprenylglyceryl phosphate synthase
Crystal structure of PcrB complexed with SO4 from Staphylococcus aureus subsp. aureus Mu3
 0.28 15.34 0.68 20-215 X-ray 2.98 homo-dimer HHblits 0.28
7etx.1.A
Tryptophan biosynthesis protein TrpCF
Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (TrpC) from corynebacterium glutamicum
 0.30 19.75 0.68 8-204 X-ray 2.10 homo-dimer HHblits 0.28
7ety.1.A
Tryptophan biosynthesis protein TrpCF
Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpC) from Corynebacterium glutamicum in complex with reduced 1-(O-carboxyphenylamino)-1-deoxyribulose 5-phosphate (rCdRP)
 0.30 19.75 0.68 8-204 X-ray 2.21 homo-dimer 4 x 137 HHblits 0.28
4j9j.1.A
Imidazole glycerol phosphate synthase subunit HisF
Structure of designed HisF
 0.32 18.52 0.68 20-202 X-ray 2.30 monomer HHblits 0.28
1pii.1.A
N-(5'PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
THREE-DIMENSIONAL STRUCTURE OF THE BIFUNCTIONAL ENZYME PHOSPHORIBOSYLANTHRANILATE ISOMERASE: INDOLEGLYCEROLPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI REFINED AT 2.0 ANGSTROMS RESOLUTION
 0.30 16.36 0.69 8-205 X-ray 2.00 monomer HHblits 0.26
2agk.1.A
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase
Structure of S. cerevisiae His6 protein
 0.26 10.98 0.69 25-212 X-ray 1.30 monomer HHblits 0.25
1x7i.1.A
Copper homeostasis protein cutC
Crystal structure of the native copper homeostasis protein (cutCm) with calcium binding from Shigella flexneri 2a str. 301
 0.26 17.42 0.65 26-208 X-ray 1.70 homo-dimer 1 x CA HHblits 0.28
1twd.1.B
Copper homeostasis protein cutC
Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33
 0.27 17.42 0.65 26-208 X-ray 1.70 homo-dimer HHblits 0.28
1twd.1.A
Copper homeostasis protein cutC
Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33
 0.27 17.42 0.65 26-208 X-ray 1.70 homo-dimer HHblits 0.28
1x7i.1.B
Copper homeostasis protein cutC
Crystal structure of the native copper homeostasis protein (cutCm) with calcium binding from Shigella flexneri 2a str. 301
 0.27 17.42 0.65 26-208 X-ray 1.70 homo-dimer 1 x CA HHblits 0.28
1uum.1.A
DIHYDROOROTATE DEHYDROGENASE
Rat dihydroorotate dehydrogenase (DHOD)in complex with atovaquone
 0.31 14.94 0.65 75-228 X-ray 2.30 monomer 1 x FMN, 1 x ORO, 1 x AFI, 1 x BOG HHblits 0.28
1uuo.1.A
DIHYDROOROTATE DEHYDROGENASE
Rat dihydroorotate dehydrogenase (DHOD)in complex with brequinar
 0.31 14.94 0.65 75-228 X-ray 2.44 monomer 1 x BRF, 1 x FMN, 1 x ORO, 1 x NI HHblits 0.28
8cso.2.B
Orotidine 5'-phosphate decarboxylase
Crystal Structure of Orotidine 5'-phosphate decarboxylase from Klebsiella pneumoniae in complex with Uridine-5'-monophosphate
 0.26 18.42 0.64 74-229 X-ray 2.60 homo-dimer 1 x U5P HHblits 0.29
8cso.1.A
Orotidine 5'-phosphate decarboxylase
Crystal Structure of Orotidine 5'-phosphate decarboxylase from Klebsiella pneumoniae in complex with Uridine-5'-monophosphate
 0.26 18.42 0.64 74-229 X-ray 2.60 homo-dimer 2 x U5P HHblits 0.29
5ea9.1.A
Dihydroorotate dehydrogenase (fumarate)
Crystal Structure of Trypanosoma cruzi Dihydroorotate Dehydrogenase in Complex with Neq0130
 0.28 14.84 0.65 74-229 X-ray 1.71 homo-dimer 2 x 5LM, 2 x FMN, 2 x NCO HHblits 0.27
3w88.1.B
Dihydroorotate dehydrogenase (fumarate)
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with SH-1-200
 0.29 14.84 0.65 74-229 X-ray 1.40 homo-dimer 2 x W88, 4 x CAC, 2 x FMN, 2 x NCO HHblits 0.27
6dwg.1.A
Dihydroorotate dehydrogenase (fumarate)
Crystal structure of Leishmania major dihydroorotate dehydrogenase mutant Q139A
 0.29 12.82 0.66 74-231 X-ray 1.90 homo-dimer 2 x FMN, 1 x NI HHblits 0.27
2fpt.1.A
Dihydroorotate dehydrogenase, mitochondrial
Dual Binding Mode of a Novel Series of DHODH inhibitors
 0.29 13.55 0.65 74-228 X-ray 2.40 monomer 1 x FMN, 1 x ORO, 1 x ILB HHblits 0.27
2b0m.1.A
Dihydroorotate dehydrogenase, mitochondrial
Human dihydroorotate dehydrogenase bound to a novel inhibitor
 0.30 12.90 0.65 74-228 X-ray 2.00 monomer 1 x 201, 1 x FMN, 1 x ORO HHblits 0.27
5k9c.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of human dihydroorotate dehydrogenase with ML390
 0.29 12.99 0.65 74-227 X-ray 1.66 monomer 1 x FNR, 1 x ORO, 1 x MLJ HHblits 0.27
1jrc.1.A
dihydroorotate dehydrogenase A
The N67A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
 0.27 12.90 0.65 74-228 X-ray 1.80 homo-dimer 2 x FMN, 2 x ORO HHblits 0.26
3u2o.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Dihydroorotate Dehydrogenase (DHODH) crystal structure in complex with small molecule inhibitor
 0.29 12.99 0.65 74-227 X-ray 2.18 monomer 1 x FMN, 1 x ORO, 1 x 03U HHblits 0.27
6fmd.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Targeting myeloid differentiation using potent human dihydroorotate dehydrogenase (hDHODH) inhibitors based on 2-hydroxypyrazolo[1,5-a]pyridine scaffold
 0.30 12.99 0.65 74-227 X-ray 1.58 monomer 1 x DUH, 1 x FMN, 1 x ORO HHblits 0.27
6vnd.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Quaternary Complex of human dihydroorotate dehydrogenase (DHODH) with flavin mononucleotide (FMN), orotic acid and AG-636
 0.29 12.99 0.65 74-227 X-ray 1.97 monomer 1 x R4P, 2 x DET, 2 x DDQ, 1 x FMN, 1 x ORO HHblits 0.27
6oc0.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of human DHODH with OSU-03012
 0.30 12.99 0.65 74-227 X-ray 1.40 monomer 1 x ORO, 1 x FMN, 1 x M4J HHblits 0.27
6oc1.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of human DHODH with TAK-632
 0.29 12.99 0.65 74-227 X-ray 2.70 monomer 1 x ORO, 1 x FMN, 1 x 1SU HHblits 0.27
3kvm.1.A
Dihydroorotate dehydrogenase, mitochondrial
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with amino-benzoic acid inhibitor 951 at 2.00A resolution
 0.30 12.99 0.65 74-227 X-ray 2.00 monomer 1 x FMN, 1 x DOR, 1 x DET, 1 x 951 HHblits 0.27
5mvd.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of potent human Dihydroorotate Dehydrogenase inhibitors based on hydroxylated azole scaffolds
 0.29 12.99 0.65 74-227 X-ray 1.95 monomer 1 x FMN, 1 x ORO, 1 x U91 HHblits 0.27
3oix.1.A
Putative dihydroorotate dehydrogenase; dihydroorotate oxidase
Crystal structure of the putative dihydroorotate dehydrogenase from Streptococcus mutans
 0.26 12.34 0.65 75-228 X-ray 2.40 homo-tetramer 4 x FMN HHblits 0.27
4dbd.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of orotidine 5'-monophosphate decarboxylase from Sulfolobus solfataricus
 0.26 14.38 0.64 74-234 X-ray 1.70 homo-dimer HHblits 0.27
2wv8.1.A
DIHYDROOROTATE DEHYDROGENASE, MITOCHONDRIAL
Complex of human dihydroorotate dehydrogenase with the inhibitor 221290
 0.29 12.99 0.65 74-227 X-ray 1.90 monomer 1 x FMN, 1 x ORO, 1 x VGN, 1 x DDQ HHblits 0.27
6lzl.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with Piperine
 0.29 12.99 0.65 74-227 X-ray 1.98 monomer 1 x ORO, 1 x FMN, 1 x AYR HHblits 0.27
3sfk.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM267
 0.30 11.69 0.65 75-228 X-ray 2.95 monomer 1 x D67, 1 x FMN, 1 x ORO HHblits 0.27
6i4b.1.A
Dihydroorotate dehydrogenase
Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) co-crystallized with 3-Hydroxy-1-methyl-5-((3-(trifluoromethyl)phenoxy)methyl)-1H-pyrazole-4-carboxylic acid
 0.29 11.69 0.65 75-228 X-ray 1.98 monomer 1 x FMN, 1 x ORO, 1 x E2N HHblits 0.27
3i65.1.A
Dihydroorotate dehydrogenase homolog, mitochondrial
Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM1
 0.29 11.69 0.65 75-228 X-ray 2.00 monomer 1 x JZ8, 1 x FMN, 1 x ORO, 1 x LDA HHblits 0.27
3i6r.1.A
Dihydroorotate dehydrogenase homolog, mitochondrial
Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM74
 0.29 11.69 0.65 75-228 X-ray 2.50 monomer 1 x J5Z, 1 x FMN, 1 x ORO HHblits 0.27
3i68.1.A
Dihydroorotate dehydrogenase homolog, mitochondrial
Plasmodium falciparum dihydroorotate dehydrogenase bound with triazolopyrimidine-based inhibitor DSM2
 0.29 11.69 0.65 75-228 X-ray 2.40 monomer 1 x J4Z, 1 x FMN, 1 x ORO HHblits 0.27
6gjg.2.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Plasmodium falciparum dihydroorotate dehydrogenase DHODH in complex with 3,6-dimethyl-N-(4-(trifluoromethyl)phenyl)-(1,2)oxazolo(5,4-d)pyrimidin-4-amine
 0.29 11.69 0.65 75-228 X-ray 1.99 monomer 1 x FMN, 1 x ORO, 1 x F1T HHblits 0.26
5del.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM59
 0.29 11.69 0.65 75-228 X-ray 2.20 monomer 1 x FMN, 1 x ORO, 1 x D59, 1 x LDA HHblits 0.26
4rx0.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM265
 0.29 11.69 0.65 75-228 X-ray 2.25 monomer 1 x D65, 1 x FMN, 1 x ORO HHblits 0.26
6vtn.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM557
 0.28 11.69 0.65 75-228 X-ray 2.25 monomer 1 x RL7, 1 x FMN, 1 x ORO HHblits 0.26
7l0k.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM784 (3-(1-(3-methyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-pyrrole-2-carboxamido)ethyl)-1H-pyrazole-5-carboxamide)
 0.28 11.69 0.65 75-228 X-ray 1.96 monomer 1 x XE7, 1 x FMN, 1 x ORO HHblits 0.26
7kyk.3.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM589 (ethyl 3-methyl-4-((4-(trifluoromethyl)benzo[d]oxazol-7-yl)methyl)-1H-pyrrole-2-carboxylate)
 0.29 11.69 0.65 75-228 X-ray 2.15 monomer 1 x XAJ, 1 x FMN, 1 x ORO HHblits 0.26
7kyk.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM589 (ethyl 3-methyl-4-((4-(trifluoromethyl)benzo[d]oxazol-7-yl)methyl)-1H-pyrrole-2-carboxylate)
 0.29 11.69 0.65 75-228 X-ray 2.15 monomer 1 x XAJ, 1 x FMN, 1 x ORO HHblits 0.26
7kzy.2.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM778 (3-methyl-N-(1-(5-methyl-1H-pyrazol-3-yl)ethyl)-4-(1-(6-(trifluoromethyl)pyridin-3-yl)cyclopropyl)-1H-pyrrole-2-carboxamide)
 0.29 11.69 0.65 75-228 X-ray 1.75 monomer 1 x XCM, 1 x FMN, 1 x ORO HHblits 0.26
7kyk.2.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM589 (ethyl 3-methyl-4-((4-(trifluoromethyl)benzo[d]oxazol-7-yl)methyl)-1H-pyrrole-2-carboxylate)
 0.29 11.69 0.65 75-228 X-ray 2.15 monomer 1 x XAJ, 1 x FMN, 1 x ORO HHblits 0.26
7l0k.2.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM784 (3-(1-(3-methyl-4-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-pyrrole-2-carboxamido)ethyl)-1H-pyrazole-5-carboxamide)
 0.29 11.69 0.65 75-228 X-ray 1.96 monomer 1 x XE7, 1 x FMN, 1 x ORO HHblits 0.26
8eq0.1.A
Pyruvate kinase
Escherichia coli pyruvate kinase G381A
 0.26 11.76 0.64 76-232 X-ray 2.62 homo-tetramer 4 x GLY HHblits 0.26
6qxl.1.A
Pyruvate kinase
Crystal Structure of Pyruvate Kinase II (PykA) from Pseudomonas aeruginosa in complex with sodium malonate, magnesium and glucose-6-phosphate
 0.24 12.50 0.64 76-231 X-ray 2.43 homo-tetramer 4 x G6P, 4 x MG HHblits 0.26
6qxl.1.B
Pyruvate kinase
Crystal Structure of Pyruvate Kinase II (PykA) from Pseudomonas aeruginosa in complex with sodium malonate, magnesium and glucose-6-phosphate
 0.23 12.50 0.64 76-231 X-ray 2.43 homo-tetramer 4 x G6P, 4 x MG HHblits 0.26
6qxl.1.C
Pyruvate kinase
Crystal Structure of Pyruvate Kinase II (PykA) from Pseudomonas aeruginosa in complex with sodium malonate, magnesium and glucose-6-phosphate
 0.24 12.50 0.64 76-231 X-ray 2.43 homo-tetramer 4 x G6P, 4 x MG HHblits 0.26
6qxl.1.D
Pyruvate kinase
Crystal Structure of Pyruvate Kinase II (PykA) from Pseudomonas aeruginosa in complex with sodium malonate, magnesium and glucose-6-phosphate
 0.24 12.50 0.64 76-231 X-ray 2.43 homo-tetramer 4 x G6P, 4 x MG HHblits 0.26
8eq1.1.A
Pyruvate kinase
Escherichia coli pyruvate kinase D127N
 0.25 11.11 0.64 75-231 X-ray 2.32 homo-tetramer HHblits 0.26
8eds.1.A
Pyruvate kinase
Escherichia coli pyruvate kinase (PykF) P70Q
 0.26 11.11 0.64 75-231 X-ray 2.10 homo-tetramer HHblits 0.26
8edr.1.A
Pyruvate kinase
E. coli pyruvate kinase (PykF) P70Q
 0.26 11.11 0.64 75-231 X-ray 2.64 homo-tetramer HHblits 0.26
8eq3.1.A
Pyruvate kinase
Escherichia coli pyruvate kinase A301T
 0.26 10.46 0.64 75-231 X-ray 2.01 homo-tetramer 2 x IMD HHblits 0.25
8eq3.1.B
Pyruvate kinase
Escherichia coli pyruvate kinase A301T
 0.26 10.46 0.64 75-231 X-ray 2.01 homo-tetramer 2 x IMD HHblits 0.25
4yng.1.A
Pyruvate kinase I
Twinned pyruvate kinase from E. coli in the T-state
 0.27 11.84 0.64 76-231 X-ray 2.28 homo-tetramer HHblits 0.26
4yng.1.B
Pyruvate kinase I
Twinned pyruvate kinase from E. coli in the T-state
 0.27 11.84 0.64 76-231 X-ray 2.28 homo-tetramer HHblits 0.26
4yng.1.C
Pyruvate kinase I
Twinned pyruvate kinase from E. coli in the T-state
 0.27 11.84 0.64 76-231 X-ray 2.28 homo-tetramer HHblits 0.26
4yng.1.D
Pyruvate kinase I
Twinned pyruvate kinase from E. coli in the T-state
 0.27 11.84 0.64 76-231 X-ray 2.28 homo-tetramer HHblits 0.26
4yng.2.A
Pyruvate kinase I
Twinned pyruvate kinase from E. coli in the T-state
 0.26 11.84 0.64 76-231 X-ray 2.28 homo-tetramer HHblits 0.26
4yng.2.B
Pyruvate kinase I
Twinned pyruvate kinase from E. coli in the T-state
 0.26 11.84 0.64 76-231 X-ray 2.28 homo-tetramer HHblits 0.26
4yng.2.C
Pyruvate kinase I
Twinned pyruvate kinase from E. coli in the T-state
 0.27 11.84 0.64 76-231 X-ray 2.28 homo-tetramer HHblits 0.26
4yng.2.D
Pyruvate kinase I
Twinned pyruvate kinase from E. coli in the T-state
 0.27 11.84 0.64 76-231 X-ray 2.28 homo-tetramer HHblits 0.26
1e0u.1.A
Pyruvate kinase
Structure R271L mutant of E. coli pyruvate kinase
 0.26 11.18 0.64 76-231 X-ray 2.80 homo-tetramer HHblits 0.26
1e0u.1.C
Pyruvate kinase
Structure R271L mutant of E. coli pyruvate kinase
 0.27 11.18 0.64 76-231 X-ray 2.80 homo-tetramer HHblits 0.26
8edt.1.A
Pyruvate kinase
E. coli Pyruvate kinase (PykF) T462I
 0.26 11.18 0.64 76-231 X-ray 2.09 homo-tetramer HHblits 0.26
6wp3.1.A
Pyruvate kinase PKM
Pyruvate Kinase M2 Mutant-K433Q
 0.22 11.76 0.64 76-231 X-ray 1.84 homo-tetramer 4 x OXL, 4 x MG, 2 x K HHblits 0.25
3t05.1.A
Pyruvate kinase
Crystal structure of S. aureus Pyruvate Kinase
 0.26 11.26 0.63 77-231 X-ray 3.05 homo-tetramer HHblits 0.26
8edq.1.A
Pyruvate kinase
E. coli pyruvate kinase (PykF) I264F
 0.28 11.18 0.64 76-231 X-ray 2.88 homo-tetramer 2 x B3P HHblits 0.26
4krz.1.D
Pyruvate kinase
Apo crystal structure of pyruvate kinase (PYK) from Trypanosoma cruzi
 0.21 11.92 0.63 77-230 X-ray 2.50 homo-tetramer 4 x K HHblits 0.26
4krz.1.A
Pyruvate kinase
Apo crystal structure of pyruvate kinase (PYK) from Trypanosoma cruzi
 0.21 11.92 0.63 77-230 X-ray 2.50 homo-tetramer 4 x K HHblits 0.26
4ks0.1.B
Pyruvate kinase
Pyruvate kinase (PYK) from Trypanosoma cruzi in the presence of Magnesium, oxalate and F26BP
 0.21 11.92 0.63 77-230 X-ray 2.80 homo-tetramer 4 x MG, 4 x K, 4 x OXL, 4 x FDP HHblits 0.26
4ks0.1.C
Pyruvate kinase
Pyruvate kinase (PYK) from Trypanosoma cruzi in the presence of Magnesium, oxalate and F26BP
 0.21 11.92 0.63 77-230 X-ray 2.80 homo-tetramer 4 x MG, 4 x K, 4 x OXL, 4 x FDP HHblits 0.26
1e0t.1.A
Pyruvate kinase
R292D mutant of E. coli pyruvate kinase
 0.27 11.18 0.64 76-231 X-ray 1.80 homo-tetramer HHblits 0.25
8eu4.1.B
Pyruvate kinase
Escherichia coli pyruvate kinase A301S
 0.26 10.53 0.64 76-231 X-ray 2.10 homo-tetramer HHblits 0.25
8eu4.1.A
Pyruvate kinase
Escherichia coli pyruvate kinase A301S
 0.25 10.53 0.64 76-231 X-ray 2.10 homo-tetramer HHblits 0.25
8eu4.1.C
Pyruvate kinase
Escherichia coli pyruvate kinase A301S
 0.26 10.53 0.64 76-231 X-ray 2.10 homo-tetramer HHblits 0.25
8eu4.2.C
Pyruvate kinase
Escherichia coli pyruvate kinase A301S
 0.26 10.53 0.64 76-231 X-ray 2.10 homo-tetramer HHblits 0.25
8iw2.1.A
Pyruvate kinase
Entamoeba histolytica Pyruvate kinase
 0.26 14.77 0.63 76-230 X-ray 1.75 homo-dimer HHblits 0.27
6du6.1.A
Pyruvate kinase
Crystal structure of the pyruvate kinase (PK1) from the mosquito Aedes aegypti
 0.22 10.46 0.64 76-231 X-ray 3.51 homo-tetramer 4 x FBP HHblits 0.25
6du6.1.B
Pyruvate kinase
Crystal structure of the pyruvate kinase (PK1) from the mosquito Aedes aegypti
 0.22 10.46 0.64 76-231 X-ray 3.51 homo-tetramer 4 x FBP HHblits 0.25
6du6.1.C
Pyruvate kinase
Crystal structure of the pyruvate kinase (PK1) from the mosquito Aedes aegypti
 0.23 10.46 0.64 76-231 X-ray 3.51 homo-tetramer 4 x FBP HHblits 0.25
6du6.1.D
Pyruvate kinase
Crystal structure of the pyruvate kinase (PK1) from the mosquito Aedes aegypti
 0.22 10.46 0.64 76-231 X-ray 3.51 homo-tetramer 4 x FBP HHblits 0.25
4ip7.1.A
Pyruvate kinase isozymes L
Structure of the S12D variant of human liver pyruvate kinase in complex with citrate and FBP.
 0.24 11.76 0.64 75-231 X-ray 1.80 homo-tetramer 4 x MN, 4 x FLC, 4 x FBP, 1 x ADN HHblits 0.25
6jfb.1.A
Pyruvate kinase PKM Isoform M2
Crystal structure of human pyruvate kinase M2 isoform
 0.23 11.84 0.64 77-231 X-ray 2.12 homo-tetramer 4 x SER HHblits 0.25
6jfb.1.B
Pyruvate kinase PKM Isoform M2
Crystal structure of human pyruvate kinase M2 isoform
 0.22 11.84 0.64 77-231 X-ray 2.12 homo-tetramer 4 x SER HHblits 0.25
6jfb.1.D
Pyruvate kinase PKM Isoform M2
Crystal structure of human pyruvate kinase M2 isoform
 0.22 11.84 0.64 77-231 X-ray 2.12 homo-tetramer 4 x SER HHblits 0.25
8tbs.1.B
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator AG-946
 0.24 11.76 0.64 75-231 X-ray 2.35 homo-tetramer 4 x FBP, 4 x MN, 3 x K, 4 x PYR, 2 x HVI HHblits 0.25
8tbs.1.A
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator AG-946
 0.26 11.76 0.64 75-231 X-ray 2.35 homo-tetramer 4 x FBP, 4 x MN, 3 x K, 4 x PYR, 2 x HVI HHblits 0.25
8tbs.1.D
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator AG-946
 0.25 11.76 0.64 75-231 X-ray 2.35 homo-tetramer 4 x FBP, 4 x MN, 3 x K, 4 x PYR, 2 x HVI HHblits 0.25
8tbs.2.A
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator AG-946
 0.25 11.76 0.64 75-231 X-ray 2.35 homo-tetramer 4 x FBP, 4 x MN, 3 x K, 4 x PYR, 2 x HVI HHblits 0.25
8tbs.2.B
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator AG-946
 0.25 11.76 0.64 75-231 X-ray 2.35 homo-tetramer 4 x FBP, 4 x MN, 3 x K, 4 x PYR, 2 x HVI HHblits 0.25
8tbs.2.C
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator AG-946
 0.25 11.76 0.64 75-231 X-ray 2.35 homo-tetramer 4 x FBP, 4 x MN, 3 x K, 4 x PYR, 2 x HVI HHblits 0.25
8tbt.1.A
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator Compound 2
 0.25 11.76 0.64 75-231 X-ray 2.34 homo-tetramer 4 x FBP, 4 x PYR, 4 x MN, 4 x K, 2 x I07 HHblits 0.25
8tbt.1.B
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator Compound 2
 0.25 11.76 0.64 75-231 X-ray 2.34 homo-tetramer 4 x FBP, 4 x PYR, 4 x MN, 4 x K, 2 x I07 HHblits 0.25
8tbt.1.C
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator Compound 2
 0.24 11.76 0.64 75-231 X-ray 2.34 homo-tetramer 4 x FBP, 4 x PYR, 4 x MN, 4 x K, 2 x I07 HHblits 0.25
8tbt.1.D
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator Compound 2
 0.24 11.76 0.64 75-231 X-ray 2.34 homo-tetramer 4 x FBP, 4 x PYR, 4 x MN, 4 x K, 2 x I07 HHblits 0.25
8tbu.1.A
Pyruvate kinase PKLR
Structure of human erythrocyte pyruvate kinase in complex with an allosteric activator Compound 12
 0.25 11.76 0.64 75-231 X-ray 2.35 homo-tetramer 2 x I0R, 3 x PYR, 4 x FBP, 4 x MN, 2 x K HHblits 0.25
4ima.1.B
Pyruvate kinase
The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP
 0.25 11.76 0.64 75-231 X-ray 1.95 homo-tetramer 4 x MN, 4 x FLC, 4 x FBP, 1 x ADN HHblits 0.25
4ima.1.A
Pyruvate kinase
The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP
 0.25 11.76 0.64 75-231 X-ray 1.95 homo-tetramer 4 x MN, 4 x FLC, 4 x FBP, 1 x ADN HHblits 0.25
1pky.1.A
PYRUVATE KINASE
PYRUVATE KINASE FROM E. COLI IN THE T-STATE
 0.26 11.26 0.63 77-231 X-ray 2.50 homo-tetramer HHblits 0.26
6ech.1.A
Pyruvate kinase PKLR
Pyruvate Kinase Isoform L-type with phosphorylated Ser12 (pS12) in complex with FBP
 0.25 11.11 0.64 75-231 X-ray 2.19 homo-tetramer 4 x FBP, 12 x MG, 3 x ATP, 4 x OXL HHblits 0.25
6ech.1.C
Pyruvate kinase PKLR
Pyruvate Kinase Isoform L-type with phosphorylated Ser12 (pS12) in complex with FBP
 0.26 11.11 0.64 75-231 X-ray 2.19 homo-tetramer 4 x FBP, 12 x MG, 3 x ATP, 4 x OXL HHblits 0.25
6eck.1.A
Pyruvate kinase PKLR
Pyruvate Kinase Isoform L-type with phosphorylated Ser113 (pS113) in complex with FBP
 0.25 11.11 0.64 75-231 X-ray 2.36 homo-tetramer 4 x FBP, 2 x FLC HHblits 0.25
6eck.1.B
Pyruvate kinase PKLR
Pyruvate Kinase Isoform L-type with phosphorylated Ser113 (pS113) in complex with FBP
 0.26 11.11 0.64 75-231 X-ray 2.36 homo-tetramer 4 x FBP, 2 x FLC HHblits 0.25
6nn8.1.A
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-S531E
 0.25 11.76 0.64 75-231 X-ray 2.42 homo-tetramer HHblits 0.25
6nn8.1.B
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-S531E
 0.25 11.76 0.64 75-231 X-ray 2.42 homo-tetramer HHblits 0.25
6nn8.1.C
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-S531E
 0.27 11.76 0.64 75-231 X-ray 2.42 homo-tetramer HHblits 0.25
6nn8.1.D
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-S531E
 0.26 11.76 0.64 75-231 X-ray 2.42 homo-tetramer HHblits 0.25
6nn8.2.A
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-S531E
 0.26 11.76 0.64 75-231 X-ray 2.42 homo-tetramer HHblits 0.25
6nn8.2.B
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-S531E
 0.25 11.76 0.64 75-231 X-ray 2.42 homo-tetramer HHblits 0.25
6nn8.2.C
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-S531E
 0.26 11.76 0.64 75-231 X-ray 2.42 homo-tetramer HHblits 0.25
6nn8.2.D
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-S531E
 0.24 11.76 0.64 75-231 X-ray 2.42 homo-tetramer HHblits 0.25
4fxj.1.A
Pyruvate kinase isozymes M1/M2
Structure of M2 pyruvate kinase in complex with phenylalanine
 0.24 11.84 0.64 77-232 X-ray 2.90 homo-tetramer 4 x PHE HHblits 0.25
4fxf.1.B
Pyruvate kinase isozymes M1/M2
Structure of M2 pyruvate kinase in complex with phenylalanine
 0.24 11.84 0.64 77-232 X-ray 2.55 homo-tetramer 4 x OXL, 4 x K, 6 x MG, 4 x FBP, 2 x ATP HHblits 0.25
4fxf.1.A
Pyruvate kinase isozymes M1/M2
Structure of M2 pyruvate kinase in complex with phenylalanine
 0.24 11.84 0.64 77-232 X-ray 2.55 homo-tetramer 4 x OXL, 4 x K, 6 x MG, 4 x FBP, 2 x ATP HHblits 0.25
4fxj.1.D
Pyruvate kinase isozymes M1/M2
Structure of M2 pyruvate kinase in complex with phenylalanine
 0.24 11.84 0.64 77-232 X-ray 2.90 homo-tetramer 4 x PHE HHblits 0.25
6nn4.1.A
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-D499N, in complex with Fru-1,6-BP
 0.24 11.76 0.64 75-231 X-ray 2.15 homo-tetramer 4 x FBP HHblits 0.24
8iau.1.A
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate
 0.24 9.21 0.64 75-230 X-ray 2.00 homo-tetramer 4 x FBP, 4 x MG, 4 x OXL, 4 x K HHblits 0.25
8ias.1.B
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase
 0.24 9.21 0.64 75-230 X-ray 2.00 homo-tetramer HHblits 0.25
8ias.1.D
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase
 0.24 9.21 0.64 75-230 X-ray 2.00 homo-tetramer HHblits 0.25
8iat.1.A
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate
 0.24 9.21 0.64 75-230 X-ray 1.80 homo-tetramer 8 x OXL, 4 x MG, 4 x K HHblits 0.25
8iat.1.B
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate
 0.24 9.21 0.64 75-230 X-ray 1.80 homo-tetramer 8 x OXL, 4 x MG, 4 x K HHblits 0.25
8iat.1.D
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate
 0.24 9.21 0.64 75-230 X-ray 1.80 homo-tetramer 8 x OXL, 4 x MG, 4 x K HHblits 0.25
8ias.1.A
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase
 0.24 9.21 0.64 75-230 X-ray 2.00 homo-tetramer HHblits 0.25
8iau.1.C
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate
 0.24 9.21 0.64 75-230 X-ray 2.00 homo-tetramer 4 x FBP, 4 x MG, 4 x OXL, 4 x K HHblits 0.25
8iau.2.C
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate
 0.24 9.21 0.64 75-230 X-ray 2.00 homo-tetramer 4 x FBP, 3 x MG, 3 x OXL, 3 x K HHblits 0.25
8iav.1.A
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with fructose 1,6-bisphosphate
 0.24 9.21 0.64 75-230 X-ray 2.59 homo-tetramer 4 x FBP HHblits 0.25
8iav.1.C
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with fructose 1,6-bisphosphate
 0.24 9.21 0.64 75-230 X-ray 2.59 homo-tetramer 4 x FBP HHblits 0.25
8iaw.1.A
Pyruvate kinase
Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with phosphoenolpyruvate
 0.24 9.21 0.64 75-230 X-ray 2.89 homo-tetramer 4 x MG HHblits 0.25
5x0i.1.A
Pyruvate kinase PKM
Crystal structure of PKM2 R399E mutant complexed with FBP and serine
 0.24 11.84 0.64 77-232 X-ray 2.64 homo-tetramer 4 x FBP, 4 x SER, 4 x PYR, 4 x MG, 4 x K HHblits 0.25
8hgf.1.A
Pyruvate kinase PKM
Human PKM2 mutant - C326S
 0.26 11.84 0.64 76-231 X-ray 3.10 homo-tetramer HHblits 0.25
8hgf.1.B
Pyruvate kinase PKM
Human PKM2 mutant - C326S
 0.25 11.84 0.64 76-231 X-ray 3.10 homo-tetramer HHblits 0.25
8hgf.2.A
Pyruvate kinase PKM
Human PKM2 mutant - C326S
 0.26 11.84 0.64 76-231 X-ray 3.10 homo-tetramer HHblits 0.25
8hgf.2.B
Pyruvate kinase PKM
Human PKM2 mutant - C326S
 0.26 11.84 0.64 76-231 X-ray 3.10 homo-tetramer HHblits 0.25
6wp4.1.A
Pyruvate kinase PKM
Pyruvate Kinase M2 mutant-S37E
 0.23 11.84 0.64 76-231 X-ray 1.90 homo-tetramer 4 x MG, 5 x K, 2 x OXL HHblits 0.25
6wp5.1.A
Pyruvate kinase PKM
Pyruvate Kinase M2 mutant-S37D
 0.25 11.84 0.64 76-231 X-ray 2.17 homo-tetramer 4 x K, 3 x MG, 4 x OXL, 3 x FBP HHblits 0.25
5ocw.1.A
Tryptophan synthase alpha chain
Structure of Mycobacterium tuberculosis tryptophan synthase in space group F222
 0.32 12.08 0.63 78-228 X-ray 4.00 hetero-2-2-mer 2 x P1T HHblits 0.26
4kct.1.C
Pyruvate kinase 1
Pyruvate kinase (PYK) from Trypanosoma brucei soaked with Oxaloacetate
 0.24 12.00 0.63 77-230 X-ray 1.95 homo-tetramer 4 x MG, 4 x K, 4 x PYR, 4 x FDP HHblits 0.26
4kct.1.B
Pyruvate kinase 1
Pyruvate kinase (PYK) from Trypanosoma brucei soaked with Oxaloacetate
 0.23 12.00 0.63 77-230 X-ray 1.95 homo-tetramer 4 x MG, 4 x K, 4 x PYR, 4 x FDP HHblits 0.26
3qv9.1.A
Pyruvate kinase 2
Crystal structure of Trypanosoma cruzi pyruvate kinase(TcPYK)in complex with ponceau S.
 0.24 12.00 0.63 77-230 X-ray 2.10 homo-tetramer 4 x K, 2 x QV7 HHblits 0.26
6ttf.1.C
Pyruvate kinase PKM
PKM2 in complex with Compound 5
 0.25 11.92 0.63 77-231 EM 0.00 homo-tetramer 4 x FBP HHblits 0.25
6ttq.1.B
Pyruvate kinase PKM
PKM2 in complex with Compound 10
 0.24 11.92 0.63 77-231 EM 2.70 homo-tetramer 4 x NXH, 4 x FBP HHblits 0.25
6tth.1.C
Pyruvate kinase PKM
PKM2 in complex with L-threonine
 0.25 11.92 0.63 77-231 EM 0.00 homo-tetramer 4 x FBP, 4 x THR HHblits 0.25
1zjh.1.C
Pyruvate kinase, isozymes M1/M2
Structure of human muscle pyruvate kinase (PKM2)
 0.25 11.92 0.63 77-231 X-ray 2.20 homo-tetramer HHblits 0.25
4b2d.1.D
PYRUVATE KINASE ISOZYMES M1/M2
human PKM2 with L-serine and FBP bound.
 0.24 11.92 0.63 77-231 X-ray 2.30 hetero-3-1-mer 4 x SER, 4 x FBP, 2 x MG HHblits 0.25
1vcf.2.B
isopentenyl-diphosphate delta-isomerase
Crystal Structure of IPP isomerase at I422
 0.29 19.18 0.61 85-231 X-ray 2.60 homo-tetramer 4 x CD, 4 x FMN HHblits 0.28
1vcg.2.B
isopentenyl-diphosphate delta-isomerase
Crystal Structure of IPP isomerase at P43212
 0.29 19.18 0.61 85-231 X-ray 3.02 homo-tetramer 4 x FMN HHblits 0.28
3dh7.1.A
Isopentenyl-diphosphate delta-isomerase
Structure of T. thermophilus IDI-2 in complex with PPi
 0.29 19.18 0.61 85-231 X-ray 2.97 homo-tetramer 4 x FMN, 2 x POP HHblits 0.28
3srk.1.A
Pyruvate kinase
A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase
 0.23 12.00 0.63 77-230 X-ray 2.65 homo-tetramer 4 x LSA, 8 x K, 2 x PTK HHblits 0.26
1pkl.2.C
PROTEIN (PYRUVATE KINASE)
THE STRUCTURE OF LEISHMANIA PYRUVATE KINASE
 0.24 12.00 0.63 77-230 X-ray 2.35 homo-tetramer HHblits 0.26
1pkl.1.C
PROTEIN (PYRUVATE KINASE)
THE STRUCTURE OF LEISHMANIA PYRUVATE KINASE
 0.24 12.00 0.63 77-230 X-ray 2.35 homo-tetramer HHblits 0.26
3qv6.1.A
Pyruvate kinase
Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with acid blue 80.
 0.24 12.00 0.63 77-230 X-ray 2.85 homo-tetramer 2 x QV6, 8 x K HHblits 0.26
3hqq.6.C
Pyruvate kinase
Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK) in complex with Fructose 2,6 bisphosphate
 0.25 12.00 0.63 77-230 X-ray 5.07 homo-tetramer 4 x FDP HHblits 0.26
3hqp.2.A
Pyruvate kinase
Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK) in complex with ATP, Oxalate and fructose 2,6 bisphosphate
 0.24 12.00 0.63 77-230 X-ray 2.30 monomer 1 x MG, 2 x K, 1 x OXL, 1 x FDP, 1 x ATP HHblits 0.26
3hqo.3.A
Pyruvate kinase
Crystal structures of Leishmania mexicana pyruvate kinase (LmPYK) in complex with ATP and Oxalate
 0.23 12.00 0.63 77-230 X-ray 3.40 homo-dimer 2 x MG, 2 x K, 2 x OXL, 2 x ATP HHblits 0.26
6gg3.1.D
Pyruvate kinase PKM
Crystal structure of M2 PYK in complex with Alanine.
 0.24 11.92 0.63 77-231 X-ray 3.72 homo-tetramer 3 x ALA HHblits 0.25
6gg6.2.A
Pyruvate kinase PKM
Crystal structure of M2 PYK in complex with Serine.
 0.25 11.92 0.63 77-231 X-ray 2.96 homo-tetramer 4 x K, 4 x MG, 4 x SER HHblits 0.25
6nu1.2.A
Pyruvate kinase PKM
Crystal Structure of Human PKM2 in Complex with L-cysteine
 0.24 11.92 0.63 77-231 X-ray 2.25 homo-dimer 2 x CYS, 2 x FBP, 2 x MG, 2 x OXL, 1 x K HHblits 0.25
6nu1.1.B
Pyruvate kinase PKM
Crystal Structure of Human PKM2 in Complex with L-cysteine
 0.24 11.92 0.63 77-231 X-ray 2.25 homo-tetramer 4 x CYS, 4 x FBP, 4 x MG, 4 x OXL, 2 x K HHblits 0.25
6nu1.1.D
Pyruvate kinase PKM
Crystal Structure of Human PKM2 in Complex with L-cysteine
 0.25 11.92 0.63 77-231 X-ray 2.25 homo-tetramer 4 x CYS, 4 x FBP, 4 x MG, 4 x OXL, 2 x K HHblits 0.25
6gg3.3.D
Pyruvate kinase PKM
Crystal structure of M2 PYK in complex with Alanine.
 0.24 11.92 0.63 77-231 X-ray 3.72 homo-tetramer 4 x ALA HHblits 0.25
6gg4.1.A
Pyruvate kinase PKM
Crystal structure of M2 PYK in complex with Phenyalanine.
 0.24 11.92 0.63 77-231 X-ray 2.46 homo-tetramer 4 x PHE, 4 x K HHblits 0.25
3srh.1.B
Pyruvate kinase isozymes M1/M2
Human M2 pyruvate kinase
 0.24 11.92 0.63 77-231 X-ray 2.60 homo-tetramer HHblits 0.25
3srh.1.C
Pyruvate kinase isozymes M1/M2
Human M2 pyruvate kinase
 0.24 11.92 0.63 77-231 X-ray 2.60 homo-tetramer HHblits 0.25
8hmq.1.C
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant P403A
 0.25 11.92 0.63 77-231 X-ray 2.50 homo-tetramer 4 x OXL, 9 x MG, 3 x FBP HHblits 0.25
8hmq.1.B
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant P403A
 0.24 11.92 0.63 77-231 X-ray 2.50 homo-tetramer 4 x OXL, 9 x MG, 3 x FBP HHblits 0.25
8hmq.1.A
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant P403A
 0.24 11.92 0.63 77-231 X-ray 2.50 homo-tetramer 4 x OXL, 9 x MG, 3 x FBP HHblits 0.25
8hmr.1.A
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant L144P
 0.25 11.92 0.63 77-231 X-ray 2.60 homo-tetramer 4 x OXL, 4 x FBP, 4 x MG HHblits 0.25
8hmr.1.B
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant L144P
 0.25 11.92 0.63 77-231 X-ray 2.60 homo-tetramer 4 x OXL, 4 x FBP, 4 x MG HHblits 0.25
4wj8.1.A
Pyruvate kinase PKM
Human Pyruvate Kinase M2 Mutant C424A
 0.25 11.92 0.63 77-231 X-ray 2.87 homo-tetramer 4 x OXD, 2 x FBP, 4 x K, 4 x MG HHblits 0.25
6hye.1.C
Pyridoxal 5'-phosphate synthase subunit PDX1.3
PDX1.2/PDX1.3 complex (PDX1.3:K97A)
 0.27 11.33 0.63 74-231 X-ray 2.53 hetero-12-12-mer HHblits 0.25
1pkm.1.A
M1 PYRUVATE KINASE
THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS
 0.27 11.92 0.63 77-231 X-ray 2.60 homo-tetramer HHblits 0.25
6nn7.1.A
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-GGG
 0.24 11.18 0.64 76-231 X-ray 2.32 homo-tetramer 2 x FLC HHblits 0.24
6nn7.1.B
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-GGG
 0.25 11.18 0.64 76-231 X-ray 2.32 homo-tetramer 2 x FLC HHblits 0.24
6nn7.1.C
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-GGG
 0.24 11.18 0.64 76-231 X-ray 2.32 homo-tetramer 2 x FLC HHblits 0.24
6nn7.1.D
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-GGG
 0.24 11.18 0.64 76-231 X-ray 2.32 homo-tetramer 2 x FLC HHblits 0.24
6nn7.2.A
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-GGG
 0.24 11.18 0.64 76-231 X-ray 2.32 homo-tetramer HHblits 0.24
6nn7.2.B
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-GGG
 0.25 11.18 0.64 76-231 X-ray 2.32 homo-tetramer HHblits 0.24
6nn7.2.C
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-GGG
 0.25 11.18 0.64 76-231 X-ray 2.32 homo-tetramer HHblits 0.24
6nn7.2.D
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-GGG
 0.25 11.18 0.64 76-231 X-ray 2.32 homo-tetramer HHblits 0.24
3qh2.2.A
Regulatory protein tenI
Crystal structure of TenI from Bacillus subtilis complexed with product cThz-P
 0.31 8.72 0.63 77-234 X-ray 2.23 homo-dimer 2 x 3NM HHblits 0.26
1yad.1.B
Regulatory protein tenI
Structure of TenI from Bacillus subtilis
 0.31 8.72 0.63 77-234 X-ray 2.10 homo-dimer 2 x 144 HHblits 0.26
6nn5.1.A
Pyruvate kinase PKLR
The structure of human liver pyruvate kinase, hLPYK-W527H
 0.26 11.18 0.64 76-231 X-ray 2.26 homo-tetramer HHblits 0.24
2vgf.1.A
PYRUVATE KINASE ISOZYMES R/L
HUMAN ERYTHROCYTE PYRUVATE KINASE: T384M mutant
 0.23 11.26 0.63 77-231 X-ray 2.75 homo-tetramer 4 x FBP, 4 x PGA, 4 x K, 4 x MN HHblits 0.25
2vgf.1.C
PYRUVATE KINASE ISOZYMES R/L
HUMAN ERYTHROCYTE PYRUVATE KINASE: T384M mutant
 0.23 11.26 0.63 77-231 X-ray 2.75 homo-tetramer 4 x FBP, 4 x PGA, 4 x K, 4 x MN HHblits 0.25
2vgb.1.A
PYRUVATE KINASE ISOZYMES R/L
HUMAN ERYTHROCYTE PYRUVATE KINASE
 0.22 11.26 0.63 77-231 X-ray 2.73 homo-tetramer 4 x FBP, 4 x PGA, 4 x K, 4 x MN HHblits 0.25
2vgi.1.A
PYRUVATE KINASE ISOZYMES R/L
HUMAN ERYTHROCYTE PYRUVATE KINASE: R486W MUTANT
 0.24 11.26 0.63 77-231 X-ray 2.87 homo-tetramer 4 x FBP, 4 x PGA, 4 x K, 4 x MN HHblits 0.24
2vgg.1.A
PYRUVATE KINASE ISOZYMES R/L
HUMAN ERYTHROCYTE PYRUVATE KINASE: R479H MUTANT
 0.23 11.26 0.63 77-231 X-ray 2.74 homo-tetramer 4 x FBP, 4 x PGA, 4 x K, 4 x MN HHblits 0.24
7m32.2.A
Dihydropyrimidine dehydrogenase [NADP(+)]
Dihydropyrimidine Dehydrogenase (DPD) C671A Mutant Soaked with Uracil and NADPH Anaerobically
 0.28 18.57 0.59 75-214 X-ray 1.82 homo-dimer 1 x PRO, 8 x SF4, 2 x FAD, 2 x URA, 2 x FNR, 1 x LEU, 1 x ALA HHblits 0.30
5zjb.1.A
Putative N-acetylmannosamine-6-phosphate 2-epimerase
Structure of N-acetylmannosamine-6-phosphate-2-epimerase from Vibrio cholerae
 0.31 16.78 0.60 80-231 X-ray 1.70 homo-dimer HHblits 0.28
4ori.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Rat dihydroorotate dehydrogenase bound with DSM338 (N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine)
 0.25 14.79 0.60 74-215 X-ray 1.50 monomer 1 x FMN, 1 x ORO, 1 x 2V6 HHblits 0.28
8f6n.2.B
Dihydropyrimidine dehydrogenase [NADP(+)]
Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Thymine Quasi-Anaerobically
 0.28 17.99 0.58 76-214 X-ray 2.12 homo-dimer 8 x SF4, 2 x FMN, 2 x FAD, 2 x TDR HHblits 0.30
7m31.2.A
Dihydropyrimidine dehydrogenase [NADP(+)]
Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Thymine and NADPH Anaerobically
 0.27 17.99 0.58 76-214 X-ray 1.69 homo-dimer 1 x PRO, 8 x SF4, 2 x FAD, 2 x NAP, 2 x TDR, 2 x FMN HHblits 0.30
7smj.1.A
AI-designed TIM-barrel F2N
F2N structure, protein design with deep learning
 0.29 21.58 0.58 74-231 X-ray 1.58 monomer HHblits 0.30
1wv2.1.A
Thiazole biosynthesis protein thiG
Crystal structure of thiamine biosynthesis protein from Pseudomonas Aeruginosa
 0.30 15.49 0.60 84-231 X-ray 2.90 homo-dimer HHblits 0.28
6uy4.1.A
Dihydroorotate dehydrogenase
Crystal structure of dihydroorotate dehydrogenase from Schistosoma mansoni
 0.26 17.02 0.59 75-215 X-ray 2.80 monomer 1 x QLA, 1 x FMN HHblits 0.28
5wsb.1.B
Pyruvate kinase
Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, allosteric activators AMP and Glucose 6-Phosphate
 0.25 11.81 0.61 83-230 X-ray 2.25 homo-tetramer 4 x AMP, 4 x G6P, 4 x MG, 4 x OXL, 1 x K HHblits 0.27
5ws9.1.C
Pyruvate kinase
Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, ATP and allosteric activator AMP
 0.26 11.81 0.61 83-230 X-ray 1.90 homo-tetramer 6 x MG, 4 x OXL, 4 x AMP, 3 x K, 4 x ATP HHblits 0.27
5wrp.1.D
Pyruvate kinase
T-state crystal structure of pyruvate kinase from Mycobacterium tuberculosis
 0.25 11.81 0.61 83-230 X-ray 2.85 homo-tetramer HHblits 0.27
5wrp.1.C
Pyruvate kinase
T-state crystal structure of pyruvate kinase from Mycobacterium tuberculosis
 0.25 11.81 0.61 83-230 X-ray 2.85 homo-tetramer HHblits 0.27
5dbt.1.A
Deoxyribose-phosphate aldolase
Crystal structure of C-terminal truncated 2-deoxyribose-5-phosphate aldolase (1-201) from Streptococcus suis
 0.22 12.59 0.60 80-226 X-ray 2.81 homo-dimer HHblits 0.27
1a3x.1.A
PYRUVATE KINASE
PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PG, MN2+ AND K+
 0.24 13.19 0.61 84-231 X-ray 3.00 homo-tetramer 4 x PGA, 4 x MN, 4 x K HHblits 0.26
1a3w.1.A
PYRUVATE KINASE
PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH FBP, PG, MN2+ AND K+
 0.26 13.19 0.61 84-231 X-ray 3.00 homo-tetramer 4 x PGA, 4 x FBP, 4 x MN, 4 x K HHblits 0.26
7ut5.1.A
Dihydroorotate dehydrogenase (quinone)
Acinetobacter baumannii dihydroorotate dehydrogenase bound with inhibitor DSM186
 0.26 12.77 0.59 75-215 X-ray 1.40 monomer 1 x OBR, 1 x FMN, 1 x ORO HHblits 0.28
7ut5.2.A
Dihydroorotate dehydrogenase (quinone)
Acinetobacter baumannii dihydroorotate dehydrogenase bound with inhibitor DSM186
 0.26 12.77 0.59 75-215 X-ray 1.40 monomer 1 x OBR, 1 x FMN, 1 x ORO HHblits 0.28
4oqv.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
High resolution crystal structure of human dihydroorotate dehydrogenase bound with DSM338 (N-[3,5-difluoro-4-(trifluoromethyl)phenyl]-5-methyl-2-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine)
 0.27 13.38 0.60 74-215 X-ray 1.23 monomer 1 x FMN, 1 x ORO, 1 x 2V6 HHblits 0.27
6qu7.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Crystal structure of human DHODH in complex with BAY 2402234
 0.27 13.38 0.60 74-215 X-ray 1.52 monomer 1 x ORO, 1 x FMN, 1 x JJE HHblits 0.27
8dhf.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
DHODH IN COMPLEX WITH LIGAND 11
 0.28 13.38 0.60 74-215 X-ray 1.78 monomer 1 x FMN, 1 x ORO, 1 x T6L HHblits 0.27
7k2u.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
DHODH IN COMPLEX WITH LIGAND 13
 0.27 13.38 0.60 74-215 X-ray 1.73 monomer 1 x FMN, 1 x ORO, 1 x VU7 HHblits 0.27
5ksw.1.A
Dihydroorotate dehydrogenase
DHODB-I74D mutant
 0.29 13.48 0.59 74-215 X-ray 2.47 hetero-2-2-mer 2 x FMN, 2 x FAD, 2 x FES HHblits 0.28
5ksw.2.B
Dihydroorotate dehydrogenase
DHODB-I74D mutant
 0.30 13.48 0.59 74-215 X-ray 2.47 hetero-2-2-mer 2 x FAD, 2 x FES, 2 x FMN HHblits 0.28
5h91.1.A
Deoxyribose-phosphate aldolase
LbDERA mutant-T29L/F163Y
 0.25 14.18 0.59 83-227 X-ray 1.77 homo-dimer HHblits 0.27
4my9.1.A
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor C91
 0.27 17.99 0.58 74-214 X-ray 2.59 homo-tetramer 4 x IMP, 4 x C91 HHblits 0.29
4my1.1.B
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Bacillus anthracis str. Ames complexed with P68
 0.27 17.99 0.58 74-214 X-ray 2.60 homo-tetramer 4 x IMP, 4 x P68 HHblits 0.29
4my9.1.B
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor C91
 0.27 17.99 0.58 74-214 X-ray 2.59 homo-tetramer 4 x IMP, 4 x C91 HHblits 0.29
4my8.2.D
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor Q21
 0.26 17.99 0.58 74-214 X-ray 2.29 homo-tetramer 4 x IMP, 4 x Q21 HHblits 0.29
4myx.2.C
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Bacillus anthracis str. Ame complexed with P32
 0.27 17.99 0.58 74-214 X-ray 2.70 homo-tetramer 4 x IMP, 4 x 2F0 HHblits 0.29
5urs.2.B
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P178
 0.27 17.99 0.58 74-214 X-ray 2.39 homo-tetramer 4 x IMP, 4 x 8LA, 4 x K HHblits 0.29
7mtu.1.C
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus anthracis in the complex with IMP and the inhibitor P221
 0.27 17.99 0.58 74-214 X-ray 2.34 homo-tetramer 4 x IMP, 4 x ZO7, 4 x K HHblits 0.29
5uwx.1.B
Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P176
 0.27 19.86 0.59 74-215 X-ray 1.85 homo-tetramer 4 x 8L7, 4 x IMP HHblits 0.27
5uzs.1.C
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200
 0.27 19.86 0.59 74-215 X-ray 2.37 homo-tetramer 4 x IMP, 4 x 8L4, 1 x MG, 2 x K HHblits 0.27
5uwx.1.A
Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P176
 0.27 19.86 0.59 74-215 X-ray 1.85 homo-tetramer 4 x 8L7, 4 x IMP HHblits 0.27
5uzs.1.B
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P200
 0.27 19.86 0.59 74-215 X-ray 2.37 homo-tetramer 4 x IMP, 4 x 8L4, 1 x MG, 2 x K HHblits 0.27
5uzc.1.A
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P221
 0.27 19.86 0.59 74-215 X-ray 1.85 homo-tetramer 4 x IMP, 4 x 8N1 HHblits 0.27
5vsv.1.C
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225
 0.27 19.86 0.59 74-215 X-ray 2.21 homo-tetramer 4 x IMP, 4 x 8KY HHblits 0.27
5uze.1.D
Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P182
 0.27 19.86 0.59 74-215 X-ray 2.27 homo-tetramer 4 x IMP, 4 x 8L1, 2 x K HHblits 0.27
5uze.1.A
Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P182
 0.27 19.86 0.59 74-215 X-ray 2.27 homo-tetramer 4 x IMP, 4 x 8L1, 2 x K HHblits 0.27
6cjf.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Human dihydroorotate dehydrogenase bound to 4-quinoline carboxylic acid inhibitor 43
 0.28 13.48 0.59 74-214 X-ray 1.63 monomer 1 x FMN, 1 x ORO, 1 x F54, 1 x ZWI HHblits 0.27
6cjg.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
Human dihydroorotate dehydrogenase bound to napthyridine inhibitor 46
 0.28 13.48 0.59 74-214 X-ray 2.85 monomer 1 x FMN, 1 x ORO, 1 x F51, 1 x ZWI HHblits 0.27
4igh.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
High resolution crystal structure of human dihydroorotate dehydrogenase bound with 4-quinoline carboxylic acid analog
 0.28 13.48 0.59 74-214 X-ray 1.30 monomer 1 x FMN, 1 x ORO, 1 x 1EA, 1 x ZWI HHblits 0.27
6nub.1.A
Pyruvate kinase PKM
Pyruvate Kinase M2 Mutant - S437Y in Complex with L-serine
 0.23 11.72 0.61 84-231 X-ray 1.70 homo-dimer 2 x SER, 2 x MG, 2 x OXL, 2 x K, 2 x B3P HHblits 0.25
6nub.1.B
Pyruvate kinase PKM
Pyruvate Kinase M2 Mutant - S437Y in Complex with L-serine
 0.24 11.72 0.61 84-231 X-ray 1.70 homo-dimer 2 x SER, 2 x MG, 2 x OXL, 2 x K, 2 x B3P HHblits 0.25
3zws.1.A
DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL
Structure of Human Dihydroorotate Dehydrogenase with a Bound Inhibitor
 0.26 13.48 0.59 74-214 X-ray 1.60 monomer 1 x FMN, 1 x ORO, 1 x AVQ HHblits 0.27
6et4.1.A
Dihydroorotate dehydrogenase (quinone), mitochondrial
HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH NOVEL INHIBITOR
 0.26 13.48 0.59 74-214 X-ray 1.70 monomer 1 x FMN, 1 x DOR, 1 x SDV, 1 x DDQ HHblits 0.27
7oo1.1.A
Pyruvate kinase
Structure, function and characterization of a second pyruvate kinase isozyme in Pseudomonas aeruginosa.
 0.26 14.29 0.59 87-231 X-ray 3.01 monomer HHblits 0.28
7oo1.2.A
Pyruvate kinase
Structure, function and characterization of a second pyruvate kinase isozyme in Pseudomonas aeruginosa.
 0.27 14.29 0.59 87-231 X-ray 3.01 monomer HHblits 0.28
1f76.1.A
Dihydroorotate dehydrogenase (quinone)
ESCHERICHIA COLI DIHYDROOROTATE DEHYDROGENASE
 0.27 17.39 0.58 75-212 X-ray 2.50 monomer 1 x FMN, 2 x ORO HHblits 0.29
2b4g.1.A
dihydroorotate dehydrogenase
dihydroorotate dehydrogenase
 0.26 15.71 0.59 74-213 X-ray 1.95 homo-dimer 6 x BR, 2 x FMN, 2 x ORO HHblits 0.28
3gk0.1.A
Pyridoxine 5'-phosphate synthase
Crystal structure of pyridoxal phosphate biosynthetic protein from Burkholderia pseudomallei
 0.29 13.38 0.60 87-233 X-ray 2.28 homo-tetramer 2 x DXP HHblits 0.27
1pii.1.A
N-(5'PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE
THREE-DIMENSIONAL STRUCTURE OF THE BIFUNCTIONAL ENZYME PHOSPHORIBOSYLANTHRANILATE ISOMERASE: INDOLEGLYCEROLPHOSPHATE SYNTHASE FROM ESCHERICHIA COLI REFINED AT 2.0 ANGSTROMS RESOLUTION
 0.31 10.49 0.60 74-225 X-ray 2.00 monomer HHblits 0.26
3pp7.1.A
Pyruvate kinase
Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis.
 0.24 11.89 0.60 84-230 X-ray 2.35 homo-tetramer 2 x PTK, 8 x K, 2 x SVR HHblits 0.26
4qm1.1.B
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase with an Internal Deletion of the CBS Domain from Bacillus anthracis str. Ames complexed with inhibitor D67
 0.27 18.12 0.58 75-214 X-ray 2.80 homo-tetramer 4 x IMP, 4 x 39H HHblits 0.29
5xfv.1.A
Dihydroorotate dehydrogenase (fumarate)
Crystal structures of FMN-bound form of dihydroorotate dehydrogenase from Trypanosoma brucei
 0.26 15.71 0.59 74-213 X-ray 1.79 homo-dimer 2 x FMN HHblits 0.28
3qtg.1.A
Pyruvate kinase
Crystal structure of pyruvate kinase from Pyrobaculum aerophilum
 0.24 15.00 0.59 88-231 X-ray 2.20 homo-tetramer HHblits 0.28
3qtg.1.B
Pyruvate kinase
Crystal structure of pyruvate kinase from Pyrobaculum aerophilum
 0.23 15.00 0.59 88-231 X-ray 2.20 homo-tetramer HHblits 0.28
1mzh.1.A
Deoxyribose-phosphate aldolase
QR15, an Aldolase
 0.19 15.60 0.59 84-227 X-ray 2.00 homo-dimer HHblits 0.27
1mzh.1.B
Deoxyribose-phosphate aldolase
QR15, an Aldolase
 0.19 15.60 0.59 84-227 X-ray 2.00 homo-dimer HHblits 0.27
7ueh.1.A
Pyruvate kinase
Pyruvate kinase from Zymomonas mobilis
 0.27 16.67 0.58 87-229 X-ray 2.40 homo-dimer HHblits 0.29
7ueh.2.A
Pyruvate kinase
Pyruvate kinase from Zymomonas mobilis
 0.26 16.67 0.58 87-229 X-ray 2.40 homo-dimer HHblits 0.29
7ueh.2.B
Pyruvate kinase
Pyruvate kinase from Zymomonas mobilis
 0.27 16.67 0.58 87-229 X-ray 2.40 homo-dimer HHblits 0.29
7ueh.3.A
Pyruvate kinase
Pyruvate kinase from Zymomonas mobilis
 0.27 16.67 0.58 87-229 X-ray 2.40 homo-dimer HHblits 0.29
7ueh.3.B
Pyruvate kinase
Pyruvate kinase from Zymomonas mobilis
 0.27 16.67 0.58 87-229 X-ray 2.40 homo-dimer HHblits 0.29
7ueh.4.A
Pyruvate kinase
Pyruvate kinase from Zymomonas mobilis
 0.27 16.67 0.58 87-229 X-ray 2.40 homo-dimer HHblits 0.29
7ueh.4.B
Pyruvate kinase
Pyruvate kinase from Zymomonas mobilis
 0.26 16.67 0.58 87-229 X-ray 2.40 homo-dimer HHblits 0.29
1m6j.1.A
Triosephosphate Isomerase
CRYSTAL STRUCTURE OF TRIOSEPHOSPHATE ISOMERASE FROM ENTAMOEBA HISTOLYTICA
 0.21 20.00 0.57 91-225 X-ray 1.50 homo-dimer HHblits 0.30
1vqt.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of Orotidine 5'-phosphate decarboxylase (TM0332) from Thermotoga maritima at 2.00 A resolution
 0.22 16.55 0.58 74-226 X-ray 2.00 homo-dimer HHblits 0.28
6mgu.1.A
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Bacillus Anthracis in the complex with inhibitor Oxanosine monophosphate
 0.24 16.55 0.58 74-214 X-ray 1.54 homo-tetramer 4 x JQS, 4 x K HHblits 0.28
8p4q.1.A
IMP dehydrogenase subunit
Structure of the IMP dehydrogenase related protein GUAB3 from Synechocystis PCC 6803
 0.27 20.74 0.57 78-215 X-ray 1.88 homo-tetramer 4 x IMP, 4 x XMP HHblits 0.30
5zjp.1.A
Putative N-acetylmannosamine-6-phosphate 2-epimerase
Structure of N-acetylmannosamine-6-phosphate-2-epimerase from Vibrio cholerae with N-acetylglucosamine-6-phosphate
 0.30 15.00 0.59 81-229 X-ray 2.66 homo-dimer 2 x RFW HHblits 0.27
5dlc.1.A
Pyridoxine 5'-phosphate synthase
X-ray Crystal Structure of a Pyridoxine 5-prime-phosphate synthase from Pseudomonas aeruginosa
 0.29 14.18 0.59 87-232 X-ray 2.65 homo-dimer HHblits 0.26
6rg0.1.A
Pyridoxine 5'-phosphate synthase
Structure of pdxj
 0.27 12.06 0.59 87-232 X-ray 3.07 monomer HHblits 0.26
6rg0.2.A
Pyridoxine 5'-phosphate synthase
Structure of pdxj
 0.27 12.06 0.59 87-232 X-ray 3.07 monomer HHblits 0.26
6rg0.3.A
Pyridoxine 5'-phosphate synthase
Structure of pdxj
 0.27 12.06 0.59 87-232 X-ray 3.07 monomer HHblits 0.26
6rg0.4.A
Pyridoxine 5'-phosphate synthase
Structure of pdxj
 0.27 12.06 0.59 87-232 X-ray 3.07 monomer HHblits 0.26
1w0m.1.A
TRIOSEPHOSPHATE ISOMERASE
Triosephosphate isomerase from Thermoproteus tenax
 0.29 18.80 0.56 90-227 X-ray 2.50 homo-tetramer HHblits 0.31
3w72.1.A
Dihydroorotate dehydrogenase (fumarate)
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-4-107
 0.26 15.94 0.58 74-212 X-ray 1.55 homo-dimer 2 x FMN, 1 x NCO HHblits 0.28
3w1n.1.B
Dihydroorotate dehydrogenase (fumarate)
Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-iodoorotate
 0.26 15.94 0.58 74-212 X-ray 2.40 homo-dimer 2 x FMN, 1 x NCO, 2 x IRO HHblits 0.28
5z9y.1.A
Thiazole synthase
Crystal structure of Mycobacterium tuberculosis thiazole synthase (ThiG) complexed with DXP
 0.31 12.77 0.59 85-231 X-ray 1.48 homo-dimer 2 x DXP HHblits 0.26
3oa3.1.A
aldolase
Crystal structure of a putative deoxyribose-phosphate aldolase from Coccidioides immitis
 0.25 12.14 0.59 84-227 X-ray 1.60 monomer HHblits 0.27
4wzh.1.A
Dihydroorotate dehydrogenase
Dihydroorotate dehydrogenase from Leishmania Viannia braziliensis
 0.26 14.29 0.59 74-213 X-ray 2.12 homo-dimer 2 x FMN HHblits 0.27
7oj2.1.A
Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
Bacillus subtilis IMPDH in complex with Ap4A
 0.24 15.94 0.58 76-214 X-ray 1.76 homo-tetramer HHblits 0.28
3c3n.1.A
Dihydroorotate dehydrogenase
Crystal structure of dihydroorotate dehydrogenase from Trypanosoma cruzi strain Y
 0.26 15.22 0.58 74-212 X-ray 2.20 homo-tetramer 4 x FMN HHblits 0.28
1ho1.1.E
PYRIDOXINE 5'-PHOSPHATE SYNTHASE
CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE
 0.29 13.67 0.58 87-230 X-ray 2.00 homo-octamer HHblits 0.27
1ho1.1.C
PYRIDOXINE 5'-PHOSPHATE SYNTHASE
CRYSTAL STRUCTURE OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE
 0.28 13.67 0.58 87-230 X-ray 2.00 homo-octamer HHblits 0.27
1ixn.2.A
Pyridoxine 5'-Phosphate Synthase
Enzyme-Substrate Complex of Pyridoxine 5'-Phosphate Synthase
 0.29 13.67 0.58 87-230 X-ray 2.30 homo-dimer 2 x DXP, 2 x G3P HHblits 0.27
1m5w.1.A
Pyridoxal phosphate biosynthetic protein pdxJ
1.96 A Crystal Structure of Pyridoxine 5'-Phosphate Synthase in Complex with 1-deoxy-D-xylulose phosphate
 0.29 13.67 0.58 87-230 X-ray 1.96 homo-octamer 6 x DXP HHblits 0.27
1m5w.1.B
Pyridoxal phosphate biosynthetic protein pdxJ
1.96 A Crystal Structure of Pyridoxine 5'-Phosphate Synthase in Complex with 1-deoxy-D-xylulose phosphate
 0.29 13.67 0.58 87-230 X-ray 1.96 homo-octamer 6 x DXP HHblits 0.27
1m5w.1.D
Pyridoxal phosphate biosynthetic protein pdxJ
1.96 A Crystal Structure of Pyridoxine 5'-Phosphate Synthase in Complex with 1-deoxy-D-xylulose phosphate
 0.29 13.67 0.58 87-230 X-ray 1.96 homo-octamer 6 x DXP HHblits 0.27
1m5w.1.E
Pyridoxal phosphate biosynthetic protein pdxJ
1.96 A Crystal Structure of Pyridoxine 5'-Phosphate Synthase in Complex with 1-deoxy-D-xylulose phosphate
 0.29 13.67 0.58 87-230 X-ray 1.96 homo-octamer 6 x DXP HHblits 0.27
1m5w.1.F
Pyridoxal phosphate biosynthetic protein pdxJ
1.96 A Crystal Structure of Pyridoxine 5'-Phosphate Synthase in Complex with 1-deoxy-D-xylulose phosphate
 0.29 13.67 0.58 87-230 X-ray 1.96 homo-octamer 6 x DXP HHblits 0.27
1m5w.1.G
Pyridoxal phosphate biosynthetic protein pdxJ
1.96 A Crystal Structure of Pyridoxine 5'-Phosphate Synthase in Complex with 1-deoxy-D-xylulose phosphate
 0.27 13.67 0.58 87-230 X-ray 1.96 homo-octamer 6 x DXP HHblits 0.27
3c61.1.A
Dihydroorotate dehydrogenase
Crystal structure of dihydroorotate dehydrogenase from Leishmania donovani
 0.25 13.57 0.59 74-213 X-ray 1.80 homo-dimer 1 x AZI, 2 x FMN, 2 x ORO, 1 x DTU HHblits 0.27
2djx.1.A
Dihydroorotate Dehydrogenase
Crystal structure of native Trypanosoma cruzi dihydroorotate dehydrogenase
 0.27 15.22 0.58 74-212 X-ray 1.58 homo-dimer 1 x NCO, 2 x FMN HHblits 0.28
3tro.1.A
Dihydroorotate dehydrogenase
Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant D171A
 0.25 13.67 0.58 74-212 X-ray 1.86 homo-dimer 2 x FMN HHblits 0.27
1jub.1.A
dihydroorotate dehydrogenase A
The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A
 0.25 12.86 0.59 74-213 X-ray 1.40 homo-dimer 2 x MG, 2 x FMN HHblits 0.26
7mx6.1.A
Dihydroorotate dehydrogenase (fumarate)
Leishmania major dihydroorotate dehydrogenase in complex with [4-(1H-pyrrol-1-yl)phenyl]methanol
 0.26 12.86 0.59 74-213 X-ray 1.80 homo-dimer 2 x FMN, 1 x SNU HHblits 0.26
2e6d.1.B
Dihydroorotate dehydrogenase
Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with fumarate
 0.26 15.22 0.58 74-212 X-ray 1.94 homo-dimer 1 x NCO, 2 x FMN, 2 x FUM HHblits 0.27
7rmn.1.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Verrucomicrobium spinosum
 0.22 10.79 0.58 91-229 X-ray 1.21 homo-dimer HHblits 0.27
5u7s.1.A
Fructose-1,6-bisphosphate aldolase
Crystal structure of a fructose-bisphosphate aldolase, class II, Calvin cycle subtype from Acinetobacter baumannii
 0.25 14.60 0.58 74-213 X-ray 2.50 homo-tetramer HHblits 0.28
5u7s.1.B
Fructose-1,6-bisphosphate aldolase
Crystal structure of a fructose-bisphosphate aldolase, class II, Calvin cycle subtype from Acinetobacter baumannii
 0.25 14.60 0.58 74-213 X-ray 2.50 homo-tetramer HHblits 0.28
1jqv.1.A
Dihydroorotate dehydrogenase A
The K213E mutant of Lactococcus lactis Dihydroorotate dehydrogenase A
 0.26 12.86 0.59 74-213 X-ray 2.10 homo-dimer 2 x MG, 2 x FMN, 2 x ORO HHblits 0.26
1j2w.1.A
Aldolase protein
Tetrameric Structure of aldolase from Thermus thermophilus HB8
 0.25 11.43 0.59 83-227 X-ray 1.50 homo-tetramer HHblits 0.26
1j2w.1.C
Aldolase protein
Tetrameric Structure of aldolase from Thermus thermophilus HB8
 0.26 11.43 0.59 83-227 X-ray 1.50 homo-tetramer HHblits 0.26
3w9z.1.A
tRNA-dihydrouridine synthase C
Crystal structure of DusC
 0.26 7.91 0.58 74-216 X-ray 2.10 monomer 1 x FMN HHblits 0.27
4bfa.1.A
TRNA-DIHYDROURIDINE SYNTHASE C
Crystal structure of E. coli dihydrouridine synthase C (DusC)
 0.26 7.91 0.58 74-216 X-ray 1.65 monomer 1 x FMN HHblits 0.27
4bf9.1.A
TRNA-DIHYDROURIDINE SYNTHASE C
Crystal structure of E. coli dihydrouridine synthase C (DusC) (selenomethionine derivative)
 0.26 7.91 0.58 74-216 X-ray 2.60 monomer 1 x FMN HHblits 0.27
4yco.1.A
tRNA-dihydrouridine synthase C
E. coli dihydrouridine synthase C (DusC) in complex with tRNAPhe
 0.26 8.63 0.58 74-216 X-ray 2.10 monomer 1 x FMN HHblits 0.27
6ei9.1.A
tRNA-dihydrouridine synthase B
Crystal structure of E. coli tRNA-dihydrouridine synthase B (DusB)
 0.26 10.87 0.58 75-216 X-ray 2.55 monomer 1 x FMN HHblits 0.27
6ei9.2.A
tRNA-dihydrouridine synthase B
Crystal structure of E. coli tRNA-dihydrouridine synthase B (DusB)
 0.27 10.87 0.58 75-216 X-ray 2.55 monomer 1 x FMN HHblits 0.27
7myd.1.A
Dihydroorotate dehydrogenase (fumarate)
Leishmania major dihydroorotate dehydrogenase in complex with 5-amino-2-(1H-pyrrol-1-yl)benzonitrile
 0.27 12.86 0.59 74-213 X-ray 2.15 homo-dimer 2 x FMN, 1 x SNQ HHblits 0.26
3gye.1.A
Dihydroorotate dehydrogenase, putative
Didydroorotate dehydrogenase from Leishmania major
 0.27 12.86 0.59 74-213 X-ray 2.00 homo-dimer 2 x FMN HHblits 0.26
4jpg.1.A
Pyruvate kinase isozymes M1/M2
2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as Novel PKM2 Activators
 0.23 11.27 0.60 87-231 X-ray 2.33 homo-tetramer 4 x FBP, 2 x 1OX HHblits 0.25
4jpg.1.B
Pyruvate kinase isozymes M1/M2
2-((1H-benzo[d]imidazol-1-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-ones as Novel PKM2 Activators
 0.23 11.27 0.60 87-231 X-ray 2.33 homo-tetramer 4 x FBP, 2 x 1OX HHblits 0.25
6dgs.1.A
Dihydroorotate dehydrogenase (fumarate)
Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant Y142A
 0.25 12.14 0.59 74-213 X-ray 1.75 homo-dimer 2 x FMN HHblits 0.26
1f3x.1.A
PYRUVATE KINASE
S402P MUTANT OF RABBIT MUSCLE PYRUVATE KINASE
 0.23 11.27 0.60 87-231 X-ray 2.80 homo-tetramer 4 x K, 4 x MN, 4 x PYR HHblits 0.25
3qw3.1.A
Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative (Ompdcase-oprtase, putative)
Structure of Leishmania donovani OMP decarboxylase
 0.21 18.12 0.58 89-232 X-ray 1.70 homo-dimer HHblits 0.27
3f4n.1.A
Pyridoxine 5'-phosphate synthase
Crystal Structure of Pyridoxal Phosphate Biosynthetic Protein PdxJ from Yersinia pestis
 0.27 13.67 0.58 87-230 X-ray 2.40 homo-dimer 2 x PXP HHblits 0.26
2bx7.1.A
DIHYDROOROTATE DEHYDROGENASE
Crystal structure of L. lactis dihydroorotate dehydrogense A in complex with 3,5-dihydroxybenzoate
 0.26 13.67 0.58 74-212 X-ray 2.04 homo-dimer 2 x FMN, 2 x MG, 1 x 34D HHblits 0.26
6su2.1.D
Pyruvate kinase
Trypanosoma congolense pyruvate kinase in complex with citrate and glycerol
 0.24 12.14 0.59 87-230 X-ray 3.00 homo-tetramer 4 x FBP, 4 x MG HHblits 0.26
6su1.2.C
Pyruvate kinase
Trypanosoma congolense pyruvate kinase in complex with citrate and glycerol
 0.23 12.14 0.59 87-230 X-ray 3.00 homo-tetramer HHblits 0.26
6su1.1.C
Pyruvate kinase
Trypanosoma congolense pyruvate kinase in complex with citrate and glycerol
 0.23 12.14 0.59 87-230 X-ray 3.00 homo-tetramer HHblits 0.26
6su1.2.A
Pyruvate kinase
Trypanosoma congolense pyruvate kinase in complex with citrate and glycerol
 0.24 12.14 0.59 87-230 X-ray 3.00 homo-tetramer HHblits 0.26
6su1.1.A
Pyruvate kinase
Trypanosoma congolense pyruvate kinase in complex with citrate and glycerol
 0.24 12.14 0.59 87-230 X-ray 3.00 homo-tetramer HHblits 0.26
5u4n.1.A
Fructose-1
Crystal structure of a fructose-bisphosphate aldolase from Neisseria gonorrhoeae
 0.25 14.60 0.58 74-213 X-ray 1.60 homo-dimer HHblits 0.28
1t5a.1.A
Pyruvate kinase, M2 isozyme
Human Pyruvate Kinase M2
 0.25 11.27 0.60 87-232 X-ray 2.80 homo-tetramer 4 x FBP, 4 x OXL, 4 x MG, 4 x K HHblits 0.25
5ud1.1.A
Fructose-bisphosphate aldolase
Class II fructose-1,6-bisphosphate aldolase H180Q variant of Helicobacter pylori
 0.24 13.97 0.57 74-213 X-ray 1.80 homo-dimer 4 x ZN HHblits 0.28
1jqx.1.A
dihydroorotate dehydrogenase A
The R57A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
 0.25 12.95 0.58 74-212 X-ray 1.70 homo-dimer 2 x MG, 2 x FMN, 2 x ORO HHblits 0.26
3mhu.1.B
Dihydroorotate dehydrogenase
Crystal structure of dihydroorotate dehydrogenase from Leishmania major in complex with 5-Nitroorotic acid
 0.25 12.95 0.58 74-212 X-ray 1.85 homo-dimer 2 x FMN, 2 x EJZ HHblits 0.26
8hms.1.B
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant C474S
 0.25 11.27 0.60 87-232 X-ray 2.10 homo-tetramer 3 x FBP, 4 x OXL, 5 x MG HHblits 0.25
8hms.1.A
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant C474S
 0.24 11.27 0.60 87-232 X-ray 2.10 homo-tetramer 3 x FBP, 4 x OXL, 5 x MG HHblits 0.25
8hms.1.D
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant C474S
 0.25 11.27 0.60 87-232 X-ray 2.10 homo-tetramer 3 x FBP, 4 x OXL, 5 x MG HHblits 0.25
8g2e.1.A
Pyruvate kinase PKM
PKM2 bound to compound 2
 0.25 11.27 0.60 87-232 X-ray 1.84 homo-tetramer 4 x YII, 4 x OXL, 4 x MG HHblits 0.25
3gr4.1.C
Pyruvate kinase isozymes M1/M2
Activator-Bound Structure of Human Pyruvate Kinase M2
 0.25 11.27 0.60 87-232 X-ray 1.60 homo-tetramer 4 x FBP, 7 x TLA, 2 x DYY, 1 x ADP HHblits 0.25
6v74.1.A
Pyruvate kinase PKM
Crystal Structure of Human PKM2 in Complex with L-asparagine
 0.25 11.27 0.60 87-232 X-ray 2.32 homo-tetramer 4 x K, 4 x OXL, 4 x FBP, 4 x MG, 1 x ASN, 1 x 144 HHblits 0.25
6v75.1.D
Pyruvate kinase PKM
Crystal Structure of Human PKM2 in Complex with L-aspartate
 0.26 11.27 0.60 87-232 X-ray 2.85 homo-tetramer 6 x K, 4 x FBP, 4 x MG, 1 x OXL, 2 x ASP HHblits 0.25
6v75.1.C
Pyruvate kinase PKM
Crystal Structure of Human PKM2 in Complex with L-aspartate
 0.23 11.27 0.60 87-232 X-ray 2.85 homo-tetramer 6 x K, 4 x FBP, 4 x MG, 1 x OXL, 2 x ASP HHblits 0.25
5x1v.1.B
Pyruvate kinase PKM
PKM2 in complex with compound 2
 0.24 11.27 0.60 87-232 X-ray 2.10 homo-tetramer 4 x FBP, 4 x 7XX HHblits 0.25
3igs.1.A
N-acetylmannosamine-6-phosphate 2-epimerase 2
Structure of the Salmonella enterica N-acetylmannosamine-6-phosphate 2-epimerase
 0.30 15.22 0.58 82-228 X-ray 1.50 monomer 1 x 16G HHblits 0.27
3igs.2.A
N-acetylmannosamine-6-phosphate 2-epimerase 2
Structure of the Salmonella enterica N-acetylmannosamine-6-phosphate 2-epimerase
 0.30 15.22 0.58 82-228 X-ray 1.50 monomer HHblits 0.27
3e0v.1.A
Pyruvate kinase
Crystal structure of pyruvate kinase from Leishmania mexicana in complex with sulphate ions
 0.25 12.14 0.59 87-230 X-ray 3.30 homo-tetramer HHblits 0.26
3e0w.1.A
Pyruvate kinase
Crystal structure of pyruvate kinase from Leishmania mexicana
 0.25 12.14 0.59 87-230 X-ray 3.10 homo-tetramer HHblits 0.26
8p37.1.A
IMP dehydrogenase subunit
Structure a catalytically inactive mutant of the IMP dehydrogenase related protein GUAB3 from Synechocystis PCC 6803
 0.25 21.97 0.55 81-215 X-ray 1.22 homo-tetramer 4 x XMP, 4 x NAD HHblits 0.30
3tjx.1.A
Dihydroorotate dehydrogenase
Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant H174A
 0.27 12.95 0.58 74-212 X-ray 1.64 homo-dimer 2 x FMN HHblits 0.26
6ebs.1.A
Dihydroorotate dehydrogenase (fumarate)
Crystal structure of Leishmania major dihydroorotate dehydrogenase mutant H174A in complex with orotate
 0.26 12.95 0.58 74-212 X-ray 2.05 homo-dimer 2 x FMN, 2 x ORO, 1 x NI HHblits 0.26
3n9r.1.A
Fructose-bisphosphate aldolase
Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with N-(4-hydroxybutyl)-phosphoglycolohydroxamic acid, a competitive inhibitor
 0.22 14.71 0.57 74-213 X-ray 1.80 homo-dimer 2 x ZN, 2 x TD3 HHblits 0.28
3c4u.1.B
Fructose-bisphosphate aldolase
Structure of class II fructose-biphosphate aldolase from helicobacter pylori
 0.24 14.71 0.57 74-213 X-ray 1.83 homo-dimer 2 x ZN HHblits 0.28
2e28.1.A
Pyruvate kinase
Crystal structure analysis of pyruvate kinase from Bacillus stearothermophilus
 0.25 11.43 0.59 88-231 X-ray 2.40 homo-tetramer HHblits 0.26
3bjt.1.A
Pyruvate kinase isozymes M1/M2
Pyruvate kinase M2 is a phosphotyrosine binding protein
 0.23 11.35 0.59 88-231 X-ray 2.50 homo-tetramer 4 x OXL, 4 x MG HHblits 0.25
4yj5.1.A
Pyruvate kinase PKM
Crystal structure of PKM2 mutant
 0.23 11.35 0.59 88-231 X-ray 2.41 homo-tetramer 4 x PYR, 4 x MG, 4 x SER, 3 x FBP HHblits 0.25
4yj5.1.B
Pyruvate kinase PKM
Crystal structure of PKM2 mutant
 0.23 11.35 0.59 88-231 X-ray 2.41 homo-tetramer 4 x PYR, 4 x MG, 4 x SER, 3 x FBP HHblits 0.25
4yj5.1.D
Pyruvate kinase PKM
Crystal structure of PKM2 mutant
 0.23 11.35 0.59 88-231 X-ray 2.41 homo-tetramer 4 x PYR, 4 x MG, 4 x SER, 3 x FBP HHblits 0.25
5gvj.1.A
Enoyl-[acyl-carrier-protein] reductase [FMN]
Structure of FabK (M276A) mutant from Thermotoga maritima
 0.30 15.67 0.56 74-215 X-ray 1.90 homo-dimer HHblits 0.29
1jrb.1.A
dihydroorotate dehydrogenase A
The P56A mutant of Lactococcus lactis dihydroorotate dehydrogenase A
 0.25 11.43 0.59 74-213 X-ray 1.90 homo-dimer 2 x FMN, 2 x ORO HHblits 0.26
4rpp.1.A
Pyruvate kinase PKM
crystal structure of PKM2-K422R mutant bound with FBP
 0.22 11.35 0.59 88-231 X-ray 2.59 homo-tetramer 4 x FBP HHblits 0.25
5gvh.1.A
Enoyl-[acyl-carrier-protein] reductase [FMN]
Structure of FabK from Thermotoga maritima
 0.29 15.67 0.56 74-215 X-ray 2.29 homo-dimer 2 x FMN HHblits 0.29
8q57.1.A
Tagatose-1,6-bisphosphate aldolase kbaY
Crystal structure of class II SFP aldolase from Yersinia aldovae (YaSqiA-Zn-SO4) with bound sulfate ions
 0.27 15.44 0.57 74-213 X-ray 1.70 homo-tetramer 8 x ZN, 6 x BTB HHblits 0.28
3n25.1.A
Pyruvate kinase isozymes M1/M2
The structure of muscle pyruvate kinase in complex with proline, pyruvate, and Mn2+
 0.23 11.35 0.59 88-231 X-ray 2.41 homo-tetramer 4 x PRO, 4 x MN, 4 x PYR, 4 x K HHblits 0.25
6b6u.1.A
Pyruvate kinase PKM
Pyruvate Kinase M2 mutant - S437Y
 0.23 11.35 0.59 88-231 X-ray 1.35 homo-dimer 2 x MG, 2 x OXL, 2 x K, 2 x B3P HHblits 0.25
6b6u.1.B
Pyruvate kinase PKM
Pyruvate Kinase M2 mutant - S437Y
 0.22 11.35 0.59 88-231 X-ray 1.35 homo-dimer 2 x MG, 2 x OXL, 2 x K, 2 x B3P HHblits 0.25
8hmu.1.A
Pyruvate kinase PKM
Crystal Structure of PKM2 mutant R516C
 0.25 11.35 0.59 87-231 X-ray 2.50 homo-tetramer 5 x FBP, 5 x OXL, 7 x MG HHblits 0.25
4iql.1.A
Enoyl-(Acyl-carrier-protein) reductase II
Crystal Structure of Porphyromonas gingivalis Enoyl-ACP Reductase II (FabK) with cofactors NADPH and FMN
 0.29 13.97 0.57 74-215 X-ray 1.94 homo-dimer 2 x FMN, 4 x NDP HHblits 0.28
3bjf.1.A
Pyruvate kinase isozymes M1/M2
Pyruvate kinase M2 is a phosphotyrosine binding protein
 0.24 11.35 0.59 88-232 X-ray 2.03 homo-tetramer 4 x FBP, 4 x OXL, 4 x K, 4 x MG HHblits 0.25
4qgc.1.A
Pyruvate kinase PKM
crystal structure of PKM2-K422R mutant
 0.22 11.35 0.59 88-231 X-ray 2.30 homo-tetramer 4 x K HHblits 0.25
4qgc.1.B
Pyruvate kinase PKM
crystal structure of PKM2-K422R mutant
 0.22 11.35 0.59 88-231 X-ray 2.30 homo-tetramer 4 x K HHblits 0.25
4qgc.1.D
Pyruvate kinase PKM
crystal structure of PKM2-K422R mutant
 0.22 11.35 0.59 88-231 X-ray 2.30 homo-tetramer 4 x K HHblits 0.25
3bo9.1.A
Putative nitroalkan dioxygenase
Crystal structure of putative nitroalkan dioxygenase (TM0800) from Thermotoga maritima at 2.71 A resolution
 0.29 15.67 0.56 74-215 X-ray 2.71 homo-dimer 9 x 2PE HHblits 0.29
3l52.1.A
Orotidine 5'-phosphate decarboxylase
Crystal structure of putative orotidine 5'-phosphate decarboxylase from Streptomyces avermitilis MA-4680
 0.17 14.49 0.58 87-230 X-ray 1.35 homo-dimer HHblits 0.26
5c2x.1.A
Deoxyribose-phosphate aldolase
Crystal structure of deoxyribose-phosphate aldolase from Colwellia psychrerythraea (tetragonal form)
 0.21 12.86 0.59 84-227 X-ray 2.11 homo-dimer HHblits 0.25
6nu5.1.A
Pyruvate kinase PKM
Pyruvate Kinase M2 Mutant - S437Y in Complex with L-cysteine
 0.25 11.35 0.59 87-231 X-ray 1.60 homo-dimer 2 x CYS, 2 x OXL, 2 x B3P, 2 x MG, 2 x K HHblits 0.25
6nu5.1.B
Pyruvate kinase PKM
Pyruvate Kinase M2 Mutant - S437Y in Complex with L-cysteine
 0.25 11.35 0.59 87-231 X-ray 1.60 homo-dimer 2 x CYS, 2 x OXL, 2 x B3P, 2 x MG, 2 x K HHblits 0.25
7l21.1.A
Pyruvate kinase PKM
Pyruvate Kinase M2 mutant-N70D
 0.25 11.35 0.59 87-231 X-ray 2.29 homo-tetramer 4 x OXL, 4 x MG, 4 x FBP HHblits 0.25
7r6y.1.A
Pyruvate kinase PKM
E117K mutant pyruvate kinase from rabbit muscle
 0.25 11.35 0.59 87-231 X-ray 2.25 homo-tetramer 4 x OXL, 4 x MG HHblits 0.25
8f5t.1.A
Pyruvate kinase PKM
Rabbit muscle pyruvate kinase in complex with sodium and magnesium
 0.25 11.35 0.59 87-231 X-ray 2.41 homo-tetramer 4 x MG HHblits 0.25
8f6m.1.C
Pyruvate kinase PKM
Complex of Rabbit muscle pyruvate kinase with ADP and the phosphonate analogue of PEP mimicking the Michaelis complex.
 0.25 11.35 0.59 87-231 X-ray 2.15 homo-tetramer 2 x ADP, 5 x SIN, 7 x MN, 4 x K, 4 x ALA, 3 x GZ3 HHblits 0.25
8f6m.1.A
Pyruvate kinase PKM
Complex of Rabbit muscle pyruvate kinase with ADP and the phosphonate analogue of PEP mimicking the Michaelis complex.
 0.25 11.35 0.59 87-231 X-ray 2.15 homo-tetramer 2 x ADP, 5 x SIN, 7 x MN, 4 x K, 4 x ALA, 3 x GZ3 HHblits 0.25
8f6m.1.B
Pyruvate kinase PKM
Complex of Rabbit muscle pyruvate kinase with ADP and the phosphonate analogue of PEP mimicking the Michaelis complex.
 0.26 11.35 0.59 87-231 X-ray 2.15 homo-tetramer 2 x ADP, 5 x SIN, 7 x MN, 4 x K, 4 x ALA, 3 x GZ3 HHblits 0.25
2z6j.1.A
Trans-2-enoyl-ACP reductase II
Crystal Structure of S. pneumoniae Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor
 0.29 18.66 0.56 74-215 X-ray 2.30 homo-dimer 4 x CA, 2 x FMN, 2 x TUI HHblits 0.29
3srf.1.A
Pyruvate kinase isozymes M1/M2
Human M1 pyruvate kinase
 0.25 11.35 0.59 87-231 X-ray 2.85 homo-tetramer 4 x K, 4 x MG, 4 x PYR HHblits 0.25
7skj.1.A
Triosephosphate isomerase
Crystal structure of chloroplast triosephosphate isomerase from Cuscuta australis
 0.21 13.97 0.57 90-225 X-ray 1.90 homo-dimer HHblits 0.27
3khj.1.A
Inosine-5-monophosphate dehydrogenase
C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64
 0.27 20.15 0.56 76-214 X-ray 2.80 homo-tetramer 4 x IMP, 2 x C64 HHblits 0.29
3khj.1.B
Inosine-5-monophosphate dehydrogenase
C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64
 0.27 20.15 0.56 76-214 X-ray 2.80 homo-tetramer 4 x IMP, 2 x C64 HHblits 0.29
3khj.1.C
Inosine-5-monophosphate dehydrogenase
C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64
 0.27 20.15 0.56 76-214 X-ray 2.80 homo-tetramer 4 x IMP, 2 x C64 HHblits 0.29
1f3w.1.A
PYRUVATE KINASE
RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE
 0.26 11.35 0.59 87-231 X-ray 3.00 homo-tetramer 4 x K, 4 x MN, 4 x PYR HHblits 0.24
2g50.1.A
Pyruvate kinase isozymes M1/M2
The location of the allosteric amino acid binding site of muscle pyruvate kinase.
 0.23 11.43 0.59 88-231 X-ray 1.65 homo-tetramer 4 x MN, 4 x K, 4 x ALA, 4 x PYR, 1 x ETE HHblits 0.25
1a49.2.C
PYRUVATE KINASE
BIS MG-ATP-K-OXALATE COMPLEX OF PYRUVATE KINASE
 0.23 11.43 0.59 88-231 X-ray 2.10 homo-tetramer 4 x K, 4 x OXL, 4 x MG, 3 x ATP HHblits 0.25
1a49.1.B
PYRUVATE KINASE
BIS MG-ATP-K-OXALATE COMPLEX OF PYRUVATE KINASE
 0.23 11.43 0.59 88-231 X-ray 2.10 homo-tetramer 4 x K, 4 x OXL, 4 x MG, 3 x ATP HHblits 0.25
1a49.2.B
PYRUVATE KINASE
BIS MG-ATP-K-OXALATE COMPLEX OF PYRUVATE KINASE
 0.24 11.43 0.59 88-231 X-ray 2.10 homo-tetramer 4 x K, 4 x OXL, 4 x MG, 3 x ATP HHblits 0.25
1aqf.1.D
PYRUVATE KINASE
PYRUVATE KINASE FROM RABBIT MUSCLE WITH MG, K, AND L-PHOSPHOLACTATE
 0.24 11.43 0.59 88-231 X-ray 2.70 homo-tetramer 4 x K, 4 x MG, 4 x PEQ HHblits 0.25
1aqf.2.C
PYRUVATE KINASE
PYRUVATE KINASE FROM RABBIT MUSCLE WITH MG, K, AND L-PHOSPHOLACTATE
 0.23 11.43 0.59 88-231 X-ray 2.70 homo-tetramer 4 x K, 4 x MG, 4 x PEQ HHblits 0.25
1aqf.1.A
PYRUVATE KINASE
PYRUVATE KINASE FROM RABBIT MUSCLE WITH MG, K, AND L-PHOSPHOLACTATE
 0.24 11.43 0.59 88-231 X-ray 2.70 homo-tetramer 4 x K, 4 x MG, 4 x PEQ HHblits 0.25
5ucs.1.A
Fructose-bisphosphate aldolase
Class II fructose-1,6-bisphosphate aldolase E149A variant of Helicobacter pylori
 0.25 13.24 0.57 74-213 X-ray 1.41 homo-dimer 2 x ZN HHblits 0.27
5ucz.1.A
Fructose-bisphosphate aldolase
Class II fructose-1,6-bisphosphate aldolase E149A variant of Helicobacter pylori with DHAP
 0.23 13.24 0.57 74-213 X-ray 1.78 homo-dimer 4 x ZN, 2 x 13P HHblits 0.27
6wp6.1.A
Pyruvate kinase PKM
Pyruvate Kinase M2 mutant-S37E K433E
 0.24 11.43 0.59 88-231 X-ray 2.45 homo-tetramer 4 x MG, 2 x OXL HHblits 0.25
6wp6.1.B
Pyruvate kinase PKM
Pyruvate Kinase M2 mutant-S37E K433E
 0.25 11.43 0.59 88-231 X-ray 2.45 homo-tetramer 4 x MG, 2 x OXL HHblits 0.25
4y90.1.A
Triosephosphate isomerase
Crystal structure of Triosephosphate Isomerase from Deinococcus radiodurans
 0.22 14.18 0.56 90-223 X-ray 2.10 homo-dimer 3 x CA HHblits 0.28
4qg8.1.A
Pyruvate kinase PKM
crystal structure of PKM2-K305Q mutant
 0.25 11.43 0.59 88-231 X-ray 2.30 homo-tetramer 3 x MG, 3 x K HHblits 0.25
4qg8.1.B
Pyruvate kinase PKM
crystal structure of PKM2-K305Q mutant
 0.25 11.43 0.59 88-231 X-ray 2.30 homo-tetramer 3 x MG, 3 x K HHblits 0.25
5ucn.1.A
Fructose-bisphosphate aldolase
Class II fructose-1,6-bisphosphate aldolase E142A variant of Helicobacter pylori with DHAP
 0.23 13.24 0.57 74-213 X-ray 1.67 homo-dimer 4 x ZN, 2 x 13P HHblits 0.27
5c6m.1.A
Deoxyribose-phosphate aldolase
Crystal structure of deoxyribose-phosphate aldolase from Shewanella halifaxensis
 0.21 13.77 0.58 84-227 X-ray 1.76 homo-dimer HHblits 0.26
3g2g.1.A
Pyruvate kinase isozymes M1/M2
S437Y Mutant of human muscle pyruvate kinase, isoform M2
 0.24 11.43 0.59 88-231 X-ray 2.00 homo-tetramer HHblits 0.25
4qg9.1.A
Pyruvate kinase PKM
crystal structure of PKM2-R399E mutant
 0.22 10.71 0.59 88-231 X-ray 2.38 homo-tetramer 3 x MG HHblits 0.25
4qg9.1.B
Pyruvate kinase PKM
crystal structure of PKM2-R399E mutant
 0.23 10.71 0.59 88-231 X-ray 2.38 homo-tetramer 3 x MG HHblits 0.25
3u2z.1.A
Pyruvate kinase isozymes M1/M2
Activator-Bound Structure of Human Pyruvate Kinase M2
 0.25 11.43 0.59 88-231 X-ray 2.10 homo-tetramer 4 x FBP, 2 x 07T HHblits 0.25
3u2z.1.B
Pyruvate kinase isozymes M1/M2
Activator-Bound Structure of Human Pyruvate Kinase M2
 0.25 11.43 0.59 88-231 X-ray 2.10 homo-tetramer 4 x FBP, 2 x 07T HHblits 0.25
4g1n.1.C
Pyruvate kinase isozymes M1/M2
PKM2 in complex with an activator
 0.24 11.43 0.59 88-231 X-ray 2.30 homo-tetramer 4 x OXL, 4 x MG, 2 x NZT HHblits 0.25
4g1n.1.B
Pyruvate kinase isozymes M1/M2
PKM2 in complex with an activator
 0.24 11.43 0.59 88-231 X-ray 2.30 homo-tetramer 4 x OXL, 4 x MG, 2 x NZT HHblits 0.25
4g1n.1.A
Pyruvate kinase isozymes M1/M2
PKM2 in complex with an activator
 0.24 11.43 0.59 88-231 X-ray 2.30 homo-tetramer 4 x OXL, 4 x MG, 2 x NZT HHblits 0.25
4qg6.1.A
Pyruvate kinase PKM
crystal structure of PKM2-Y105E mutant
 0.24 11.43 0.59 88-231 X-ray 3.21 homo-tetramer 4 x PRO HHblits 0.25
4qg6.1.B
Pyruvate kinase PKM
crystal structure of PKM2-Y105E mutant
 0.25 11.43 0.59 88-231 X-ray 3.21 homo-tetramer 4 x PRO HHblits 0.25
7e1r.1.A
2-nitropropane dioxygenase
Crystal structure of Dehydrogenase/isomerase FabX from Helicobacter pylori in complex with holo-ACP
 0.25 13.87 0.58 75-215 X-ray 2.80 hetero-1-1-mer 1 x FMN, 1 x SF4, 1 x PN7 HHblits 0.26
7e1q.1.A
2-nitropropane dioxygenase
Crystal structure of dehydrogenase/isomerase FabX from Helicobacter pylori
 0.26 13.87 0.58 75-215 X-ray 1.70 monomer 1 x SF4, 1 x FMN HHblits 0.26
7e1s.1.A
2-nitropropane dioxygenase
Crystal structure of dehydrogenase/isomerase FabX from Helicobacter pylori in complex with octanoyl-ACP
 0.25 13.87 0.58 75-215 X-ray 2.31 hetero-1-1-mer 1 x FMN, 1 x SF4, 1 x 66S HHblits 0.26
2h6r.1.A
Triosephosphate isomerase
Crystal Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii
 0.29 17.42 0.55 90-226 X-ray 2.30 homo-tetramer HHblits 0.29
2h6r.1.B
Triosephosphate isomerase
Crystal Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii
 0.28 17.42 0.55 90-226 X-ray 2.30 homo-tetramer HHblits 0.29
2h6r.1.C
Triosephosphate isomerase
Crystal Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii
 0.29 17.42 0.55 90-226 X-ray 2.30 homo-tetramer HHblits 0.29
2h6r.2.B
Triosephosphate isomerase
Crystal Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii
 0.28 17.42 0.55 90-226 X-ray 2.30 homo-tetramer HHblits 0.29
4nvt.1.A
Triosephosphate isomerase
Crystal Structure of Triosephosphate Isomerase from Brucella melitensis
 0.21 15.67 0.56 91-224 X-ray 2.10 homo-dimer HHblits 0.28
1pkn.1.A
PYRUVATE KINASE
STRUCTURE OF RABBIT MUSCLE PYRUVATE KINASE COMPLEXED WITH MN2+, K+, AND PYRUVATE
 0.25 11.43 0.59 88-231 X-ray 2.90 monomer 1 x K, 1 x MN, 1 x PYR HHblits 0.24
5ujw.3.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4
 0.22 16.42 0.56 91-224 X-ray 2.65 homo-dimer HHblits 0.28
5ujw.1.B
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4
 0.21 16.42 0.56 91-224 X-ray 2.65 homo-dimer 1 x 13P HHblits 0.28
5ujw.2.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4
 0.22 16.42 0.56 91-224 X-ray 2.65 homo-dimer 1 x 13P HHblits 0.28
5ujw.2.B
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4
 0.21 16.42 0.56 91-224 X-ray 2.65 homo-dimer 1 x 13P HHblits 0.28
5ujw.1.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4
 0.22 16.42 0.56 91-224 X-ray 2.65 homo-dimer 1 x 13P HHblits 0.28
5ujw.4.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Francisella tularensis subsp. tularensis SCHU S4
 0.21 16.42 0.56 91-224 X-ray 2.65 homo-dimer HHblits 0.28
3pm6.1.A
Putative fructose-bisphosphate aldolase
Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR
 0.20 12.41 0.58 74-212 X-ray 2.20 homo-dimer 2 x ZN HHblits 0.26
4k6a.1.A
Triosephosphate isomerase
Revised Crystal Structure of apo-form of Triosephosphate Isomerase (tpiA) from Escherichia coli at 1.8 Angstrom Resolution.
 0.22 13.33 0.57 90-224 X-ray 1.80 homo-dimer HHblits 0.27
4mva.1.B
Triosephosphate isomerase
1.43 Angstrom Resolution Crystal Structure of Triosephosphate Isomerase (tpiA) from Escherichia coli in Complex with Acetyl Phosphate.
 0.21 13.33 0.57 90-224 X-ray 1.43 homo-dimer 2 x UVW HHblits 0.27
5css.1.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Thermoplasma acidophilum with glycerol 3-phosphate
 0.26 15.04 0.56 90-227 X-ray 2.17 homo-dimer 2 x G3P HHblits 0.28
5csr.1.B
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Thermoplasma acidophilium
 0.24 15.04 0.56 90-227 X-ray 1.94 homo-dimer HHblits 0.28
5csr.1.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Thermoplasma acidophilium
 0.26 15.04 0.56 90-227 X-ray 1.94 homo-dimer HHblits 0.28
8q58.1.A
Ketose-bisphosphate aldolase
Crystal structure of metal-dependent classII sulfofructosephosphate aldolase (SFPA) from Hafnia paralvei HpSqiA-Zn
 0.26 17.29 0.56 74-213 X-ray 1.70 homo-tetramer 8 x ZN HHblits 0.28
8q5a.1.A
Ketose-bisphosphate aldolase
Crystal structure of metal-dependent class II sulfofructosephosphate aldolase from Hafnia paralvei HpSqiA-Zn in complex with dihydroxyacetone phosphate (DHAP)
 0.26 17.29 0.56 74-213 X-ray 2.80 homo-tetramer 8 x ZN, 4 x 13P HHblits 0.28
3gb6.1.A
Fructose-bisphosphate aldolase
Structure of Giardia fructose-1,6-biphosphate aldolase D83A mutant in complex with fructose-1,6-bisphosphate
 0.25 13.97 0.57 74-211 X-ray 2.00 homo-dimer 4 x ZN, 2 x P6F HHblits 0.26
3s6d.1.A
Putative triosephosphate isomerase
Crystal structure of a putative triosephosphate isomerase from Coccidioides immitis
 0.22 10.95 0.58 90-226 X-ray 2.20 homo-dimer HHblits 0.26
4mkn.1.A
Triosephosphate isomerase
Crystal structure of chloroplastic triosephosphate isomerase from Chlamydomonas reinhardtii at 1.1 A of resolution
 0.19 14.07 0.57 90-224 X-ray 1.10 homo-dimer HHblits 0.27
4xp7.1.A
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
Crystal structure of Human tRNA dihydrouridine synthase 2
 0.21 12.59 0.57 5-152 X-ray 1.90 monomer 1 x FNR HHblits 0.27
1ox6.2.A
Imidazole glycerol phosphate synthase hisHF
TOWARDS UNDERSTANDING THE MECHANISM OF THE COMPLEX CYCLIZATION REACTION CATALYZED BY IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE
 0.24 10.29 0.57 75-214 X-ray 2.40 monomer 1 x NI, 1 x POP HHblits 0.26
4xp7.1.A
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
Crystal structure of Human tRNA dihydrouridine synthase 2
 0.25 9.49 0.58 75-215 X-ray 1.90 monomer 1 x FNR HHblits 0.26
7l00.1.A
Enoyl-Acyl Carrier Protein Reductase FabK
Crystal Structure of C. difficile Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor
 0.28 14.93 0.56 74-215 X-ray 1.72 homo-dimer 2 x FMN, 2 x XCJ HHblits 0.27
7l00.1.B
Enoyl-Acyl Carrier Protein Reductase FabK
Crystal Structure of C. difficile Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor
 0.29 14.93 0.56 74-215 X-ray 1.72 homo-dimer 2 x FMN, 2 x XCJ HHblits 0.27
4ohq.1.A
Triosephosphate isomerase, chloroplastic
Crystal structure of chloroplast triose phosphate isomerase from Arabidopsis thaliana
 0.21 13.33 0.57 91-225 X-ray 2.15 homo-dimer HHblits 0.27
5ahn.1.A
INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE
IMP-bound form of the D199N mutant of IMPDH from Pseudomonas aeruginosa
 0.24 15.56 0.57 78-214 X-ray 1.65 homo-tetramer 4 x IMP, 4 x MG HHblits 0.27
2jgq.1.A
TRIOSEPHOSPHATE ISOMERASE
Kinetics and structural properties of triosephosphate isomerase from Helicobacter pylori
 0.22 15.04 0.56 91-223 X-ray 2.30 homo-dimer 1 x QGA HHblits 0.28
6ofu.1.B
YdjI aldolase
X-ray crystal structure of the YdjI aldolase from Escherichia coli K12
 0.24 16.30 0.57 74-213 X-ray 1.75 homo-tetramer 5 x ZN HHblits 0.27
6ofu.1.A
YdjI aldolase
X-ray crystal structure of the YdjI aldolase from Escherichia coli K12
 0.22 16.30 0.57 74-213 X-ray 1.75 homo-tetramer 5 x ZN HHblits 0.27
1w8s.1.A
FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I
The mechanism of the Schiff Base Forming Fructose-1,6-bisphosphate Aldolase: Structural analysis of reaction intermediates
 0.26 13.33 0.57 87-232 X-ray 1.85 homo-pentamer 5 x FBP HHblits 0.26
6w6a.1.A
Pyridoxine 5'-phosphate synthase
Crystal structure of a pyridoxine 5'-phosphate synthease from Stenotrophomonas maltophilia K279a
 0.27 13.33 0.57 87-226 X-ray 2.45 homo-dimer HHblits 0.26
3kxq.1.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from bartonella henselae at 1.6A resolution
 0.22 13.33 0.57 90-224 X-ray 1.60 homo-dimer HHblits 0.26
4to8.1.A
Fructose-1,6-bisphosphate aldolase, class II
Methicillin-Resistant Staphylococcus Aureus Class IIb Fructose 1,6-Bisphosphate Aldolase
 0.24 15.56 0.57 74-212 X-ray 2.10 homo-dimer 2 x ZN, 2 x FLC HHblits 0.26
7z4r.1.A
Pyruvate kinase
Plasmodium falciparum pyruvate kinase mutant - C343A
 0.25 8.70 0.58 90-231 X-ray 2.00 homo-tetramer 4 x MG, 4 x K HHblits 0.25
7rpn.1.A
Triosephosphate isomerase
Crystal structure of triosephosphate isomerase from Bacteroides thetaiotaomicron
 0.21 15.15 0.55 91-223 X-ray 1.37 homo-dimer HHblits 0.28
7z4m.1.A
Pyruvate kinase
Plasmodium falciparum pyruvate kinase complexed with Mg2+ and K+
 0.26 8.70 0.58 90-231 X-ray 1.90 homo-tetramer 4 x MG, 4 x K HHblits 0.25
7z4n.1.A
Pyruvate kinase
Plasmodium falciparum pyruvate kinase complexed with pyruvate
 0.25 8.70 0.58 90-231 X-ray 1.80 homo-tetramer 4 x MG, 4 x K, 4 x PYR, 4 x MES HHblits 0.25
2gjl.1.A
hypothetical protein PA1024
Crystal Structure of 2-nitropropane dioxygenase
 0.30 13.33 0.57 74-215 X-ray 2.00 monomer 1 x FMN HHblits 0.26
6e2a.1.A
Nitronate monooxygenase
Crystal structure of NADH:quinone reductase PA1024 from Pseudomonas aeruginosa PAO1 in complex with NAD+
 0.29 12.50 0.57 74-215 X-ray 2.20 homo-dimer 2 x FMN, 2 x NAD HHblits 0.26
6ksh.1.A
Pyruvate kinase
Crystal structure of pyruvate kinase (PYK) from Plasmodium falciparum in complex with oxalate and ATP
 0.25 8.70 0.58 90-231 X-ray 2.60 homo-tetramer 7 x MG, 4 x ATP, 4 x K, 4 x OXL HHblits 0.25
7z4q.1.A
Pyruvate kinase
Plasmodium falciparum pyruvate kinase mutant - C49A
 0.24 8.70 0.58 90-231 X-ray 2.10 homo-tetramer 4 x MG HHblits 0.25
6nee.1.A
TRIOSEPHOSPHATE ISOMERASE
Crystal structure of a reconstructed ancestor of Triosephosphate isomerase from eukaryotes
 0.23 17.56 0.55 90-221 X-ray 1.90 homo-dimer 2 x PGH HHblits 0.29
8vcw.1.A
Biotin synthase
X-Ray Crystal Structure of the biotin synthase from B. obeum
 0.26 19.53 0.54 87-215 X-ray 1.35 monomer 1 x SAM, 1 x BTB, 1 x Q46, 1 x SF4, 1 x DTB, 1 x FE HHblits 0.30
2qjg.1.A
Putative aldolase MJ0400
M. jannaschii ADH synthase complexed with F1,6P
 0.28 16.03 0.55 89-231 X-ray 2.60 homo-10-mer 10 x F2P HHblits 0.28
7nc7.1.A
Fructose-bisphosphate aldolase
Crystal structure of fructose-bisphosphate aldolases FBAC from Bacillus methanolicus
 0.23 13.33 0.57 74-212 X-ray 2.20 homo-dimer 2 x 13P HHblits 0.26
7nc7.1.B
Fructose-bisphosphate aldolase
Crystal structure of fructose-bisphosphate aldolases FBAC from Bacillus methanolicus
 0.24 13.33 0.57 74-212 X-ray 2.20 homo-dimer 2 x 13P HHblits 0.26
3q94.1.A
Fructose-bisphosphate aldolase, class II
The crystal structure of fructose 1,6-bisphosphate aldolase from Bacillus anthracis str. 'Ames Ancestor
 0.25 12.50 0.57 74-213 X-ray 2.30 homo-dimer 10 x ZN, 2 x 13P HHblits 0.25
4wxz.1.A
Pyridoxal biosynthesis lyase PdxS
PdxS (G. stearothermophilus) co-crystallized with R5P
 0.24 11.11 0.57 77-233 X-ray 2.70 homo-12-mer HHblits 0.26
6ei9.1.A
tRNA-dihydrouridine synthase B
Crystal structure of E. coli tRNA-dihydrouridine synthase B (DusB)
 0.24 14.29 0.56 6-152 X-ray 2.55 monomer 1 x FMN HHblits 0.27
6ei9.2.A
tRNA-dihydrouridine synthase B
Crystal structure of E. coli tRNA-dihydrouridine synthase B (DusB)
 0.24 14.29 0.56 6-152 X-ray 2.55 monomer 1 x FMN HHblits 0.27
6w4u.1.A
Triosephosphate isomerase
Crystal structure of Triosephosphate isomerase from Stenotrophomonas maltophilia K279a
 0.21 15.04 0.56 91-223 X-ray 1.70 homo-dimer HHblits 0.27
4iot.1.A
Triosephosphate isomerase
High-resolution Structure of Triosephosphate isomerase from E. coli
 0.22 13.53 0.56 91-224 X-ray 1.85 homo-dimer HHblits 0.27
2qr6.1.A
IMP dehydrogenase/GMP reductase
Crystal structure of IMP dehydrogenase/GMP reductase-like protein (NP_599840.1) from Corynebacterium glutamicum ATCC 13032 Kitasato at 1.50 A resolution
 0.26 15.27 0.55 80-214 X-ray 1.50 homo-tetramer HHblits 0.28
3khd.1.A
Pyruvate kinase
Crystal Structure of PFF1300w.
 0.25 8.76 0.58 90-230 X-ray 2.70 homo-tetramer HHblits 0.25
1aw1.1.A
TRIOSEPHOSPHATE ISOMERASE
TRIOSEPHOSPHATE ISOMERASE OF VIBRIO MARINUS COMPLEXED WITH 2-PHOSPHOGLYCOLATE
 0.21 14.39 0.55 91-222 X-ray 2.70 homo-dimer 2 x PGA HHblits 0.28
1aw2.1.B
TRIOSEPHOSPHATE ISOMERASE
TRIOSEPHOSPHATE ISOMERASE OF VIBRIO MARINUS
 0.21 14.39 0.55 91-222 X-ray 2.65 homo-dimer HHblits 0.28
8ofw.1.A
Dihydroorotate dehydrogenase (quinone)
Crystal structure of the full-length dihydroorotate dehydrogenase from Mycobacterium tuberculosis
 0.25 14.39 0.55 96-227 X-ray 3.80 monomer 1 x FMN HHblits 0.28
8ofw.2.A
Dihydroorotate dehydrogenase (quinone)
Crystal structure of the full-length dihydroorotate dehydrogenase from Mycobacterium tuberculosis
 0.25 14.39 0.55 96-227 X-ray 3.80 monomer 1 x FMN HHblits 0.28
1ojx.1.A
FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I
Crystal structure of an Archaeal fructose 1,6-bisphosphate aldolase
 0.28 13.43 0.56 88-232 X-ray 1.90 homo-pentamer HHblits 0.26
3ta6.1.A
Triosephosphate isomerase
Structure of Mycobacterium tuberculosis triosephosphate isomerase
 0.24 13.43 0.56 90-223 X-ray 1.41 homo-dimer 1 x FLC HHblits 0.26
3tao.1.A
Triosephosphate isomerase
Structure of Mycobacterium tuberculosis triosephosphate isomerase bound to phosphoglycolohydroxamate
 0.23 13.43 0.56 90-223 X-ray 1.45 homo-dimer 2 x PGH HHblits 0.26
3gg8.1.C
Pyruvate kinase
Crystal structure of the Toxoplasma gondii Pyruvate Kinase N terminal truncated
 0.23 8.76 0.58 90-230 X-ray 2.21 homo-tetramer HHblits 0.25
3gg8.1.A
Pyruvate kinase
Crystal structure of the Toxoplasma gondii Pyruvate Kinase N terminal truncated
 0.24 8.76 0.58 90-230 X-ray 2.21 homo-tetramer HHblits 0.25
3gg8.1.B
Pyruvate kinase
Crystal structure of the Toxoplasma gondii Pyruvate Kinase N terminal truncated
 0.24 8.76 0.58 90-230 X-ray 2.21 homo-tetramer HHblits 0.25
3eoe.1.B
Pyruvate kinase
Crystal Structure of Pyruvate Kinase from toxoplasma gondii, 55.m00007
 0.23 8.76 0.58 90-230 X-ray 2.31 homo-tetramer HHblits 0.25
7n8u.1.A
Triosephosphate isomerase
Crystal structure of Triosephosphate isomerase from Candidatus Prometheoarchaeum syntrophicum
 0.21 17.56 0.55 91-221 X-ray 1.98 homo-dimer HHblits 0.28
3aal.1.A
Probable endonuclease 4
Crystal Structure of endonuclease IV from Geobacillus kaustophilus
 0.23 12.69 0.56 3-146 X-ray 1.60 monomer 1 x CAC, 2 x FE, 1 x ZN HHblits 0.26
4yco.1.A
tRNA-dihydrouridine synthase C
E. coli dihydrouridine synthase C (DusC) in complex with tRNAPhe
 0.22 10.45 0.56 5-152 X-ray 2.10 monomer 1 x FMN HHblits 0.26
2yce.1.A
FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1
Structure of an Archaeal fructose-1,6-bisphosphate aldolase with the catalytic Lys covalently bound to the carbinolamine intermediate of the substrate.
 0.26 13.43 0.56 87-231 X-ray 1.93 homo-pentamer 5 x M2P HHblits 0.26
2isw.1.A
Putative fructose-1,6-bisphosphate aldolase
Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate
 0.25 13.43 0.56 74-211 X-ray 1.75 homo-dimer 1 x ZN, 1 x PGH HHblits 0.26
2isv.1.B
Putative fructose-1,6-bisphosphate aldolase
Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate
 0.26 13.43 0.56 74-211 X-ray 2.30 homo-dimer 2 x ZN, 2 x PGH HHblits 0.26
2isw.1.B
Putative fructose-1,6-bisphosphate aldolase
Structure of Giardia fructose-1,6-biphosphate aldolase in complex with phosphoglycolohydroxamate
 0.26 13.43 0.56 74-211 X-ray 1.75 homo-dimer 1 x ZN, 1 x PGH HHblits 0.26
4y9a.1.A
Triosephosphate isomerase
Crystal structure of Triosephosphate Isomerase from Streptomyces coelicolor
 0.23 15.91 0.55 90-221 X-ray 2.29 homo-dimer HHblits 0.27
7ncc.1.A
Putative class II fructose-1,6-bisphosphate aldolase
Crystal structure of fructose-bisphosphate aldolase FBAP from Bacillus methanolicus
 0.24 14.07 0.57 74-212 X-ray 2.00 homo-dimer 1 x MLT, 1 x IMD HHblits 0.26
1y0e.1.A
Putative N-acetylmannosamine-6-phosphate 2-epimerase
Crystal structure of putative ManNAc-6-P epimerase from Staphylococcus aureus (strain N315)
 0.27 11.36 0.55 88-227 X-ray 1.95 monomer HHblits 0.27
6p6f.1.A
I53-50A.1NT1
BG505 SOSIP-I53-50NP
 0.29 15.38 0.55 85-230 EM 0.00 hetero-1-1-mer HHblits 0.28
1tre.1.A
TRIOSEPHOSPHATE ISOMERASE
THE STRUCTURE OF TRIOSEPHOSPHATE ISOMERASE FROM ESCHERICHIA COLI DETERMINED AT 2.6 ANGSTROM RESOLUTION
 0.22 12.03 0.56 91-224 X-ray 2.60 homo-dimer HHblits 0.27
7mfn.1.A
N-acetylmannosamine-6-phosphate 2-epimerase
N-Acetylmannosamine-6-phosphate 2-epimerase E180A from Staphylococcus aureus (strain MRSA USA300)
 0.28 10.53 0.56 87-227 X-ray 1.55 homo-dimer HHblits 0.27
1rv8.1.B
fructose-1,6-bisphosphate aldolase
Class II fructose-1,6-bisphosphate aldolase from Thermus aquaticus in complex with cobalt
 0.24 15.91 0.55 74-211 X-ray 2.30 homo-dimer 3 x CO HHblits 0.27
1rv8.1.A
fructose-1,6-bisphosphate aldolase
Class II fructose-1,6-bisphosphate aldolase from Thermus aquaticus in complex with cobalt
 0.24 15.91 0.55 74-211 X-ray 2.30 homo-dimer 3 x CO HHblits 0.27
7etx.1.A
Tryptophan biosynthesis protein TrpCF
Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (TrpC) from corynebacterium glutamicum
 0.29 11.19 0.56 83-226 X-ray 2.10 homo-dimer HHblits 0.26
7ety.1.A
Tryptophan biosynthesis protein TrpCF
Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpC) from Corynebacterium glutamicum in complex with reduced 1-(O-carboxyphenylamino)-1-deoxyribulose 5-phosphate (rCdRP)
 0.29 11.19 0.56 83-226 X-ray 2.21 homo-dimer 4 x 137 HHblits 0.26
6b8s.1.A
Dihydroorotate dehydrogenase (quinone)
Crystal Structure of Dihydroorotate Dehydrogenase from Helicobacter pylori with bound FMN
 0.26 13.85 0.55 98-227 X-ray 2.25 monomer 1 x FMN HHblits 0.28
3q58.1.A
N-acetylmannosamine-6-phosphate 2-epimerase
Structure of N-acetylmannosamine-6-Phosphate Epimerase from Salmonella enterica
 0.29 15.91 0.55 80-216 X-ray 1.80 homo-dimer 1 x BTB HHblits 0.27
3q58.1.B
N-acetylmannosamine-6-phosphate 2-epimerase
Structure of N-acetylmannosamine-6-Phosphate Epimerase from Salmonella enterica
 0.30 15.91 0.55 80-216 X-ray 1.80 homo-dimer 1 x BTB HHblits 0.27
4y96.1.A
Triosephosphate Isomerase
Crystal structure of Triosephosphate Isomerase from Gemmata obscuriglobus
 0.21 12.12 0.55 90-221 X-ray 1.58 homo-dimer 2 x CA HHblits 0.27
6vva.1.A
N-acetylmannosamine-6-phosphate 2-epimerase
N-Acetylmannosamine-6-phosphate 2-epimerase from Staphylococcus aureus (strain MRSA USA300)
 0.27 10.61 0.55 88-227 X-ray 1.84 homo-dimer HHblits 0.27
8jgc.1.A
'LOV domain-containing protein,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase'
Cryo-EM structure of Mi3 fused with LOV2
 0.24 14.84 0.54 89-232 EM 0.00 monomer HHblits 0.29
5zkn.1.A
Putative N-acetylmannosamine-6-phosphate 2-epimerase
Structure of N-acetylmannosamine-6-phosphate 2-epimerase from Fusobacterium nucleatum
 0.26 14.62 0.55 78-213 X-ray 2.21 homo-dimer HHblits 0.28
1yxy.1.A
Putative N-acetylmannosamine-6-phosphate 2-epimerase
Crystal Structure of putative N-acetylmannosamine-6-P epimerase from Streptococcus pyogenes (APC29713) Structural genomics, MCSG
 0.26 14.50 0.55 79-216 X-ray 1.60 monomer HHblits 0.27
3gak.1.A
Fructose-bisphosphate aldolase
Structure of Giardia fructose-1,6-biphosphate aldolase
 0.24 13.74 0.55 74-211 X-ray 2.90 homo-dimer 2 x ZN HHblits 0.27
3uwv.1.A
Triosephosphate isomerase
Crystal structure of Staphylococcus Aureus triosephosphate isomerase complexed with 2-phosphoglyceric acid
 0.22 13.64 0.55 91-222 X-ray 2.07 homo-dimer 2 x 2PG HHblits 0.26
3uwu.1.A
Triosephosphate isomerase
Crystal structure of Staphylococcus Aureus triosephosphate isomerase complexed with glycerol-3-phosphate
 0.22 13.64 0.55 91-222 X-ray 2.15 homo-dimer 2 x G3P HHblits 0.26
3gvg.1.A
Triosephosphate isomerase
Crystal structure of Triosephosphate isomerase from Mycobacterium tuberculosis
 0.24 12.88 0.55 90-221 X-ray 1.55 homo-dimer HHblits 0.26
1yya.1.A
triosephosphate isomerase
Crystal structure of TT0473, putative Triosephosphate Isomerase from Thermus thermophilus HB8
 0.22 13.85 0.55 90-219 X-ray 1.60 homo-dimer HHblits 0.27
7sge.1.A
Josiah GPCysR4-I53-50A - nanoparticle component
I53-50 nanoparticle core reconstructed from GPC-I53-50NP by focused refinement
 0.29 13.95 0.54 89-232 EM 0.00 hetero-1-1-mer HHblits 0.28
2btm.1.A
PROTEIN (TRIOSEPHOSPHATE ISOMERASE)
DOES THE HIS12-LYS13 PAIR PLAY A ROLE IN THE ADAPTATION OF THERMOPHILIC TIMS TO HIGH TEMPERATURES?
 0.23 16.15 0.55 91-221 X-ray 2.40 homo-dimer 2 x PGA HHblits 0.27
7mcc.1.A
AI-designed TIM-barrel F2C
Crystal structure of an AI-designed TIM-barrel F2C
 0.23 26.23 0.51 88-225 X-ray 1.46 monomer HHblits 0.32
3glc.1.A
Aldolase lsrF
Crystal Structure of E. coli LsrF in complex with Ribose-5-phosphate
 0.28 13.74 0.55 87-231 X-ray 2.50 homo-10-mer 10 x R5P HHblits 0.27
1mzh.1.A
Deoxyribose-phosphate aldolase
QR15, an Aldolase
 0.23 14.17 0.53 89-221 X-ray 2.00 homo-dimer HHblits 0.29
1mzh.1.B
Deoxyribose-phosphate aldolase
QR15, an Aldolase
 0.23 14.17 0.53 89-221 X-ray 2.00 homo-dimer HHblits 0.29
3eb2.1.A
Putative dihydrodipicolinate synthetase
Crystal structure of Dihydrodipicolinate Synthase from Rhodopseudomonas palustris at 2.0A resolution
 0.23 13.64 0.55 74-213 X-ray 2.04 homo-tetramer HHblits 0.26
6u8e.1.A
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, and NAD+. Filament assembly interface reconstruction.
 0.24 19.05 0.53 87-215 EM 0.00 homo-octamer 8 x IMP, 8 x NAD HHblits 0.29
6u8r.1.C
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, and NAD+. Bent (1/4 compressed, 3/4 extended) segment reconstruction.
 0.24 19.05 0.53 87-215 EM 0.00 homo-16-mer 8 x IMP, 8 x NAD, 16 x ATP HHblits 0.29
6u8r.1.D
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, and NAD+. Bent (1/4 compressed, 3/4 extended) segment reconstruction.
 0.24 19.05 0.53 87-215 EM 0.00 homo-16-mer 8 x IMP, 8 x NAD, 16 x ATP HHblits 0.29
6udo.1.A
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament segment reconstruction.
 0.24 19.05 0.53 87-215 EM 0.00 homo-16-mer 8 x IMP, 16 x GTP, 8 x ATP HHblits 0.29
6ua2.1.A
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (2/4 compressed, 2/4 extended) segment reconstruction.
 0.23 19.05 0.53 87-215 EM 0.00 homo-16-mer 8 x GTP, 12 x ATP, 8 x IMP, 8 x NAD HHblits 0.29
6ua2.1.B
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (2/4 compressed, 2/4 extended) segment reconstruction.
 0.23 19.05 0.53 87-215 EM 0.00 homo-16-mer 8 x GTP, 12 x ATP, 8 x IMP, 8 x NAD HHblits 0.29
6ua2.1.C
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (2/4 compressed, 2/4 extended) segment reconstruction.
 0.23 19.05 0.53 87-215 EM 0.00 homo-16-mer 8 x GTP, 12 x ATP, 8 x IMP, 8 x NAD HHblits 0.29
6ua2.1.D
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Bent (2/4 compressed, 2/4 extended) segment reconstruction.
 0.23 19.05 0.53 87-215 EM 0.00 homo-16-mer 8 x GTP, 12 x ATP, 8 x IMP, 8 x NAD HHblits 0.29
6uaj.1.A
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, NAD+, and 2 mM GTP. Free canonical octamer reconstruction.
 0.23 19.05 0.53 87-215 EM 0.00 homo-octamer 16 x GTP, 8 x ATP, 8 x IMP, 8 x NAD HHblits 0.29
6uc2.1.A
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP and 2 mM GTP. Free canonical octamer reconstruction.
 0.22 19.05 0.53 87-215 EM 0.00 homo-octamer 16 x GTP, 8 x ATP HHblits 0.29
6udq.1.B
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament end reconstruction.
 0.24 19.05 0.53 87-215 EM 0.00 homo-12-mer 8 x IMP, 16 x GTP, 8 x ATP HHblits 0.29
6udq.1.C
Inosine-5'-monophosphate dehydrogenase 2
Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Fully compressed filament end reconstruction.
 0.24 19.05 0.53 87-215 EM 0.00 homo-12-mer 8 x IMP, 16 x GTP, 8 x ATP HHblits 0.29
7mjz.1.A
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
The structure of MiaB with pentasulfide bridge
 0.21 9.09 0.55 12-159 X-ray 2.08 monomer 2 x SF4, 1 x PS5 HHblits 0.25
4mz8.2.C
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with an Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound C91
 0.24 18.11 0.53 87-214 X-ray 2.50 homo-tetramer 4 x IMP, 4 x C91 HHblits 0.28
5uqg.2.A
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor p200
 0.24 18.11 0.53 87-214 X-ray 2.03 homo-tetramer 4 x IMP, 4 x 8L4, 4 x K HHblits 0.28
2zrz.1.A
Isopentenyl-diphosphate delta-isomerase
Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase in complex with reduced FMN and DMAPP
 0.25 15.63 0.54 85-213 X-ray 2.90 homo-tetramer 4 x FNR, 4 x DMA, 4 x MG HHblits 0.28
3vkj.1.H
Isopentenyl-diphosphate delta-isomerase
Crystal structure of Sulfolobus shibatae isopentenyl diphosphate isomerase, octameric form
 0.25 15.63 0.54 85-213 X-ray 1.70 homo-octamer 8 x FNR HHblits 0.28
4r7j.1.D
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of Inosine 5'-monophosphate Dehydrogenase with the Internal Deletion Containing CBS Domain from Campylobacter jejuni
 0.25 18.11 0.53 87-214 X-ray 2.12 homo-tetramer 4 x IMP, 4 x K HHblits 0.28
4mz1.3.B
Inosine-5'-monophosphate dehydrogenase
Crystal Structure of the Inosine 5'-monophosphate Dehydrogenase, with a Internal Deletion of CBS Domain from Campylobacter jejuni complexed with inhibitor compound P12
 0.24 18.11 0.53 87-214 X-ray 2.40 homo-tetramer 4 x IMP, 4 x 2F1, 4 x K HHblits 0.28
6i0m.1.A
Inosine-5'-monophosphate dehydrogenase 2
Structure of human IMP dehydrogenase, isoform 2, bound to GDP
 0.24 19.05 0.53 87-215 X-ray 2.57 homo-octamer 8 x 5GP, 24 x GDP HHblits 0.29