MBRole - Home

Welcome to MBRole (Metabolites Biological Role)

MBRole performs overrepresentation (enrichment) analysis of categorical annotations for a set of compounds of interest. These categorical annotations correspond to biological and chemical information available in a number of public databases and software. Current annotations include:

Biological annotations
- Pathways (from KEGG and SMPDB)
- Enzyme interactions (from KEGG)
- Other interactions (from KEGG)
- Diseases (from HMDB)
- Tissue, biofluid and cellular location (from HMDB)
- Pharmacological action (from PubChem)
- Biological role, chemical role and application (from ChEBI and KEGG)
Chemical annotations
- Chemical taxonomy (from HMDB)
- Chemical groups (from Checkmol)

References

If you use Mbrole, please cite the following article:

Chagoyen, M. and Pazos, F. (2011) 'MBRole: enrichment analysis of metabolomic data' Bioinformatics 27: 730-731

Feedback

Did you miss some relevant annotations? Are you interested in adding pre-compiled background sets?... We want to hear from you to improve MBRole. Please write your comments and suggestions to monica.chagoyen/at/cnb.csic.es