| comparative
gene prediction |
|
|
|
|
|
|
|
|
|
|
|
| 4. GENE
PREDICTION IS (EVEN MORE) SEPARATED
FROM |
||||||||||
| SEQUENCE
ALIGNMENT |
||||||||||
| This
approach does not require the
comparison of two homologous
genomic |
||||||||||
| sequencs.
Rather, a query sequence from a target
genome is compared against |
||||||||||
| a collection of
sequence from a second (informant, reference) genome and the |
||||||||||
| results of the
comparison are used to modify the scores of the exons produced |
||||||||||
| by underlying
``ab initio'' gene prediction algorithms. |
||||||||||
| • | twinscan – korf et al., 2001 |
|||||||||
| • | sgp-2 – parra et al., 2003 |
|||||||||