| comparative
gene prediction |
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| 2. GENE
PREDICTION AND SEQUENCE ALIGNMENT ARE |
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| PRODUCED
SIMULTANIOUSLY |
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| given two
homologous genomic sequences, Pair hidden Markov Models for |
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| sequence
alignment, and Generalized HMMs (GHMMs) for gene prediction are |
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| combined into
the so-called Generalized Pair HMMs |
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| • | progen – novichkov et al., 2001 |
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| • | slam – pachter et al, 2001 |
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| • | doublescan – meyer and durbin, 2002 |
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