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Acute promyelocytic leukemia
1 OMIM reference -
7 associated genes
432 connected diseases
No signs/symptoms info
Disease Type of connection
Acute myeloblastic leukemia with maturation
Acute myeloblastic leukemia without maturation
Acute myelomonocytic leukemia
Laron syndrome with immunodeficiency
Precursor B-cell acute lymphoblastic leukemia
Papillary or follicular thyroid carcinoma
Giant cell glioblastoma
Gliosarcoma
Amyotrophic lateral sclerosis
Acute myeloid leukemia with t(8;21)(q22;q22) translocation
Juvenile rheumatoid factor-negative polyarthritis
Oligoarticular juvenile arthritis
Familial pancreatic carcinoma
Essential thrombocythemia
Young adult-onset Parkinsonism
Precursor T-cell acute lymphoblastic leukemia
Rubinstein-Taybi syndrome due to EP300 haploinsufficiency
Dedifferentiated liposarcoma
Well-differentiated liposarcoma
Li-Fraumeni syndrome
Weaver syndrome
Estrogen resistance syndrome
Hereditary breast and ovarian cancer syndrome
Autosomal recessive primary microcephaly
17q11 microdeletion syndrome
Familial thoracic aortic aneurysm and aortic dissection
Distal 22q11.2 microdeletion syndrome
Acute myeloid leukemia
Deafness - lymphedema - leukemia
Monocytopenia with susceptibility to infections
Myelodysplastic syndromes
Retinitis pigmentosa
Adrenocortical carcinoma
B-cell chronic lymphocytic leukemia
Papilloma of choroid plexus
Glucocorticoid resistance
Coffin-Siris syndrome
Autosomal dominant nonsyndromic intellectual deficit
Familial melanoma
Acute myeloid leukemia with t(8;16)(p11;p13) translocation
Rubinstein-Taybi syndrome due to 16p13.3 microdeletion
Rubinstein-Taybi syndrome due to CREBBP mutations
Familial retinoblastoma
Monosomy 13q14
Unilateral retinoblastoma
Follicular lymphoma
Intravascular large B-cell lymphoma
Cornelia de Lange syndrome
Juvenile myelomonocytic leukemia
Behavioral variant of frontotemporal dementia
Progressive non-fluent aphasia
Semantic dementia
Fanconi anemia
Inflammatory myofibroblastic tumor
Acute basophilic leukemia
Anaplastic ependymoma
Autosomal dominant Emery-Dreifuss muscular dystrophy
2q37 microdeletion syndrome
Cowden syndrome
Proteus syndrome
X-linked dominant chondrodysplasia, Chassaing-Lacombe type
Aneurysm - osteoarthritis syndrome
1p36 deletion syndrome
Shprintzen-Goldberg syndrome
Blackfan-Diamond anemia
Budd-Chiari syndrome
Familial thrombocytosis
Myelofibrosis with myeloid metaplasia
Polycythemia vera
Autosomal dominant hyper-IgE syndrome
Familial isolated dilated cardiomyopathy
Familial prostate cancer
Noonan syndrome
Primary mediastinal large B-cell lymphoma
Idiopathic pulmonary fibrosis
Autoimmune lymphoproliferative syndrome
Angelman syndrome
Chronic myeloid leukemia
Familial platelet syndrome with predisposition to acute myelogenous leukemia
Isolated delta-storage pool disease
Seckel syndrome
Acute myeloid leukemia with CEBPA somatic mutations
Ewing sarcoma
Extraskeletal Ewing sarcoma
Inherited acute myeloid leukemia
Peripheral primitive neuroectodermal tumor
Fibronectin glomerulopathy
Short stature due to isolated growth hormone deficiency with X-linked hypogammaglobulinemia
Multiple endocrine neoplasia type 1
46,XY complete gonadal dysgenesis
Primary ciliary dyskinesia
Adult-onset distal myopathy due to VCP mutation
Common variable immunodeficiency
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia
Proximal spinal muscular atrophy type 1
Proximal spinal muscular atrophy type 2
Proximal spinal muscular atrophy type 3
Proximal spinal muscular atrophy type 4
Spastic paraplegia - Paget disease of bone
Alveolar rhabdomyosarcoma
Chronic mucocutaneous candidiasis
46,XY partial gonadal dysgenesis
Huntington disease
Juvenile Huntington disease
Neuroblastoma
Gastrointestinal stromal tumor
Familial rhabdoid tumor
Pseudohypoaldosteronism type 2E
Early-onset autosomal dominant Alzheimer disease
Hereditary cerebral hemorrhage with amyloidosis, Arctic type
Hereditary cerebral hemorrhage with amyloidosis, Dutch type
Hereditary cerebral hemorrhage with amyloidosis, Flemish type
Hereditary cerebral hemorrhage with amyloidosis, Iowa type
Hereditary cerebral hemorrhage with amyloidosis, Italian type
Hereditary cerebral hemorrhage with amyloidosis, Piedmont type
Idiopathic hypereosinophilic syndrome
Loeys-Dietz syndrome type 1
Atypical Werner syndrome
Autosomal codominant severe lipodystrophic laminopathy
Autosomal dominant limb-girdle muscular dystrophy type 1B
Autosomal recessive Emery-Dreifuss muscular dystrophy
Charcot-Marie-Tooth disease type 2B1
Congenital muscular dystrophy due to LMNA mutation
Dilated cardiomyopathy - hypergonadotropic hypogonadism
Familial dilated cardiomyopathy with conduction defect due to LMNA mutation
Familial isolated arrhythmogenic ventricular dysplasia, biventricular form
Familial isolated arrhythmogenic ventricular dysplasia, left dominant form
Familial isolated arrhythmogenic ventricular dysplasia, right dominant form
Familial partial lipodystrophy, Dunnigan type
Familial partial lipodystrophy, Köbberling type
Heart-hand syndrome, Slovenian type
Hutchinson-Gilford progeria syndrome
LMNA-related cardiocutaneous progeria syndrome
Laminopathy type Decaudain-Vigouroux
Left ventricular noncompaction
Lethal restrictive dermopathy
Mandibuloacral dysplasia with type A lipodystrophy
Progeria-associated arthropathy
Autosomal recessive nonsyndromic sensorineural deafness type DFNB
Chudley-McCullough syndrome
Hypocalcemic vitamin D-resistant rickets
Alobar holoprosencephaly
Burkitt lymphoma
Lobar holoprosencephaly
Microform holoprosencephaly
Midline interhemispheric variant of holoprosencephaly
Semilobar holoprosencephaly
Septopreoptic holoprosencephaly
Bohring-Opitz syndrome
Goldmann-Favre syndrome
Hyperinsulinism due to INSR deficiency
Insulin-resistance syndrome type A
Leprechaunism
Rabson-Mendenhall syndrome
Berardinelli-Seip congenital lipodystrophy
Beta-thalassemia - X-linked thrombocytopenia
Congenital erythropoietic porphyria
Primary familial polycythemia
Thrombocytopenia with congenital dyserythropoietic anemia
X-linked dyserythropoetic anemia with abnormal platelets and neutropenia
Intellectual deficit, X-linked, Siderius type
5q35 microduplication syndrome
Beckwith-Wiedemann syndrome due to NSD1 mutation
Charcot-Marie-Tooth disease type 2B2
Sotos syndrome
Branchio-oculo-facial syndrome
Hereditary breast cancer
Hereditary site-specific ovarian cancer syndrome
Melanoma and neural system tumor syndrome
Melanoma-pancreatic cancer syndrome
Primary peritoneal carcinoma
Craniopharyngioma
Desmoid tumor
Ear-patella-short stature syndrome
Hepatocellular carcinoma, childhood-onset
LEOPARD syndrome
Metachondromatosis
Pilomatrixoma
Dyskeratosis congenita
Hoyeraal-Hreidarsson syndrome
Idiopathic aplastic anemia
Renal tubular dysgenesis of genetic origin
Athyreosis
Benign familial chorea
Brain-lung-thyroid syndrome
Laron syndrome
Short stature due to partial GHR deficiency
Thyroid hypoplasia
Wilson disease
12q14 microdeletion syndrome
17p13.3 microduplication syndrome
Distal 17p13.3 microdeletion syndrome
Miller-Dieker syndrome
T-B+ severe combined immunodeficiency due to CD3delta / CD3epsilon / CD3zeta
Distal myopathy, Nonaka type
Sialuria
X-linked intellectual disability, Hedera type
X-linked parkinsonism-spasticity syndrome
ADULT syndrome
Ankyloblepharon - ectodermal defects - cleft lip / palate
Bladder exstrophy
EEC syndrome
Familial multiple nevi flammei
Joubert syndrome with oculorenal defect
Limb-mammary syndrome
Split hand-split foot malformation
Sturge-Weber syndrome
22q11.2 deletion syndrome
Achromatopsia
Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)
Aleukemic mast cell leukemia
Alpha-thalassemia - X-linked intellectual deficit syndrome
Alpha-thalassemia - myelodysplastic syndrome
Bullous diffuse cutaneous mastocytosis
Carpenter-Waziri syndrome
Chudley-Lowry-Hoar syndrome
Classic mast cell leukemia
Cone rod dystrophy
Cutaneous mastocytoma
Granulomatosis with polyangiitis
Holmes-Gang syndrome
Isolated bone marrow mastocytosis
Juberg-Marsidi syndrome
Lymphoadenopathic mastocytosis with eosinophilia
Nodular urticaria pigmentosa
Osteosarcoma
Piebaldism
Plaque-form urticaria pigmentosa
Primary ciliary dyskinesia - retinitis pigmentosa
Pseudoxanthomatous diffuse cutaneous mastocytosis
Smith-Fineman-Myers syndrome
Smouldering systemic mastocytosis
Systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease
Telangiectasia macularis eruptiva perstans
Typical urticaria pigmentosa
X-linked non-syndromic intellectual deficit
17q11.2 microduplication syndrome
46,XX gonadal dysgenesis
Acrodysostosis
Acrodysostosis with multiple hormone resistance
Acute megakaryoblastic leukemia without Down syndrome
Acute necrotizing encephalopathy of childhood
Adult-onset foveomacular vitelliform dystrophy
Alopecia universalis
Amyotrophic lateral sclerosis-parkinsonism-dementia complex
Antley-Bixler syndrome
Apert syndrome
Atelosteogenesis type I
Atelosteogenesis type III
Athabaskan brainstem dysgenesis syndrome
Atrichia with papular lesions
Atypical glycine encephalopathy
Atypical hemolytic uremic syndrome with H factor anomaly
Autosomal agammaglobulinemia
Autosomal dominant Charcot-Marie-Tooth disease type 2F
Autosomal dominant Charcot-Marie-Tooth disease type 2M
Autosomal dominant Charcot-Marie-Tooth disease type 2N
Autosomal dominant Larsen syndrome
Autosomal dominant centronuclear myopathy
Autosomal dominant hypohidrotic ectodermal dysplasia
Autosomal dominant intermediate Charcot-Marie-Tooth disease type B
Autosomal dominant secondary polycythemia
Autosomal recessive cerebellar ataxia - epilepsy - intellectual deficit
Autosomal recessive limb-girdle muscular dystrophy type 2H
Autosomal recessive nonsyndromic intellectual deficit
BAP1-related tumor predisposition syndrome
Bardet-Biedl syndrome
Boomerang dysplasia
Bosley-Salih-Alorainy syndrome
CLN11 disease
Cardiomyopathy - hypotonia - lactic acidosis
Carney complex
Chronic intestinal pseudoobstruction
Cleidocranial dysplasia
Combined oxidative phosphorylation defect type 4
Complete androgen insensitivity syndrome
Congenital fibrosis of extraocular muscles
Congenital short bowel syndrome
Congenital valvular dysplasia
Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutation
Crouzon disease
Cutis gyrata - acanthosis nigricans - craniosynostosis
DPM1-CDG
Dense deposit disease
Distal hereditary motor neuropathy type 2
Distal myopathy with posterior leg and anterior hand involvement
Dubowitz syndrome
Ehlers-Danlos syndrome with periventricular heterotopia
Erythrocyte galactose epimerase deficiency
Extraskeletal myxoid chondrosarcoma
FGFR2-related bent bone dysplasia
Familial acute necrotizing encephalopathy
Familial advanced sleep-phase syndrome
Familial atrial myxoma
Familial capillary hemangioma
Familial congenital mirror movements
Familial drusen
Familial hypospadias
Familial infantile bilateral striatal necrosis
Familial multinodular goiter
Familial partial lipodystrophy associated with PPARG mutations
Familial partial lipodystrophy due to AKT2 mutations
Familial scaphocephaly syndrome, McGillivray type
Familial steroid-resistant nephrotic syndrome with sensorineural deafness
Fetal akinesia-cerebral and retinal hemorrhage syndrome
Frontometaphyseal dysplasia
Frontotemporal dementia with motor neuron disease
Fuchs endothelial corneal dystrophy
Generalized congenital lipodystrophy with myopathy
Generalized galactose epimerase deficiency
Glycogen storage disease due to liver phosphorylase kinase deficiency
Griscelli disease type 2
Hereditary motor and sensory neuropathy, Okinawa type
Hereditary thrombophilia due to congenital protein S deficiency
Hypoinsulinemic hypoglycemia and body hemihypertrophy
Immunodeficiency with factor H anomaly
Immunoglobulin-mediated membranoproliferative glomerulonephritis
Infantile glycine encephalopathy
Infantile hypertrophic cardiomyopathy due to MRPL44 deficiency
Infantile-onset mesial temporal lobe epilepsy with severe cognitive regression
Intellectual disability-feeding difficulties-developmental delay-microcephaly syndrome
Isolated ATP synthase deficiency
Isolated adermatoglyphia
Isolated growth hormone deficiency type IA
Isolated growth hormone deficiency type IB
Isolated growth hormone deficiency type II
Jackson-Weiss syndrome
Juvenile autosomal recessive medullary cystic kidney disease
Kennedy disease
Kostmann syndrome
LAMB-2-related infantile-onset nephrotic syndrome
Lacrimo-auriculo-dento-digital syndrome
Machado-Joseph disease type 1
Machado-Joseph disease type 2
Machado-Joseph disease type 3
Marie Unna hereditary hypotrichosis
Metaphyseal dysplasia - maxillary hypoplasia - brachydacty
Microcephaly - lymphedema - chorioretinopathy
Multiple paragangliomas associated with polycythemia
Muscle filaminopathy
Neonatal glycine encephalopathy
Nestor-Guillermo progeria syndrome
Neurofibromatosis type 1 due to NF1mutation or intragenic deletion
Neurological conditions associated with aminoacylase 1 deficiency
Obesity due to melanocortin 4 receptor deficiency
Oculopharyngeal muscular dystrophy
Osteodysplasty, Melnick-Needles type
Otopalatodigital syndrome type 1
Otopalatodigital syndrome type 2
Ovarian hyperstimulation syndrome
Ovarian malignant Sertoli-Leydig cell tumor
Pallister-Hall syndrome
Partial androgen insensitivity syndrome
Periventricular nodular heterotopia
Pfeiffer syndrome type 1
Pfeiffer syndrome type 2
Pfeiffer syndrome type 3
Pierson syndrome
Pilocytic astrocytoma
Pitt-Hopkins syndrome
Pleuropulmonary blastoma family tumor susceptibility syndrome
Primary pigmented nodular adrenocortical disease
Primary sclerosing cholangitis
Proximal myotonic myopathy
Pyruvate carboxylase deficiency, benign type
Pyruvate carboxylase deficiency, infantile type
Pyruvate carboxylase deficiency, severe neonatal type
SHORT syndrome
Saethre-Chotzen syndrome
Short stature due to growth hormone qualitative anomaly
Spastic paraplegia-optic atrophy-neuropathy syndrome
Spinocerebellar ataxia type 26
Spinocerebellar ataxia type 36
Spondylocarpotarsal synostosis
Spondyloenchondrodysplasia
Sporadic pheochromocytoma
Sporadic secreting paraganglioma
Synaptic congenital myasthenic syndromes
Systemic-onset juvenile idiopathic arthritis
T-B+ severe combined immunodeficiency due to JAK3 deficiency
Terminal osseous dysplasia - pigmentary defects
Translocation renal cell carcinoma
Uveal coloboma - cleft lip and palate - intellectual deficit
Watson syndrome
Werner syndrome
Wolf-Hirschhorn syndrome
X-linked Opitz G / BBB syndrome
Mendelian susceptibility to mycobacterial diseases due to partial STAT1 deficiency
Peripheral resistance to thyroid hormones
Susceptibility to viral and mycobacterial infections
16q24.3 microdeletion syndrome
Achondrogenesis type 1A
Autosomal dominant nonsyndromic sensorineural deafness type DFNA
Cerebellar ataxia-deafness-narcolepsy syndrome
External auditory canal aplasia / hypoplasia
Familial multiple meningioma
Glycogen storage disease due to muscle phosphorylase kinase deficiency
KBG syndrome
Muscular dystrophy, Selcen type
Paternal uniparental disomy of chromosome 6
Syndromic multisystem autoimmune disease due to Itch deficiency
Transient neonatal diabetes mellitus
Williams syndrome
ALK-positive anaplastic large cell lymphoma
ALK-positive large B-cell lymphoma
Baraitser-Winter syndrome
Developmental malformations - deafness - dystonia
Spinocerebellar ataxia type 1
Autoinflammation and PLCG2-associated antibody deficiency and immune dysregulation
Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis
Bilateral striopallidodentate calcinosis
Cataract-microcornea syndrome
Cerulean cataract
Chronic myelomonocytic leukemia
Hereditary nonpolyposis colon cancer
Immunodeficiency due to CD25 deficiency
Infantile myofibromatosis
Marfan syndrome type 2
Mucocutaneous venous malformations
Multiple keratoacanthoma, Ferguson-Smith type
Myeloid neoplasm associated with PDGFRA rearrangement
Myeloid neoplasm associated with PDGFRB rearrangement
Noonan syndrome-like disorder with juvenile myelomonocytic leukemia
Omenn syndrome
PLCG2-associated antibody deficiency and immune dysregulation
Peters anomaly
Pulverulent cataract
T-B+ severe combined immunodeficiency due to IL-7Ralpha deficiency
Unclassified chronic myeloproliferative disease
WHIM syndrome
Glycogen storage disease due to LAMP-2 deficiency
17q23.1q23.2 microdeletion syndrome
Synonym(s):
- Acute myeloblastic leukemia type 3
- Acute myeloid leukemia with t(15;17)(q22;q12);(PML/RARalpha) and variants

Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease

Classification (ICD10):
- Neoplasms -

Epidemiological data:
(no data available)
External references:
1 OMIM reference -
1 MeSH reference: D015473

No signs/symptoms info available.