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4 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 4
14 OMIM references -
13 associated genes
No signs/symptoms info
Severe congenital nemaline myopathy
Young adult-onset Parkinsonism

ACTA1 EIF4G1
KLHL40 GBA
KLHL41 GIGYF2
NEB HTRA2
LRRK2
NR4A2
PACRG
PARK2
PARK7
PINK1
SNCA
UCHL1
VPS35


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
ACTA1
ACTA1
ACTA1
ACTA1
(0.7)
(0.63)
(0.63)
(0.56)
HTRA2
LRRK2
PARK2
SNCA



Citations in the biomedical literature:


Severe congenital nemaline myopathy
ACTA1 KLHL40 KLHL41 NEB
Young adult-onset Parkinsonism
EIF4G1 GBA GIGYF2 HTRA2 LRRK2 NR4A2
PACRG PARK2 PARK7 PINK1 SNCA UCHL1
VPS35



Severe congenital nemaline myopathy
Young adult-onset Parkinsonism

Synonym(s):
(no synonyms)

Synonym(s):
- Early-onset Parkinson disease
- Familial Parkinson disease
- Hereditary Parkinson disease
- Young-onset Parkinson disease

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Diseases of the nervous system -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: neonatal/infancy
Average age of death: child / adolescent
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: elderly
Type of inheritance: autosomal dominant

External references:
No OMIM references
No MeSH references
External references:
14 OMIM references -
No MeSH references

No signs/symptoms info available.