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1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 1
7 OMIM references -
12 associated genes
No signs/symptoms info
Severe combined immunodeficiency due to LCK deficiency
Hereditary nonpolyposis colon cancer

LCK BMPR1A
EPCAM
KRAS
LRRFIP2
MLH1
MLH3
MSH2
MSH6
PIK3CA
PMS1
PMS2
TGFBR2


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
LCK
(0.89)
PIK3CA



Citations in the biomedical literature:


Severe combined immunodeficiency due to LCK deficiency
LCK
Hereditary nonpolyposis colon cancer
BMPR1A EPCAM KRAS LRRFIP2 MLH1 MLH3
MSH2 MSH6 PIK3CA PMS1 PMS2 TGFBR2



Severe combined immunodeficiency due to LCK deficiency
Hereditary nonpolyposis colon cancer

Synonym(s):
- SCID due to LCK deficiency
- SCID due to lymphocyte-specific protein tyrosine kinase deficiency
- Severe combined immunodeficiency due to lymphocyte-specific protein tyrosine kinase deficiency

Synonym(s):
- Familial nonpolyposis colon cancer
- Familial nonpolyposis colorectal cancer
- HNPCC
- Hereditary nonpolyposis colorectal cancer
- Lynch syndrome

Classification (Orphanet):
- Rare genetic disease
- Rare immune disease
Classification (Orphanet):
(no data available)

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: -
Type of inheritance: autosomal dominant

External references:
No OMIM references
No MeSH references
External references:
7 OMIM references -
1 MeSH reference: D003123

No signs/symptoms info available.