Cytoscape Web
Click node...


6 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 7
14 OMIM references -
13 associated genes
No signs/symptoms info
Semantic dementia
Young adult-onset Parkinsonism

C9ORF72 EIF4G1
CHMP2B GBA
GRN GIGYF2
MAPT HTRA2
PSEN1 LRRK2
VCP NR4A2
PACRG
PARK2
PARK7
PINK1
SNCA
UCHL1
VPS35


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
MAPT
MAPT
MAPT
VCP
PSEN1
VCP
VCP
(0.89)
(0.88)
(0.82)
(0.73)
(0.63)
(0.63)
(0.63)
SNCA
LRRK2
PARK2
PARK2
HTRA2
GIGYF2
PACRG



Citations in the biomedical literature:


Semantic dementia
C9ORF72 CHMP2B GRN MAPT PSEN1 VCP

Young adult-onset Parkinsonism
EIF4G1 GBA GIGYF2 HTRA2 LRRK2 NR4A2
PACRG PARK2 PARK7 PINK1 SNCA UCHL1
VPS35



Semantic dementia
Young adult-onset Parkinsonism

Synonym(s):
- Semantic primary progressive aphasia
- Semantic variant PPA

Synonym(s):
- Early-onset Parkinson disease
- Familial Parkinson disease
- Hereditary Parkinson disease
- Young-onset Parkinson disease

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Diseases of the nervous system -

Epidemiological data:
Class of prevalence: -
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: elderly
Type of inheritance: autosomal dominant

External references:
No OMIM references
No MeSH references
External references:
14 OMIM references -
No MeSH references

No signs/symptoms info available.