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6 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
8 OMIM references -
6 associated genes
12 signs/symptoms
Semantic dementia
Familial melanoma

C9ORF72 CDK4
CHMP2B CDKN2A
GRN CDKN2B
MAPT CDKN2D
PSEN1 MC1R
VCP TERT


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
VCP
(0.63)
CDK4



Citations in the biomedical literature:


Semantic dementia
C9ORF72 CHMP2B GRN MAPT PSEN1 VCP

Familial melanoma
CDK4 CDKN2A CDKN2B CDKN2D MC1R TERT



Semantic dementia
Familial melanoma

Synonym(s):
- Semantic primary progressive aphasia
- Semantic variant PPA

Synonym(s):
(no synonyms)

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare eye disease
- Rare genetic disease
- Rare oncologic disease
- Rare skin disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: -
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: unknown
Average age onset: variable
Average age of death: -
Type of inheritance: autosomal dominant

External references:
No OMIM references
No MeSH references
External references:
8 OMIM references -
No MeSH references

Familial melanoma

Very frequent
- Capillary hemangioma / nevus / naevus flammeus / port-wine stain
- Melanoma

Frequent
- Anomalies of the lymphatic system
- Dry / squaly skin / exfoliation
- Excessive freckling
- Hair and scalp anomalies

Occasional
- Autosomal dominant inheritance
- Breast neoplasm / tumor / carcinoma / cancer
- Estomach / gastric neoplasm / tumor / carcinoma / cancer
- Extrapyramidal syndrome
- Pancreatic / pancreas neoplasm / tumor / carcinoma / cancer
- Retinopathy


Semantic dementia

(no data available)