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6 associated genes
No signs/symptoms info
COMMON GENES: 1
PROTEIN INTERACTIONS: 5
16 OMIM references -
4 associated genes
No signs/symptoms info
Semantic dementia
Early-onset autosomal dominant Alzheimer disease

C9ORF72 APP
CHMP2B PSEN1
GRN PSEN2
MAPT SORL1
PSEN1
VCP


COMMON
GENES
PSEN1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
PSEN1
PSEN1
MAPT
C9ORF72
MAPT
(0.88)
(0.87)
(0.79)
(0.56)
(0.55)
APP
PSEN2
APP
APP
PSEN1



Citations in the biomedical literature:


Semantic dementia
C9ORF72 CHMP2B GRN MAPT PSEN1 VCP

Early-onset autosomal dominant Alzheimer disease
APP PSEN2 SORL1



Semantic dementia
Early-onset autosomal dominant Alzheimer disease

Synonym(s):
- Semantic primary progressive aphasia
- Semantic variant PPA

Synonym(s):
- EOFAD
- Early-onset familial autosomal dominant Alzheimer disease
- Familial Alzheimer disease

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Diseases of the nervous system -

Epidemiological data:
Class of prevalence: -
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: adult
Type of inheritance: autosomal dominant

External references:
No OMIM references
No MeSH references
External references:
16 OMIM references -
No MeSH references

No signs/symptoms info available.