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2 associated genes
No signs/symptoms info
COMMON GENES: 1
PROTEIN INTERACTIONS: 2
14 associated genes
No signs/symptoms info
Radial hemimelia, bilateral
Midline interhemispheric variant of holoprosencephaly

LMBR1 CDON
SHH DISP1
DLL1
FGF8
FOXH1
GAS1
GLI2
NODAL
PTCH1
SHH
SIX3
TDGF1
TGIF1
ZIC2


COMMON
GENES
SHH


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
SHH
SHH
(0.59)
(0.55)
PTCH1
GAS1



Citations in the biomedical literature:


Radial hemimelia, bilateral
LMBR1 SHH
Midline interhemispheric variant of holoprosencephaly
CDON DISP1 DLL1 FGF8 FOXH1 GAS1
GLI2 NODAL PTCH1 SIX3 TDGF1
TGIF1 ZIC2



Radial hemimelia, bilateral
Midline interhemispheric variant of holoprosencephaly

Synonym(s):
- Radial longitidinal meromelia, bilateral

Synonym(s):
- MIH
- MIH type HPE
- MIHF
- MIHV
- Middle interhemispheric fusion variant
- Middle interhemispheric variant of holoprosencephaly
- Syntelencephaly

Classification (Orphanet):
- Rare bone disease
- Rare developmental defect during embryogenesis
- Rare genetic disease
Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -
Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -

Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: multigenic/multifactorial

External references:
No OMIM references
No MeSH references
External references:
No OMIM references
No MeSH references

No signs/symptoms info available.