Cytoscape Web
Click node...


5 OMIM references -
8 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
6 OMIM references -
10 associated genes
8 signs/symptoms
Primary biliary cirrhosis
Oligodontia

IL12A AXIN2
IL12RB1 EDA
IRF5 EDARADD
MMEL1 FGFR1
POU2AF1 IRF6
SPIB LTBP3
TNFSF15 MSX1
TNPO3 PAX9
TGFA
WNT10A


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
IRF5
(0.72)
IRF6



Citations in the biomedical literature:


Primary biliary cirrhosis
IL12A IL12RB1 IRF5 MMEL1 POU2AF1 SPIB
TNFSF15 TNPO3
Oligodontia
AXIN2 EDA EDARADD FGFR1 IRF6 LTBP3
MSX1 PAX9 TGFA WNT10A



Primary biliary cirrhosis
Oligodontia

Synonym(s):
- Hanot syndrome

Synonym(s):
- Selective tooth agenesis

Classification (Orphanet):
- Rare hepatic disease
Classification (Orphanet):
- Rare genetic disease
- Rare odontologic disease

Classification (ICD10):
- Diseases of the digestive system -
Classification (ICD10):
- Diseases of the digestive system -

Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: unknown
Average age onset: childhood
Average age of death: normal
Type of inheritance: autosomal dominant

External references:
5 OMIM references -
No MeSH references
External references:
6 OMIM references -
No MeSH references

Oligodontia

Very frequent
- Anodontia / oligodontia / hypodontia
- Complete / partial microdontia
- Face / facial anomalies
- Hypoplastic mandibula / partial absence of the mandibula
- Tooth shape anomaly

Frequent
- Autosomal dominant inheritance
- Autosomal recessive inheritance
- X-linked recessive inheritance



Primary biliary cirrhosis

(no data available)