Cytoscape Web
Click node...


5 OMIM references -
8 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
9 associated genes
8 signs/symptoms
Primary biliary cirrhosis
Juvenile rheumatoid factor-negative polyarthritis

IL12A ANKRD55
IL12RB1 CD247
IRF5 FAS
MMEL1 IL2RA
POU2AF1 IL2RB
SPIB PTPN2
TNFSF15 PTPN22
TNPO3 STAT4
TYK2


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
IL12RB1
(0.62)
STAT4



Citations in the biomedical literature:


Primary biliary cirrhosis
IL12A IL12RB1 IRF5 MMEL1 POU2AF1 SPIB
TNFSF15 TNPO3
Juvenile rheumatoid factor-negative polyarthritis
ANKRD55 CD247 FAS IL2RA IL2RB PTPN2
PTPN22 STAT4 TYK2



Primary biliary cirrhosis
Juvenile rheumatoid factor-negative polyarthritis

Synonym(s):
- Hanot syndrome

Synonym(s):
- Polyarthritis without rheumatoid factor

Classification (Orphanet):
- Rare hepatic disease
Classification (Orphanet):
- Rare respiratory disease

Classification (ICD10):
- Diseases of the digestive system -
Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -

Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: -
Average age of death: normal
Type of inheritance: multigenic/multifactorial

External references:
5 OMIM references -
No MeSH references
External references:
No OMIM references
No MeSH references

Juvenile rheumatoid factor-negative polyarthritis

Very frequent
- Abnormal dentition / dental position / implantation / unerupted / dental ankylosis
- Arthritis / synovitis / synovial proliferation
- Articular / joint pain / arthralgia
- Autoimmunity / autoimmune reaction / autoantibodies
- Biological inflammatory syndrome / increased erythrocyte sedimentation rate / CRP
- Hydrarthrosis / articular / joint effusion
- Joint / articular deformation
- Restricted joint mobility / joint stiffness / ankylosis



Primary biliary cirrhosis

(no data available)