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4 associated genes
No signs/symptoms info
COMMON GENES: 2
PROTEIN INTERACTIONS: 1
9 associated genes
8 signs/symptoms
Pediatric systemic lupus erythematosus
Juvenile rheumatoid factor-negative polyarthritis

IRAK1 ANKRD55
PTPN22 CD247
SPP1 FAS
STAT4 IL2RA
IL2RB
PTPN2
PTPN22
STAT4
TYK2


COMMON
GENES
PTPN22
STAT4


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
PTPN22
(0.75)
CD247



Citations in the biomedical literature:


Pediatric systemic lupus erythematosus
IRAK1 PTPN22 SPP1 STAT4
Juvenile rheumatoid factor-negative polyarthritis
ANKRD55 CD247 FAS IL2RA IL2RB PTPN2
TYK2



Pediatric systemic lupus erythematosus
Juvenile rheumatoid factor-negative polyarthritis

Synonym(s):
- SLE, pediatric onset

Synonym(s):
- Polyarthritis without rheumatoid factor

Classification (Orphanet):
- Rare neurologic disease
- Rare renal disease
- Rare respiratory disease
- Rare systemic or rheumatologic disease
Classification (Orphanet):
- Rare respiratory disease

Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -
Classification (ICD10):
- Diseases of the musculoskeletal system and connective tissue -

Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: -
Average age of death: normal
Type of inheritance: multigenic/multifactorial

External references:
No OMIM references
No MeSH references
External references:
No OMIM references
No MeSH references

Juvenile rheumatoid factor-negative polyarthritis

Very frequent
- Abnormal dentition / dental position / implantation / unerupted / dental ankylosis
- Arthritis / synovitis / synovial proliferation
- Articular / joint pain / arthralgia
- Autoimmunity / autoimmune reaction / autoantibodies
- Biological inflammatory syndrome / increased erythrocyte sedimentation rate / CRP
- Hydrarthrosis / articular / joint effusion
- Joint / articular deformation
- Restricted joint mobility / joint stiffness / ankylosis



Pediatric systemic lupus erythematosus

(no data available)