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13 OMIM references -
10 associated genes
No signs/symptoms info
COMMON GENES: 4
PROTEIN INTERACTIONS: 11
3 OMIM references -
8 associated genes
9 signs/symptoms
Nuclear cataract
Cataract-microcornea syndrome

CRYAA CRYAA
CRYBB1 CRYBA4
CRYBB2 CRYBB1
CRYBB3 CRYBB2
CRYGD CRYGC
FYCO1 CRYGD
GJA3 GJA8
MIP MAF
NHS
WFS1


COMMON
GENES
CRYAA
CRYBB1
CRYBB2
CRYGD


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
CRYAA
CRYAA
CRYBB2
CRYAA
MIP
MIP
MIP
CRYBB1
CRYBB2
CRYGD
MIP
(0.89)
(0.88)
(0.88)
(0.78)
(0.77)
(0.65)
(0.65)
(0.63)
(0.63)
(0.63)
(0.52)
CRYGC
CRYBB2
CRYGC
CRYGD
CRYAA
CRYBB2
CRYGC
CRYBA4
CRYBA4
CRYGC
GJA8



Citations in the biomedical literature:


Nuclear cataract
CRYAA CRYBB1 CRYBB2 CRYBB3 CRYGD FYCO1
GJA3 MIP NHS WFS1
Cataract-microcornea syndrome
CRYBA4 CRYGC
GJA8 MAF



Nuclear cataract
Cataract-microcornea syndrome

Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare eye disease
- Rare genetic disease
Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare eye disease
- Rare genetic disease

Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -
Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -

Epidemiological data:
Class of prevalence: -
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: autosomal dominant

External references:
13 OMIM references -
No MeSH references
External references:
3 OMIM references -
1 MeSH reference: C538287

Cataract-microcornea syndrome

Very frequent
- Autosomal dominant inheritance
- Autosomal recessive inheritance
- Cataract / lens opacification
- Microcornea

Frequent
- Myopia

Occasional
- Coloboma of iris
- Corneal clouding / opacity / vascularisation
- Corneal dystrophy
- Nystagmus


Nuclear cataract

(no data available)