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5 OMIM references -
4 associated genes
11 signs/symptoms
PROTEIN INTERACTIONS: 3
3 associated genes
4 signs/symptoms
Nephroblastoma
Well-differentiated liposarcoma

DIS3L2 CDK4
H19 HMGA2
POU6F2 MDM2
WT1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
H19
H19
WT1
(0.63)
(0.63)
(0.63)
CDK4
MDM2
MDM2



Citations in the biomedical literature:


Nephroblastoma
DIS3L2 H19 POU6F2 WT1
Well-differentiated liposarcoma
CDK4 HMGA2 MDM2



Nephroblastoma
Well-differentiated liposarcoma

Synonym(s):
- Renal embryonic tumor
- Wilms tumor

Synonym(s):
- ALT
- Atypical lipoma
- Atypical lipomatous tumor
- WDLS

Classification (Orphanet):
- Rare genetic disease
Classification (Orphanet):
- Rare oncologic disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: childhood
Average age of death: any age
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: adult
Type of inheritance: sporadic

External references:
5 OMIM references -
1 MeSH reference: D009396
External references:
No OMIM references
No MeSH references

Nephroblastoma
Well-differentiated liposarcoma

Very frequent
- Acute abdominal pain / colic
- Kidney / renal neoplasm / tumor / carcinoma / cancer
- Neoplasms / tumors

Occasional
- Aniridia / iris hypoplasia
- Chronic arterial hypertension
- Fever / chilling
- Hematuria / microhematuria
- Hepatic / liver neoplasm / tumor / carcinoma / cancer
- Lung / bronchopulmonary neoplasm / tumor / carcinoma / cancer
- Lymphadenopathy / polyadenopathies
- Weight loss / loss of appetite / break in weight curve / general health alteration


Very frequent
- Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma
- Subcutaneous nodules / lipomas / tumefaction / swelling

Occasional
- Functional anomalies of the kidney and the urinary tract
- Intestinal transit disorder