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5 OMIM references -
4 associated genes
11 signs/symptoms
PROTEIN INTERACTIONS: 4
1 OMIM reference -
20 associated genes
No signs/symptoms info
Nephroblastoma
Precursor B-cell acute lymphoblastic leukemia

DIS3L2 ABL1
H19 AFF1
POU6F2 AUTS2
WT1 BCR
CDKN2A
ETV6
FLT3
FOXP1
GATA3
HLF
IGH
IKZF1
KMT2A
PAX5
PBX1
PDGFRA
PIP4K2A
RUNX1
TCF3
TP53


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
WT1
H19
H19
H19
(0.86)
(0.63)
(0.63)
(0.63)
TP53
CDKN2A
TCF3
TP53



Citations in the biomedical literature:


Nephroblastoma
DIS3L2 H19 POU6F2 WT1
Precursor B-cell acute lymphoblastic leukemia
ABL1 AFF1 AUTS2 BCR CDKN2A ETV6
FLT3 FOXP1 GATA3 HLF IGH IKZF1
KMT2A PAX5 PBX1 PDGFRA PIP4K2A RUNX1
TCF3 TP53



Nephroblastoma
Precursor B-cell acute lymphoblastic leukemia

Synonym(s):
- Renal embryonic tumor
- Wilms tumor

Synonym(s):
- B-ALL
- Precursor B-cell acute lymphoblastic leukemia/lymphoma
- Precursor B-cell acute lymphocytic leukemia
- Precursor B-cell acute lymphocytic leukemia/lymphoma

Classification (Orphanet):
- Rare genetic disease
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: childhood
Average age of death: any age
Type of inheritance: autosomal dominant
Epidemiological data:
(no data available)

External references:
5 OMIM references -
1 MeSH reference: D009396
External references:
1 OMIM reference -
No MeSH references

Nephroblastoma

Very frequent
- Acute abdominal pain / colic
- Kidney / renal neoplasm / tumor / carcinoma / cancer
- Neoplasms / tumors

Occasional
- Aniridia / iris hypoplasia
- Chronic arterial hypertension
- Fever / chilling
- Hematuria / microhematuria
- Hepatic / liver neoplasm / tumor / carcinoma / cancer
- Lung / bronchopulmonary neoplasm / tumor / carcinoma / cancer
- Lymphadenopathy / polyadenopathies
- Weight loss / loss of appetite / break in weight curve / general health alteration


Precursor B-cell acute lymphoblastic leukemia

(no data available)