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5 OMIM references -
4 associated genes
11 signs/symptoms
PROTEIN INTERACTIONS: 4
5 OMIM references -
8 associated genes
No signs/symptoms info
Nephroblastoma
Familial pancreatic carcinoma

DIS3L2 BRCA1
H19 BRCA2
POU6F2 CDKN2A
WT1 KRAS
MANF
PALB2
SMAD4
TP53


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
WT1
H19
H19
H19
(0.86)
(0.65)
(0.63)
(0.63)
TP53
BRCA1
CDKN2A
TP53



Citations in the biomedical literature:


Nephroblastoma
DIS3L2 H19 POU6F2 WT1
Familial pancreatic carcinoma
BRCA1 BRCA2 CDKN2A KRAS MANF PALB2
SMAD4 TP53



Nephroblastoma
Familial pancreatic carcinoma

Synonym(s):
- Renal embryonic tumor
- Wilms tumor

Synonym(s):
- Familial pancreatic cancer

Classification (Orphanet):
- Rare genetic disease
Classification (Orphanet):
- Rare gastroenterologic disease
- Rare genetic disease
- Rare oncologic disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: childhood
Average age of death: any age
Type of inheritance: autosomal dominant
Epidemiological data:
(no data available)

External references:
5 OMIM references -
1 MeSH reference: D009396
External references:
5 OMIM references -
1 MeSH reference: C535837

Nephroblastoma

Very frequent
- Acute abdominal pain / colic
- Kidney / renal neoplasm / tumor / carcinoma / cancer
- Neoplasms / tumors

Occasional
- Aniridia / iris hypoplasia
- Chronic arterial hypertension
- Fever / chilling
- Hematuria / microhematuria
- Hepatic / liver neoplasm / tumor / carcinoma / cancer
- Lung / bronchopulmonary neoplasm / tumor / carcinoma / cancer
- Lymphadenopathy / polyadenopathies
- Weight loss / loss of appetite / break in weight curve / general health alteration


Familial pancreatic carcinoma

(no data available)