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5 OMIM references -
4 associated genes
11 signs/symptoms
COMMON GENES: 1
PROTEIN INTERACTIONS: 2
11 OMIM references -
12 associated genes
No signs/symptoms info
Nephroblastoma
Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis

DIS3L2 ACTN4
H19 ADCK4
POU6F2 ARHGAP24
WT1 CD2AP
INF2
MYO1E
NPHS1
NPHS2
PLCE1
PTPRO
TRPC6
WT1


COMMON
GENES
WT1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
H19
H19
(0.72)
(0.63)
TRPC6
CD2AP



Citations in the biomedical literature:


Nephroblastoma
DIS3L2 H19 POU6F2 WT1
Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis
ACTN4 ADCK4 ARHGAP24 CD2AP INF2 MYO1E
NPHS1 NPHS2 PLCE1 PTPRO TRPC6



Nephroblastoma
Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis

Synonym(s):
- Renal embryonic tumor
- Wilms tumor

Synonym(s):
- Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental glomerulosclerosis

Classification (Orphanet):
- Rare genetic disease
Classification (Orphanet):
- Rare genetic disease
- Rare renal disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Diseases of the genitourinary system -

Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: childhood
Average age of death: any age
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: -
Average age onset: -
Average age of death: -
Type of inheritance: autosomal dominant

External references:
5 OMIM references -
1 MeSH reference: D009396
External references:
11 OMIM references -
No MeSH references

Nephroblastoma

Very frequent
- Acute abdominal pain / colic
- Kidney / renal neoplasm / tumor / carcinoma / cancer
- Neoplasms / tumors

Occasional
- Aniridia / iris hypoplasia
- Chronic arterial hypertension
- Fever / chilling
- Hematuria / microhematuria
- Hepatic / liver neoplasm / tumor / carcinoma / cancer
- Lung / bronchopulmonary neoplasm / tumor / carcinoma / cancer
- Lymphadenopathy / polyadenopathies
- Weight loss / loss of appetite / break in weight curve / general health alteration


Familial idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis

(no data available)