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COMMON GENES: 2
2 OMIM references -
10 associated genes
No signs/symptoms info
Mitochondrial nonsyndromic sensorineural deafness with susceptibility to aminoglycoside exposure
Leber hereditary optic neuropathy

MT-CO1 MT-ATP6
MT-ND4 MT-CO1
MT-RNR1 MT-CO3
MT-TS1 MT-CYB
TRMU MT-ND1
MT-ND2
MT-ND4
MT-ND4L
MT-ND5
MT-ND6


COMMON
GENES
MT-CO1
MT-ND4



Citations in the biomedical literature:


Mitochondrial nonsyndromic sensorineural deafness with susceptibility to aminoglycoside exposure
MT-CO1 MT-ND4 MT-RNR1 MT-TS1 TRMU
Leber hereditary optic neuropathy
MT-ATP6 MT-CO3 MT-CYB MT-ND1 MT-ND2
MT-ND4L MT-ND5 MT-ND6



Mitochondrial nonsyndromic sensorineural deafness with susceptibility to aminoglycoside exposure
Leber hereditary optic neuropathy

Synonym(s):
- Mitochondrial isolated neurosensory deafness with susceptibility to aminoglycoside exposure
- Mitochondrial isolated neurosensory hearing loss with susceptibility to aminoglycoside exposure
- Mitochondrial isolated sensorineural deafness with susceptibility to aminoglycoside exposure
- Mitochondrial isolated sensorineural hearing loss with susceptibility to aminoglycoside exposure
- Mitochondrial nonsyndromic neurosensory deafness with susceptibility to aminoglycoside exposure
- Mitochondrial nonsyndromic neurosensory hearing loss with susceptibility to aminoglycoside exposure
- Mitochondrial nonsyndromic sensorineural hearing loss with susceptibility to aminoglycoside exposure

Synonym(s):
- LHON
- Leber optic atrophy

Classification (Orphanet):
- Inborn errors of metabolism
- Rare genetic disease
- Rare otorhinolaryngologic disease
Classification (Orphanet):
- Inborn errors of metabolism
- Rare cardiac disease
- Rare eye disease
- Rare genetic disease

Classification (ICD10):
(no data available)
Classification (ICD10):
- Diseases of the eye and adnexa -

Epidemiological data:
Class of prevalence: unknown
Average age onset: variable
Average age of death: -
Type of inheritance: mitochondrial inheritance
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adolescence / young
Average age of death: normal
Type of inheritance: mitochondrial inheritance

External references:
1 OMIM reference -
No MeSH references
External references:
2 OMIM references -
No MeSH references

No signs/symptoms info available.