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1 OMIM reference -
14 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 2
8 OMIM references -
9 associated genes
No signs/symptoms info
Microform holoprosencephaly
Familial thoracic aortic aneurysm and aortic dissection

CDON ACTA2
DISP1 FBN1
DLL1 MYH11
FGF8 MYLK
FOXH1 PRKG1
GAS1 SMAD3
GLI2 TGFB2
NODAL TGFBR1
PTCH1 TGFBR2
SHH
SIX3
TDGF1
TGIF1
ZIC2


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
FOXH1
TGIF1
(0.9)
(0.84)
SMAD3
SMAD3



Citations in the biomedical literature:


Microform holoprosencephaly
CDON DISP1 DLL1 FGF8 FOXH1 GAS1
GLI2 NODAL PTCH1 SHH SIX3 TDGF1
TGIF1 ZIC2
Familial thoracic aortic aneurysm and aortic dissection
ACTA2 FBN1 MYH11 MYLK PRKG1 SMAD3
TGFB2 TGFBR1 TGFBR2



Microform holoprosencephaly
Familial thoracic aortic aneurysm and aortic dissection

Synonym(s):
- Microform HPE

Synonym(s):
- Familial TAAD

Classification (Orphanet):
(no data available)
Classification (Orphanet):
- Rare circulatory system disease
- Rare genetic disease
- Rare surgical thoracic disease
- Rare systemic or rheumatologic disease

Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -
Classification (ICD10):
- Diseases of the circulatory system -

Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: neonatal/infancy
Average age of death: adult
Type of inheritance: multigenic/multifactorial
Epidemiological data:
Class of prevalence: -
Average age onset: -
Average age of death: -
Type of inheritance: autosomal dominant

External references:
1 OMIM reference -
No MeSH references
External references:
8 OMIM references -
No MeSH references

No signs/symptoms info available.