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1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 1
2 associated genes
19 signs/symptoms
Machado-Joseph disease type 3
Desmoplastic small round cell tumor

ATXN3 EWSR1
WT1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
ATXN3
(0.63)
EWSR1



Citations in the biomedical literature:


Machado-Joseph disease type 3
ATXN3
Desmoplastic small round cell tumor
EWSR1 WT1



Machado-Joseph disease type 3
Desmoplastic small round cell tumor

Synonym(s):
- SCA3, Machado type

Synonym(s):
- DSRCT

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare abdominal surgical disease
- Rare oncologic disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: unknown
Average age onset: adolescence / young
Average age of death: -
Type of inheritance: sporadic

External references:
No OMIM references
No MeSH references
External references:
No OMIM references
1 MeSH reference: D058405

Desmoplastic small round cell tumor

Very frequent
- Acute abdominal pain / colic
- Digestive neoplasm / tumor / carcinoma / cancer
- Lymphadenopathy / polyadenopathies
- Peritoneal diseases
- Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma

Frequent
- Hepatomegaly / liver enlargement (excluding storage disease)
- Intestinal obstruction / ileus
- Mediastinal / hilar adenopathies
- Nausea / vomiting / regurgitation / merycism / hyperemesis
- Weight loss / loss of appetite / break in weight curve / general health alteration

Occasional
- Anaemia
- Ascitis
- Central nervous system / peripheral nerves neoplasm / tumor / carcinoma / cancer
- Lung / bronchopulmonary neoplasm / tumor / carcinoma / cancer
- Nose / nasal sinus neoplasm / tumor / carcinoma / cancer
- Ovary / Fallopian tube neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma)
- Pancreatic / pancreas neoplasm / tumor / carcinoma / cancer
- Testis anomalies
- Wasted (excluding lipodystrophy) / poorly muscled build / cachexy


Machado-Joseph disease type 3

(no data available)