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6 OMIM references -
9 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
16 OMIM references -
4 associated genes
No signs/symptoms info
Isolated CoQ-cytochrome C reductase deficiency
Early-onset autosomal dominant Alzheimer disease

BCS1L APP
CYC1 PSEN1
LYRM7 PSEN2
MT-CYB SORL1
TTC19
UQCC2
UQCRB
UQCRC2
UQCRQ


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
LYRM7
(0.56)
APP



Citations in the biomedical literature:


Isolated CoQ-cytochrome C reductase deficiency
BCS1L CYC1 LYRM7 MT-CYB TTC19 UQCC2
UQCRB UQCRC2 UQCRQ
Early-onset autosomal dominant Alzheimer disease
APP PSEN1 PSEN2 SORL1



Isolated CoQ-cytochrome C reductase deficiency
Early-onset autosomal dominant Alzheimer disease

Synonym(s):
- Isolated coenzyme Q-cytochrome C reductase deficiency
- Isolated mitochondrial respiratory chain complex III deficiency
- Isolated ubiquinone-cytochrome C reductase deficiency

Synonym(s):
- EOFAD
- Early-onset familial autosomal dominant Alzheimer disease
- Familial Alzheimer disease

Classification (Orphanet):
- Inborn errors of metabolism
- Rare genetic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Diseases of the nervous system -

Epidemiological data:
Class of prevalence: -
Average age onset: -
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: adult
Type of inheritance: autosomal dominant

External references:
6 OMIM references -
No MeSH references
External references:
16 OMIM references -
No MeSH references

No signs/symptoms info available.