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2 OMIM references -
2 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 3
4 associated genes
16 signs/symptoms
Hypohidrotic ectodermal dysplasia with immunodeficiency
MALT lymphoma

IKBKG BIRC3
NFKBIA FOXP1
IGH
MALT1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
IKBKG
IKBKG
NFKBIA
(0.86)
(0.84)
(0.63)
MALT1
BIRC3
MALT1



Citations in the biomedical literature:


Hypohidrotic ectodermal dysplasia with immunodeficiency
IKBKG NFKBIA
MALT lymphoma
BIRC3 FOXP1 IGH MALT1



Hypohidrotic ectodermal dysplasia with immunodeficiency
MALT lymphoma

Synonym(s):
- Anhidrotic ectodermal dysplasia with immunodeficiency
- EDA-ID
- HED-ID

Synonym(s):
- Extranodal marginal zone B-cell lymphoma
- MALToma
- Mucosa-associated lymphatic tissue lymphoma
- Mucosa-associated lymphoid tissue lymphoma

Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare genetic disease
- Rare immune disease
- Rare skin disease
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: unknown
Average age onset: neonatal/infancy
Average age of death: child / adolescent
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: normal
Type of inheritance: multigenic/multifactorial

External references:
2 OMIM references -
No MeSH references
External references:
No OMIM references
No MeSH references

MALT lymphoma

Very frequent
- Asthenia / fatigue / weakness
- Epigastralgia / heartburn / gastric / duodenal ulcer / gastritis
- Fever / chilling
- Hematologic / blood / lymphatic cancer
- Hyperhidrosis / increased sweating
- Lung / pulmonary infiltrates
- Nausea / vomiting / regurgitation / merycism / hyperemesis
- Weight loss / loss of appetite / break in weight curve / general health alteration

Frequent
- Constipation

Occasional
- Acute abdominal pain / colic
- Chronic uveitis / blepharitis / episcleritis / scleritis / conjonctivitis / keratitis
- Defect / anomaly of lacrimal system
- Lymphadenopathy / polyadenopathies
- Mediastinal / hilar adenopathies
- Repeat respiratory infections
- Thyroid anomalies


Hypohidrotic ectodermal dysplasia with immunodeficiency

(no data available)