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1 OMIM reference -
1 associated gene
8 signs/symptoms
PROTEIN INTERACTIONS: 1
1 OMIM reference -
1 associated gene
No signs/symptoms info
Huntington disease
Syndromic multisystem autoimmune disease due to Itch deficiency

HTT ITCH


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
HTT
(0.65)
ITCH



Citations in the biomedical literature:


Huntington disease
HTT
Syndromic multisystem autoimmune disease due to Itch deficiency
ITCH



Huntington disease
Syndromic multisystem autoimmune disease due to Itch deficiency

Synonym(s):
- Huntington chorea

Synonym(s):
(no synonyms)

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare gastroenterologic disease
- Rare genetic disease
- Rare immune disease
- Rare neurologic disease
- Rare respiratory disease
- Rare systemic or rheumatologic disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
(no data available)

Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: variable
Average age of death: any age
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: autosomal recessive

External references:
1 OMIM reference -
1 MeSH reference: D006816
External references:
1 OMIM reference -
No MeSH references

Huntington disease

Frequent
- Abnormal cry / voice / phonation disorder / nasal speech
- Autosomal dominant inheritance
- Cortical atrophy without hydrocephaly / cerebral hemiatrophy / subcortical atrophy
- EEG anomalies
- Hypertonia / spasticity / rigidity / stiffness
- Movement disorder
- Psychic / behavioural troubles
- Psychic / psychomotor regression / dementia / intellectual decline



Syndromic multisystem autoimmune disease due to Itch deficiency

(no data available)