Cytoscape Web
Click node...


3 OMIM references -
4 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 1
16 OMIM references -
4 associated genes
No signs/symptoms info
Homozygous familial hypercholesterolemia
Early-onset autosomal dominant Alzheimer disease

APOB APP
LDLR PSEN1
LDLRAP1 PSEN2
PCSK9 SORL1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
LDLRAP1
(0.67)
APP



Citations in the biomedical literature:


Homozygous familial hypercholesterolemia
APOB LDLR LDLRAP1 PCSK9
Early-onset autosomal dominant Alzheimer disease
APP PSEN1 PSEN2 SORL1



Homozygous familial hypercholesterolemia
Early-onset autosomal dominant Alzheimer disease

Synonym(s):
- HoFH

Synonym(s):
- EOFAD
- Early-onset familial autosomal dominant Alzheimer disease
- Familial Alzheimer disease

Classification (Orphanet):
- Inborn errors of metabolism
- Rare endocrine disease
- Rare genetic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -
Classification (ICD10):
- Diseases of the nervous system -

Epidemiological data:
Class of prevalence: -
Average age onset: -
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: adult
Type of inheritance: autosomal dominant

External references:
3 OMIM references -
No MeSH references
External references:
16 OMIM references -
No MeSH references

No signs/symptoms info available.