Cytoscape Web
Click node...


1 OMIM reference -
1 associated gene
9 signs/symptoms
COMMON GENES: 1
PROTEIN INTERACTIONS: 1
1 OMIM reference -
2 associated genes
No signs/symptoms info
Hereditary sensory and autonomic neuropathy type 4
Hereditary sensory and autonomic neuropathy type 5

NTRK1 NGF
NTRK1


COMMON
GENES
NTRK1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
NTRK1
(0.9)
NGF



Citations in the biomedical literature:


Hereditary sensory and autonomic neuropathy type 4
NTRK1
Hereditary sensory and autonomic neuropathy type 5
NGF



Hereditary sensory and autonomic neuropathy type 4
Hereditary sensory and autonomic neuropathy type 5

Synonym(s):
- HSAN4
- Insensitivity to pain - anhidrosis
- NHSA4

Synonym(s):
- Congenital insensitivity to pain and thermal analgesia
- HSAN5
- NHSA5

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
- Diseases of the nervous system -

Epidemiological data:
Class of prevalence: unknown
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: autosomal recessive

External references:
1 OMIM reference -
No MeSH references
External references:
1 OMIM reference -
1 MeSH reference: D000699

Hereditary sensory and autonomic neuropathy type 4

Very frequent
- Autosomal recessive inheritance
- Chronic skin infection / ulcerations / ulcers / cancrum
- Insensitivity to pain
- Intellectual deficit / mental / psychomotor retardation / learning disability
- Osteosclerosis / osteopetrosis / bone condensation
- Psychic / behavioural troubles

Occasional
- Dental staining anomaly / spotted teeth / erythrodontia
- Thick skin / pachydermia / orange skin
- Tight skin / lack of elasticity


Hereditary sensory and autonomic neuropathy type 5

(no data available)