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COMMON GENES: 4
PROTEIN INTERACTIONS: 2
5 OMIM references -
5 associated genes
6 signs/symptoms
Hereditary persistence of fetal hemoglobin - sickle cell disease
Hereditary persistence of fetal hemoglobin - beta-thalassemia

HBB BCL11A
HBG1 HBB
HBG2 HBG1
KLF1 HBG2
KLF1


COMMON
GENES
HBB
HBG1
HBG2
KLF1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
HBB
HBG1
(0.52)
(0.49)
HBG2
HBG2



Citations in the biomedical literature:


Hereditary persistence of fetal hemoglobin - sickle cell disease
HBB HBG1 HBG2 KLF1
Hereditary persistence of fetal hemoglobin - beta-thalassemia
BCL11A



Hereditary persistence of fetal hemoglobin - sickle cell disease
Hereditary persistence of fetal hemoglobin - beta-thalassemia

Synonym(s):
- HPFH - sickle cell disease

Synonym(s):
- HPFH - beta-thalassemia

Classification (Orphanet):
- Rare genetic disease
- Rare hematologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare hematologic disease

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

Epidemiological data:
Class of prevalence: unknown
Average age onset: variable
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: unknown
Average age onset: childhood
Average age of death: no data available
Type of inheritance: autosomal dominant

External references:
No OMIM references
No MeSH references
External references:
5 OMIM references -
No MeSH references

Hereditary persistence of fetal hemoglobin - beta-thalassemia

Very frequent
- Anaemia
- Hemoglobinosis / hemoglobinopathy
- Pallor
- Splenomegaly

Frequent
- Anomalies of bones / skeletal anomalies
- Hepatomegaly / liver enlargement (excluding storage disease)



Hereditary persistence of fetal hemoglobin - sickle cell disease

(no data available)