Cytoscape Web
Click node...


1 OMIM reference -
1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 1
1 OMIM reference -
1 associated gene
5 signs/symptoms
Hereditary cerebral hemorrhage with amyloidosis, Flemish type
Lissencephaly type 1 due to doublecortin gene mutation

APP DCX


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
APP
(0.56)
DCX



Citations in the biomedical literature:


Hereditary cerebral hemorrhage with amyloidosis, Flemish type
APP
Lissencephaly type 1 due to doublecortin gene mutation
DCX



Hereditary cerebral hemorrhage with amyloidosis, Flemish type
Lissencephaly type 1 due to doublecortin gene mutation

Synonym(s):
- HCHWA, Flemish type

Synonym(s):
- X-linked lissencephaly type 1

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
- Rare systemic or rheumatologic disease
Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
(no data available)
Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -

Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: unknown
Average age onset: neonatal/infancy
Average age of death: no data available
Type of inheritance: x-linked recessive

External references:
1 OMIM reference -
No MeSH references
External references:
1 OMIM reference -
No MeSH references

Lissencephaly type 1 due to doublecortin gene mutation

Very frequent
- Intellectual deficit / mental / psychomotor retardation / learning disability
- Seizures / epilepsy / absences / spasms / status epilepticus

Frequent
- Failure to thrive / difficulties for feeding in infancy / growth delay
- Hypertonia / spasticity / rigidity / stiffness
- Hypotonia



Hereditary cerebral hemorrhage with amyloidosis, Flemish type

(no data available)