Cytoscape Web
Click node...


1 OMIM reference -
1 associated gene
3 signs/symptoms
PROTEIN INTERACTIONS: 4
32 OMIM references -
28 associated genes
2 signs/symptoms
Hereditary cerebral hemorrhage with amyloidosis, Arctic type
Primary ciliary dyskinesia

APP ARMC4
C21ORF59
CCDC103
CCDC114
CCDC39
CCDC40
CCDC65
DNAAF1
DNAAF2
DNAAF3
DNAH11
DNAH5
DNAI1
DNAI2
DNAL1
DRC1
DYX1C1
HEATR2
HYDIN
LRRC6
NME8
OFD1
RPGR
RSPH1
RSPH4A
RSPH9
SPAG1
ZMYND10


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
APP
APP
APP
APP
(0.56)
(0.56)
(0.56)
(0.56)
C21ORF59
CCDC40
DNAAF2
NME8



Citations in the biomedical literature:


Hereditary cerebral hemorrhage with amyloidosis, Arctic type
APP
Primary ciliary dyskinesia
ARMC4 C21ORF59 CCDC103 CCDC114 CCDC39 CCDC40
CCDC65 DNAAF1 DNAAF2 DNAAF3 DNAH11 DNAH5
DNAI1 DNAI2 DNAL1 DRC1 DYX1C1 HEATR2
HYDIN LRRC6 NME8 OFD1 RPGR RSPH1
RSPH4A RSPH9 SPAG1 ZMYND10



Hereditary cerebral hemorrhage with amyloidosis, Arctic type
Primary ciliary dyskinesia

Synonym(s):
- HCHWA, Arctic type

Synonym(s):
- Immotile cilia syndrome

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
- Rare systemic or rheumatologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare infertility
- Rare respiratory disease

Classification (ICD10):
(no data available)
Classification (ICD10):
- Diseases of the respiratory system -

Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: neonatal/infancy
Average age of death: normal
Type of inheritance: autosomal dominant

External references:
1 OMIM reference -
No MeSH references
External references:
32 OMIM references -
No MeSH references

Hereditary cerebral hemorrhage with amyloidosis, Arctic type
Primary ciliary dyskinesia

Very frequent
- Autosomal dominant inheritance
- Psychic / behavioural troubles
- Psychic / psychomotor regression / dementia / intellectual decline



Very frequent
- Autosomal recessive inheritance
- Repeat respiratory infections