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1 OMIM reference -
1 associated gene
3 signs/symptoms
PROTEIN INTERACTIONS: 5
2 OMIM references -
14 associated genes
No signs/symptoms info
Hereditary cerebral hemorrhage with amyloidosis, Arctic type
Maternally-inherited Leigh syndrome

APP MT-ATP6
MT-CO1
MT-CO2
MT-CO3
MT-ND1
MT-ND2
MT-ND3
MT-ND4
MT-ND5
MT-ND6
MT-TK
MT-TL1
MT-TV
MT-TW


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
APP
APP
APP
APP
APP
(0.73)
(0.56)
(0.56)
(0.56)
(0.56)
MT-ND3
MT-TK
MT-TL1
MT-TV
MT-TW



Citations in the biomedical literature:


Hereditary cerebral hemorrhage with amyloidosis, Arctic type
APP
Maternally-inherited Leigh syndrome
MT-ATP6 MT-CO1 MT-CO2 MT-CO3 MT-ND1 MT-ND2
MT-ND3 MT-ND4 MT-ND5 MT-ND6 MT-TK MT-TL1
MT-TV MT-TW



Hereditary cerebral hemorrhage with amyloidosis, Arctic type
Maternally-inherited Leigh syndrome

Synonym(s):
- HCHWA, Arctic type

Synonym(s):
- MILS
- Maternally-inherited Leigh disease
- Maternally-inherited infantile subacute necrotizing encephalopathy

Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
- Rare systemic or rheumatologic disease
Classification (Orphanet):
- Inborn errors of metabolism
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
(no data available)
Classification (ICD10):
- Diseases of the nervous system -

Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: -
Average age onset: neonatal/infancy
Average age of death: -
Type of inheritance: mitochondrial inheritance

External references:
1 OMIM reference -
No MeSH references
External references:
2 OMIM references -
No MeSH references

Hereditary cerebral hemorrhage with amyloidosis, Arctic type

Very frequent
- Autosomal dominant inheritance
- Psychic / behavioural troubles
- Psychic / psychomotor regression / dementia / intellectual decline



Maternally-inherited Leigh syndrome

(no data available)