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2 OMIM references -
2 associated genes
10 signs/symptoms
PROTEIN INTERACTIONS: 1
3 OMIM references -
16 associated genes
No signs/symptoms info
Gray platelet syndrome
Papillary or follicular thyroid carcinoma

GFI1B CCDC6
NBEAL2 DIRC3
ERC1
FOXE1
GOLGA5
NCOA4
NDUFA13
NKX2-1
NTRK1
PCM1
RET
TFG
TPR
TRIM24
TRIM27
TRIM33


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
GFI1B
(0.63)
TRIM27



Citations in the biomedical literature:


Gray platelet syndrome
GFI1B NBEAL2
Papillary or follicular thyroid carcinoma
CCDC6 DIRC3 ERC1 FOXE1 GOLGA5 NCOA4
NDUFA13 NKX2-1 NTRK1 PCM1 RET TFG
TPR TRIM24 TRIM27 TRIM33



Gray platelet syndrome
Papillary or follicular thyroid carcinoma

Synonym(s):
- Alpha storage pool deficiency
- GPS
- Platelet alpha-granule deficiency

Synonym(s):
- Well-differentiated thyroid carcinoma

Classification (Orphanet):
- Rare genetic disease
- Rare hematologic disease
Classification (Orphanet):
- Rare endocrine disease
- Rare oncologic disease

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: childhood
Average age of death: no data available
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: -
Type of inheritance: sporadic

External references:
2 OMIM references -
1 MeSH reference: D055652
External references:
3 OMIM references -
No MeSH references

Gray platelet syndrome

Very frequent
- Bruisability
- Hemorrhage / hemorrhagic syndrome / excessive / long-lasting bleeding
- Platelet disorders / thrombopathies
- Thrombocytopenia / thrombopenia

Frequent
- Bladder / vesical lesions / glomerulations / petechiae
- Epistaxis / nose bleeding
- Metrorrhagia / menorrhagia / hemorrhagic cycles / hyper / poly / spanio / dysmenorrhea
- Myelodysplastic syndrome
- Splenomegaly

Occasional
- Early death in adulthood


Papillary or follicular thyroid carcinoma

(no data available)