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1 OMIM reference -
3 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 7
8 OMIM references -
9 associated genes
No signs/symptoms info
Generalized juvenile polyposis/juvenile polyposis coli
Familial thoracic aortic aneurysm and aortic dissection

BMPR1A ACTA2
ENG FBN1
SMAD4 MYH11
MYLK
PRKG1
SMAD3
TGFB2
TGFBR1
TGFBR2


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
ENG
ENG
SMAD4
SMAD4
SMAD4
ENG
SMAD4
(0.95)
(0.95)
(0.9)
(0.78)
(0.63)
(0.55)
(0.52)
TGFBR1
TGFBR2
SMAD3
TGFBR1
PRKG1
TGFB2
TGFBR2



Citations in the biomedical literature:


Generalized juvenile polyposis/juvenile polyposis coli
BMPR1A ENG SMAD4
Familial thoracic aortic aneurysm and aortic dissection
ACTA2 FBN1 MYH11 MYLK PRKG1 SMAD3
TGFB2 TGFBR1 TGFBR2



Generalized juvenile polyposis/juvenile polyposis coli
Familial thoracic aortic aneurysm and aortic dissection

Synonym(s):
(no synonyms)

Synonym(s):
- Familial TAAD

Classification (Orphanet):
- Rare gastroenterologic disease
- Rare genetic disease
- Rare oncologic disease
Classification (Orphanet):
- Rare circulatory system disease
- Rare genetic disease
- Rare surgical thoracic disease
- Rare systemic or rheumatologic disease

Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Diseases of the circulatory system -

Epidemiological data:
Class of prevalence: unknown
Average age onset: variable
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: -
Average age onset: -
Average age of death: -
Type of inheritance: autosomal dominant

External references:
1 OMIM reference -
No MeSH references
External references:
8 OMIM references -
No MeSH references

No signs/symptoms info available.