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1 associated gene
12 signs/symptoms
PROTEIN INTERACTIONS: 1
1 associated gene
No signs/symptoms info
Familial partial lipodystrophy due to AKT2 mutations
Familial renal amyloidosis due to Apolipoprotein AI variant

AKT2 APOA1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
AKT2
(0.63)
APOA1



Citations in the biomedical literature:


Familial partial lipodystrophy due to AKT2 mutations
AKT2
Familial renal amyloidosis due to Apolipoprotein AI variant
APOA1



Familial partial lipodystrophy due to AKT2 mutations
Familial renal amyloidosis due to Apolipoprotein AI variant

Synonym(s):
(no synonyms)

Synonym(s):
- Apolipoprotein AI amyloidosis
- Familial amyloid nephropathy due to apolipoprotein AI variant
- Hereditary amyloid nephropathy due to apolipoprotein AI variant
- Hereditary renal amyloidosis due to apolipoprotein AI variant

Classification (Orphanet):
- Rare endocrine disease
- Rare genetic disease
- Rare skin disease
Classification (Orphanet):
- Rare genetic disease
- Rare renal disease

Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -
Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: unknown
Epidemiological data:
(no data available)

External references:
No OMIM references
No MeSH references
External references:
No OMIM references
No MeSH references

Familial partial lipodystrophy due to AKT2 mutations

Very frequent
- Abnormal fat distribution / lipodystrophy
- Autosomal dominant inheritance
- Chronic arterial hypertension
- Hyperlipidemia / hypercholesterolemia / hypertriglyceridemia
- Insulin resistance
- Insulin-dependent / type 1 diabetes

Frequent
- Abnormal / polycystic ovaries
- Acanthosis nigricans
- Liver / hepatic steatosis

Occasional
- Angor pectoris / myocardial infarction
- Arterial atheroma / precocious atherosclerosis / arteriosclerosis
- Heart / cardiac failure


Familial renal amyloidosis due to Apolipoprotein AI variant

(no data available)