Cytoscape Web
Click node...


1 OMIM reference -
1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 1
2 OMIM references -
4 associated genes
No signs/symptoms info
Autoimmune lymphoproliferative syndrome with recurrent infections
Intrahepatic cholestasis of pregnancy

CASP8 ABCB11
ABCB4
ATP8B1
NR1H4


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
CASP8
(0.75)
NR1H4



Citations in the biomedical literature:


Autoimmune lymphoproliferative syndrome with recurrent infections
CASP8
Intrahepatic cholestasis of pregnancy
ABCB11 ABCB4 ATP8B1 NR1H4



Autoimmune lymphoproliferative syndrome with recurrent infections
Intrahepatic cholestasis of pregnancy

Synonym(s):
- ALPS with recurrent infections

Synonym(s):
- Gravidic intrahepatic cholestasis
- Pregnancy-related cholestasis
- Recurrent intrahepatic cholestasis of pregnancy

Classification (Orphanet):
- Rare genetic disease
- Rare immune disease
- Rare oncologic disease
Classification (Orphanet):
- Rare gynecologic or obstetric disease
- Rare hepatic disease

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Pregnancy, childbirth and the puerperium -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: childhood
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: unknown
Average age onset: adulthood
Average age of death: -
Type of inheritance: multigenic/multifactorial

External references:
1 OMIM reference -
No MeSH references
External references:
2 OMIM references -
1 MeSH reference: C535932

No signs/symptoms info available.