Cytoscape Web
Click node...


1 OMIM reference -
1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 3
16 OMIM references -
4 associated genes
No signs/symptoms info
Autoimmune lymphoproliferative syndrome with recurrent infections
Early-onset autosomal dominant Alzheimer disease

CASP8 APP
PSEN1
PSEN2
SORL1


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
CASP8
CASP8
CASP8
(0.63)
(0.55)
(0.52)
PSEN2
PSEN1
APP



Citations in the biomedical literature:


Autoimmune lymphoproliferative syndrome with recurrent infections
CASP8
Early-onset autosomal dominant Alzheimer disease
APP PSEN1 PSEN2 SORL1



Autoimmune lymphoproliferative syndrome with recurrent infections
Early-onset autosomal dominant Alzheimer disease

Synonym(s):
- ALPS with recurrent infections

Synonym(s):
- EOFAD
- Early-onset familial autosomal dominant Alzheimer disease
- Familial Alzheimer disease

Classification (Orphanet):
- Rare genetic disease
- Rare immune disease
- Rare oncologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Diseases of the nervous system -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: childhood
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: adult
Type of inheritance: autosomal dominant

External references:
1 OMIM reference -
No MeSH references
External references:
16 OMIM references -
No MeSH references

No signs/symptoms info available.