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1 OMIM reference -
1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 2
6 OMIM references -
7 associated genes
No signs/symptoms info
Autoimmune lymphoproliferative syndrome with recurrent infections
B-cell chronic lymphocytic leukemia

CASP8 ARL11
ATM
CCND1
IGHG1
IGHV3-21
()
POT1
TP53


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
CASP8
CASP8
(0.63)
(0.52)
TP53
IGHV3-21



Citations in the biomedical literature:


Autoimmune lymphoproliferative syndrome with recurrent infections
CASP8
B-cell chronic lymphocytic leukemia
ARL11 ATM CCND1 IGHG1 IGHV3-21 POT1
TP53



Autoimmune lymphoproliferative syndrome with recurrent infections
B-cell chronic lymphocytic leukemia

Synonym(s):
- ALPS with recurrent infections

Synonym(s):
- B-CLL
- B-cell chronic lymphoid leukemia
- Lymphoplasmacytic leukemia
- Lymphoplasmacytoid immunocytoma
- Small lymphocytic lymphoma

Classification (Orphanet):
- Rare genetic disease
- Rare immune disease
- Rare oncologic disease
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease

Classification (ICD10):
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -
Classification (ICD10):
- Neoplasms -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: childhood
Average age of death: -
Type of inheritance: autosomal recessive
Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adulthood
Average age of death: -
Type of inheritance: sporadic

External references:
1 OMIM reference -
No MeSH references
External references:
6 OMIM references -
1 MeSH reference: D015451

No signs/symptoms info available.